P33438

PR
Gene name
Glt (CG9280)
Protein name
Glutactin
Names
Species
Drosophila melanogaster (Fruit fly)
KEGG Pathway
dme:Dmel_CG9280
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

567-1026 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P33438

Entry ID Method Resolution Chain Position Source
AF-P33438-F1 Predicted AlphaFoldDB

No variants for P33438

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P33438

No associated diseases with P33438

2 regional properties for P33438

Type Name Position InterPro Accession
domain Carboxylesterase, type B 59 - 570 IPR002018
conserved_site Carboxylesterase type B, conserved site 143 - 153 IPR019819

Functions

Description
EC Number
Subcellular Localization
  • Secreted, extracellular space, extracellular matrix, basement membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
basement membrane A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
vesicle lumen The volume enclosed by the membrane or protein that forms a vesicle.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

4 GO annotations of biological process

Name Definition
defense response to other organism Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism.
hemolymph coagulation Any process in which factors in the hemolymph (the invertebrate equivalent of vertebrate blood and lymph) precipitate into insoluble clots in order to prevent loss of body fluid, and at the same time prevent the movement of microbes. Hemolymph coagulation is also part of the invertebrate humoral immune response.
motor neuron axon guidance The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.
synaptic target inhibition The process in which a neuronal cell in a multicellular organism recognizes chemorepellent signals that inhibit its growth toward the source.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P08171 Est-6 Esterase-6 Drosophila melanogaster (Fruit fly) PR
Q8QZR3 Ces2a Pyrethroid hydrolase Ces2a Mus musculus (Mouse) PR
10 20 30 40 50 60
MKPLLLVLAL CGAQVHAHSV GLRPDYNDYS DEDTRRDWLP EPLKPVPWQS ETRYAQPQEA
70 80 90 100 110 120
VVQAPEVGQI LGISGHKTIA NRPVNAFLGI RYGTVGGGLA RFQAAQPIGY QGRVNATVQS
130 140 150 160 170 180
PNCAQFPELD RLRLSESRGE NVDDCLTLDI YAPEGANQLP VLVFVHGEML FDGGSEEAQP
190 200 210 220 230 240
DYVLEKDVLL VSINYRLAPF GFLSALTDEL PGNVALSDLQ LALEWLQRNV VHFGGNAGQV
250 260 270 280 290 300
TLVGQAGGAT LAHALSLSGR AGNLFQQLIL QSGTALNPYL IDNQPLDTLS TFARLARCPP
310 320 330 340 350 360
PSINPSAQGL KPLYDCLARL PTSQLVAAFE QLLLQNEHLG LTQLGGFKLV VGDPLGFLPS
370 380 390 400 410 420
HPASLATNSS LALPMIIGAT KDASAFIVSR IYDQLARLQS RNVSDYIDVV LRHTAPPSEH
430 440 450 460 470 480
RLWKQWALRE IFTPIQEQTA SLQTVAPGLL ELSNYILYRA PVINSISQSY RSVPAYLYTF
490 500 510 520 530 540
DYRGEHHRFG HLSNPLPFGV DASLSDDSVY LFPYPPEASR LNPLDRSLSR ALVTMWVNFA
550 560 570 580 590 600
TTGVPNPSSG VWPQATSEYG PFLRFTNNQQ SPLELDPHFG EGIYLPNYRV IYKPTTNFSP
610 620 630 640 650 660
PITTTTTTTT TTTTTSRPYA YNPYANWQNR PSQQHPNWHP ADPEYVRAQE ARQQEFIRER
670 680 690 700 710 720
EQRRREQQLR DQQRYPQQEP REQQDERIRQ QREQEERLRQ QREQEERLRQ QRELEERIRQ
730 740 750 760 770 780
QQEREQYERE QQEREQRERE ELERQQRERE QQQPEQQPEY NPEPVNPWGY PVQEPQPDDN
790 800 810 820 830 840
PEDGRLPYPS YEQYGPEGNE NLPETDANRN FSEEDREQQQ QEQLRREQQE QQEREYQLQL
850 860 870 880 890 900
EREQQEREQQ ERGQQEPGPE EYPSYEEYSR ALQEKNAERD RIYAEEQERE RQQQETLLQE
910 920 930 940 950 960
NQQHPEQSLP EEQPTHPNYE AYDGDRSYAE EQEREQQRRD QVEQEREEQP DEDQGEEYER
970 980 990 1000 1010 1020
SPDEEEAAEQ DVLKVEDFPS YEAYLEAATK LREEQEEQEK LEEERYRAQQ EEEDRIQAER
ERNSRN