P32905

PR
Gene name
RPS0A
Protein name
40S ribosomal protein S0-A
Names
Nucleic acid-binding protein NAB1A, Small ribosomal subunit protein uS2-A
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YGR214W
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

176-252 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

122 structures for P32905

Entry ID Method Resolution Chain Position Source
3J6X EM 610 A S0 1-252 PDB
3J6Y EM 610 A S0 1-252 PDB
3J77 EM 620 A S0 1-252 PDB
3J78 EM 630 A S0 1-252 PDB
4U3M X-ray 300 A S0/s0 2-252 PDB
4U3N X-ray 320 A S0/s0 2-252 PDB
4U3U X-ray 290 A S0/s0 2-252 PDB
4U4N X-ray 310 A S0/s0 2-252 PDB
4U4O X-ray 360 A S0/s0 2-252 PDB
4U4Q X-ray 300 A S0/s0 2-252 PDB
4U4R X-ray 280 A S0/s0 2-252 PDB
4U4U X-ray 300 A S0/s0 2-252 PDB
4U4Y X-ray 320 A S0/s0 2-252 PDB
4U4Z X-ray 310 A S0/s0 2-252 PDB
4U50 X-ray 320 A S0/s0 2-252 PDB
4U51 X-ray 320 A S0/s0 2-252 PDB
4U52 X-ray 300 A S0/s0 2-252 PDB
4U53 X-ray 330 A S0/s0 2-252 PDB
4U55 X-ray 320 A S0/s0 2-252 PDB
4U56 X-ray 345 A S0/s0 2-252 PDB
4U6F X-ray 310 A S0/s0 2-252 PDB
4V4B EM 1170 A AB 14-198 PDB
4V6I EM 880 A AA 1-252 PDB
4V7R X-ray 400 A AA/CA 1-252 PDB
4V88 X-ray 300 A AA/CA 1-252 PDB
4V8Y EM 430 A AA 1-252 PDB
4V8Z EM 660 A AA 1-252 PDB
4V92 EM 370 A A 2-207 PDB
5DAT X-ray 315 A S0/s0 2-252 PDB
5DC3 X-ray 325 A S0/s0 2-252 PDB
5DGE X-ray 345 A S0/s0 2-252 PDB
5DGF X-ray 330 A S0/s0 2-252 PDB
5DGV X-ray 310 A S0/s0 2-252 PDB
5FCI X-ray 340 A S0/s0 2-252 PDB
5FCJ X-ray 310 A S0/s0 2-252 PDB
5I4L X-ray 310 A S0/s0 2-207 PDB
5JUO EM 400 A XA 1-252 PDB
5JUP EM 350 A XA 1-252 PDB
5JUS EM 420 A XA 1-252 PDB
5JUT EM 400 A XA 1-252 PDB
5JUU EM 400 A XA 1-252 PDB
5LL6 EM 390 A P 1-252 PDB
5LYB X-ray 325 A S0/s0 2-207 PDB
5M1J EM 330 A A2 2-208 PDB
5MC6 EM 380 A P 1-252 PDB
5MEI X-ray 350 A B/s0 2-207 PDB
5NDG X-ray 370 A S0/s0 2-207 PDB
5NDV X-ray 330 A S0/s0 2-207 PDB
5NDW X-ray 370 A S0/s0 2-207 PDB
5OBM X-ray 340 A S0/s0 2-207 PDB
5ON6 X-ray 310 A B/s0 2-207 PDB
5TBW X-ray 300 A B/s0 2-207 PDB
5TGA X-ray 330 A S0/s0 2-207 PDB
5TGM X-ray 350 A S0/s0 2-207 PDB
6EML EM 360 A P 1-252 PDB
6FAI EM 340 A A 1-252 PDB
6GQ1 EM 440 A q 2-207 PDB
6GQB EM 390 A q 2-207 PDB
6GQV EM 400 A q 2-207 PDB
6HHQ X-ray 310 A B/s0 1-252 PDB
6I7O EM 530 A P/Pb 2-207 PDB
6Q8Y EM 310 A P 2-220 PDB
6RBD EM 347 A A 1-252 PDB
6RBE EM 380 A A 1-252 PDB
6S47 EM 328 A BB 2-252 PDB
6SNT EM 280 A A 1-252 PDB
6SV4 EM 330 A P/Pb/Pc 1-252 PDB
6T4Q EM 260 A SA 2-207 PDB
6T7I EM 320 A SA 1-252 PDB
6T7T EM 310 A SA 2-207 PDB
6T83 EM 400 A Ab/b 1-252 PDB
6TB3 EM 280 A P 2-207 PDB
6TNU EM 310 A P 2-207 PDB
6WDR EM 370 A A 2-207 PDB
6XIQ EM 420 A q 1-252 PDB
6XIR EM 320 A q 1-252 PDB
6Y7C EM 380 A A 1-252 PDB
6Z6J EM 340 A SA 1-252 PDB
6Z6K EM 340 A SA 1-252 PDB
6ZCE EM 530 A B 1-252 PDB
6ZU9 EM 620 A P 1-252 PDB
6ZVI EM 300 A i 2-207 PDB
7A1G EM 300 A P 2-207 PDB
7B7D EM 330 A P 2-207 PDB
7MPI EM 305 A BA 2-207 PDB
7MPJ EM 270 A BA 2-207 PDB
7N8B EM 305 A BA 2-207 PDB
7NRC EM 390 A SP 2-207 PDB
7NRD EM 436 A SP 2-207 PDB
7ZPQ EM 347 A AA 2-207 PDB
7ZRS EM 480 A AA 2-207 PDB
7ZUW EM 430 A AA 2-207 PDB
7ZUX EM 250 A DA 2-207 PDB
7ZW0 EM 240 A sP 1-252 PDB
8BN3 EM 240 A S0 2-252 PDB
8BQD EM 390 A P 2-207 PDB
8BQX EM 380 A P 2-207 PDB
8C01 EM 270 A P 1-252 PDB
8C83 EM 300 A P 1-252 PDB
8CAH EM 300 A P 1-252 PDB
8CAS EM 330 A P 1-252 PDB
8CBJ EM 380 A A 1-252 PDB
8CCS EM 197 A d 1-252 PDB
8CDL EM 272 A d 1-252 PDB
8CDR EM 204 A d 1-252 PDB
8CEH EM 205 A d 1-252 PDB
8CF5 EM 271 A d 1-252 PDB
8CG8 EM 257 A d 1-252 PDB
8CGN EM 228 A d 1-252 PDB
8CIV EM 247 A d 1-252 PDB
8CKU EM 311 A d 1-252 PDB
8CMJ EM 379 A d 1-252 PDB
8EUB EM 252 A BA 1-252 PDB
8EVP EM 238 A BA 1-252 PDB
8EVQ EM 272 A BA 1-252 PDB
8EVR EM 287 A BA 1-252 PDB
8EVS EM 262 A BA 1-252 PDB
8EVT EM 220 A BA 1-252 PDB
8EWB EM 287 A BA 1-252 PDB
8EWC EM 245 A BA 1-252 PDB
8Y0U EM 359 A SA 1-252 PDB
AF-P32905-F1 Predicted AlphaFoldDB

1 variants for P32905

Variant ID(s) Position Change Description Diseaes Association Provenance
s07-921396 121 V>A No SGRP

No associated diseases with P32905

2 regional properties for P32905

Type Name Position InterPro Accession
conserved_site Ribosomal protein S2, conserved site 14 - 25 IPR018130-1
conserved_site Ribosomal protein S2, conserved site 118 - 142 IPR018130-2

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
90S preribosome A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.
cytoplasmic stress granule A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
cytosolic small ribosomal subunit The small subunit of a ribosome located in the cytosol.

1 GO annotations of molecular function

Name Definition
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

6 GO annotations of biological process

Name Definition
cytoplasmic translation The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Endonucleolytic cleavage at the 3'-end of the SSU-rRNA from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA.
ribosomal small subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit.
rRNA export from nucleus The directed movement of rRNA from the nucleus to the cytoplasm; the rRNA is usually in the form of ribonucleoproteins.
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P46654 RPS0B 40S ribosomal protein S0-B Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
P38979 sta 40S ribosomal protein SA Drosophila melanogaster (Fruit fly) PR
P46769 rps-0 40S ribosomal protein SA Caenorhabditis elegans PR
10 20 30 40 50 60
MSLPATFDLT PEDAQLLLAA NTHLGARNVQ VHQEPYVFNA RPDGVHVINV GKTWEKLVLA
70 80 90 100 110 120
ARIIAAIPNP EDVVAISSRT FGQRAVLKFA AHTGATPIAG RFTPGSFTNY ITRSFKEPRL
130 140 150 160 170 180
VIVTDPRSDA QAIKEASYVN IPVIALTDLD SPSEFVDVAI PCNNRGKHSI GLIWYLLARE
190 200 210 220 230 240
VLRLRGALVD RTQPWSIMPD LYFYRDPEEV EQQVAEEATT EEAGEEEAKE EVTEEQAEAT
250
EWAEENADNV EW