P41843

PR
Gene name
T20B12.3
Protein name
Uncharacterized protein T20B12.3
Names
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_T20B12.3
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-78 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P41843

Entry ID Method Resolution Chain Position Source
AF-P41843-F1 Predicted AlphaFoldDB

No variants for P41843

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P41843

No associated diseases with P41843

1 regional properties for P41843

Type Name Position InterPro Accession
domain CCAAT-binding factor 248 - 394 IPR005612

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
Noc4p-Nop14p complex A heterodimer associated with precursors of the eukaryotic small ribosomal subunit, including the 90S preribosome; involved in small subunit biogenesis.
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
small-subunit processome A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
ribosome biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.

5 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q06512 NOC4 Nucleolar complex protein 4 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q5ZJC7 NOC4L Nucleolar complex protein 4 homolog Gallus gallus (Chicken) PR
Q9BVI4 NOC4L Nucleolar complex protein 4 homolog Homo sapiens (Human) PR
Q8BHY2 Noc4l Nucleolar complex protein 4 homolog Mus musculus (Mouse) PR
Q5I0I8 Noc4l Nucleolar complex protein 4 homolog Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MDDDLDQFFH DDAEQNADFS DDGSEDEAPD NVDVNYELER EEPKSKSVAE FTKFLQECEY
70 80 90 100 110 120
PDDIIKYFKT IKFFEKDAKT GDIVSTKSLK FTVTGFIQYL FGTKRIQRPV LRGIAKIFGR
130 140 150 160 170 180
YDIFHLISPE LVKSITHLKE TRTTAWFNLF NFLSFVPHPT DRVTKPLFRQ FCVRTPFNDK
190 200 210 220 230 240
SMKKRKLTWI STDYDNVWMA VMNGKISDKL TLKLIPYITQ NVISKLKAPF KSADFFFKMF
250 260 270 280 290 300
DKTDYHGILS LGAIFRLISE HNFEYPKFYD KVYSLTNPSL LYMSQKESIL TLLDSFLSST
310 320 330 340 350 360
HLPTYITASF LKRLSRCLLL APIDAQEPIL GLIRNLVIRH PNCSELVHRE VPQTLYDDPF
370 380 390 400 410 420
DNDETDLHKT RALESSLWEM KLLQCHWNQS VRKRAHFVDK SIQKIESYVR FRCTDELFSV
430 440 450 460 470 480
NMAKSFGGED GEAEKYRKLQ DGDEDEEGTG KPEPKKARRK GFGGKFAPKH EEKVTRAVGV
490 500
NSEAPKGILD RQVPIIDVPT LWKI