P34416

PR
Gene name
F42H10.3
Protein name
LIM and SH3 domain protein F42H10.3
Names
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_F42H10.3
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

41-295 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P34416

Entry ID Method Resolution Chain Position Source
AF-P34416-F1 Predicted AlphaFoldDB

No variants for P34416

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P34416

No associated diseases with P34416

4 regional properties for P34416

Type Name Position InterPro Accession
repeat Nebulin repeat 63 - 97 IPR000900-1
repeat Nebulin repeat 99 - 129 IPR000900-2
domain SH3 domain 266 - 327 IPR001452
domain Zinc finger, LIM-type 4 - 65 IPR001781

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cell junction A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella.
focal adhesion A cell-substrate junction that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. In insects focal adhesion has also been referred to as hemi-adherens junction (HAJ).
striated muscle dense body A vinculin-containing myofibril attachment structure of striated muscle that connects sarcomeres to the extracellular matrix. In nematode body wall muscle, the dense body performs the dual role of Z-disk and costamere.

2 GO annotations of molecular function

Name Definition
actin filament binding Binding to an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
metal ion binding Binding to a metal ion.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q3B7M5 LASP1 LIM and SH3 domain protein 1 Bos taurus (Bovine) PR
Q14847 LASP1 LIM and SH3 domain protein 1 Homo sapiens (Human) PR
Q61792 Lasp1 LIM and SH3 domain protein 1 Mus musculus (Mouse) PR
Q99MZ8 Lasp1 LIM and SH3 domain protein 1 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MSKKCAREDC GKTVYPVEEL KCLDKVWHKQ CFKCTVCGMT LNMKNYKGYD KRPYCDPHYP
70 80 90 100 110 120
KTVASVMADT PEMRRIAENT KNQSNIKYHA EYEKMKGTKI EIADDPEMER LKKNTQVQSN
130 140 150 160 170 180
VSYHGVLDQK ARQEEVRPKE EISPNPTPTP ISPMNHQSYS APTQAVAANT HLIYSTEQGG
190 200 210 220 230 240
AVSPTPQKSI GSIADYDPMN GQWGTAAAQP RNSEKLGYLK AQVDKGPARF CADFAGAPPP
250 260 270 280 290 300
SSNSISSTSP HSTLSSPQST ISPTGKAGFA VKAIYDYAAA DKDEISFLEG DIIVNCEKID
310 320 330
DGWMTGTVQR TLQWGMLPAN YVQPHKLPTG LHRLS