P34268
Gene name |
fli-1 (B0523.5) |
Protein name |
Protein flightless-1 homolog |
Names |
|
Species |
Caenorhabditis elegans |
KEGG Pathway |
cel:CELE_B0523.5 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P34268
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P34268-F1 | Predicted | AlphaFoldDB |
No variants for P34268
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P34268 | |||||
No associated diseases with P34268
1 regional properties for P34268
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Pentatricopeptide repeat | 172 - 200 | IPR002885 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| actin cytoskeleton | The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes. |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| actin filament binding | Binding to an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits. |
| phosphatidylinositol-4,5-bisphosphate binding | Binding to phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| actin filament severing | The process in which an actin filament is broken down into smaller filaments. |
| actin polymerization or depolymerization | Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament. |
| barbed-end actin filament capping | The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits. |
| myofibril assembly | Formation of myofibrils, the repeating units of striated muscle. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSTGVLQFVK | GIDFSGNDFS | GDRFPHDVEQ | MTQMTWLKLN | DSKLEQVPDE | LSRCANLEHL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QMAHNQLISV | HGELSDLPRL | RSVIVRDNNL | KTAGIPTDIF | RMKDLTIIDL | SRNQLREVPT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NLEYAKGSIV | LNLSYNNIET | IPNSVCANLI | DLLFLDLSNN | KLDMLPPQIR | RLSMLQSLKL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SNNPLNHFQL | KQLPSMTSLS | VLHMSNTNRT | LDNIPPTLDD | MHNLRDVDFS | ENNLPIVPEA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LFKLRNLRKL | NLSGNKIEKL | NMTEGEWENL | ETLNMSHNQL | TVLPDCVVKL | TRLTKLYAAN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NQLTFEGIPS | GIGKLIQLTV | LHLSYNKLEL | VPEGISRCVK | LQKLKLDHNR | LITLPEGIHL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LPDLKVLDLH | ENENLVMPPK | PNDARKKLAF | YNIDFSLEHQ | RKIAGQMTSP | SSSISSVHSG |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GARQDALARR | KEFIRRRKQQ | ADQQSADKVI | QGMSKIAGVG | AALTEKQQEE | EERQLEAKSA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VNWKKNIEKN | RRHIDYSDIF | DEDVGSDEGM | WVWEIENFYP | SIMDEAFHGQ | FYDADAYLVL |
| 550 | 560 | 570 | 580 | 590 | 600 |
| KTTREASGQL | RHAIFYWLGE | HASLDKGMCS | AVHAVGLRNH | LNATCRTQRE | EMNDETEEFL |
| 610 | 620 | 630 | 640 | 650 | 660 |
| TLFGEEIVYI | EGGRTISGFY | TTEKPAHLTR | LYRAGVNGTA | VEMEPVPLSV | ESLDPRFCFL |
| 670 | 680 | 690 | 700 | 710 | 720 |
| LDAGETIWIW | SGYKSRITVS | NKARLFAERL | NKRDRKGKSE | IETCRQARCP | PEFWQALTGN |
| 730 | 740 | 750 | 760 | 770 | 780 |
| PDKPQGAIVE | HVPEGFVAER | KKLYKVNIGM | GFLELPQVEL | PKGIAKQDML | GSKGVFVLDS |
| 790 | 800 | 810 | 820 | 830 | 840 |
| NSDIFLWIGK | KANRLLKMAG | QKLVVELHQM | IDRPDYAQVY | RETEGEESMM | FRSKFAGWDE |
| 850 | 860 | 870 | 880 | 890 | 900 |
| IVPVDYTRTS | DSVQRVPDLK | VIVKKDNMMR | ADLAALFLER | QPSMSYEESE | ELMEDCNYDL |
| 910 | 920 | 930 | 940 | 950 | 960 |
| ELMESFVLEG | KKFVKLPQKE | FGIFYTMDCY | VFLCRYAVMP | EEDEEGEDEH | DEDDKPEMDF |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| KCVVYFWQGR | DASNMGWLNF | TFQLQPNFEE | IFKDKLEVVR | MYQQQENHKF | LSHFKRKFLI |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| KRGRRGLTKN | LGGKWPELFQ | MRANGSSVCN | RTIQVDCQAN | QLCSAFCHML | RIPFKEIEED |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| GHRGVVYVWM | GKDSDPREHE | FARQVASDLV | VRDDDNDFRI | VEVQEGEENE | EFWKVLGGKK |
| 1150 | 1160 | 1170 | 1180 | 1190 | 1200 |
| KYETDSSFVK | HTRLFRCTNE | KGYFAISEKT | VDFCQDDLDD | DDIMILDNGD | AVFLWIGARS |
| 1210 | 1220 | 1230 | 1240 | 1250 | |
| SDIEAKLSYQ | AAQVYHASMR | MKANEKPRKF | MLAVRGRESC | RFRKCFHAWS | KMKEPMG |