P25360
Gene name |
PHO87 (YCR037C, YCR37C, YCR524) |
Protein name |
Inorganic phosphate transporter PHO87 |
Names |
|
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YCR037C |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P25360
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P25360-F1 | Predicted | AlphaFoldDB |
10 variants for P25360
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s03-197156 | 9 | Y>F | No | SGRP | |
| s03-197018 | 55 | P>L | No | SGRP | |
| s03-196968 | 72 | S>P | No | SGRP | |
| s03-196675 | 169 | K>N | No | SGRP | |
| s03-196676 | 169 | K>R | No | SGRP | |
| s03-196241 | 314 | S>N | No | SGRP | |
| s03-196127 | 352 | S>T | No | SGRP | |
| s03-195839 | 448 | L>W | No | SGRP | |
| s03-195102 | 694 | G>S | No | SGRP | |
| s03-194540 | 881 | K>R | No | SGRP |
No associated diseases with P25360
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cell periphery | The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| inorganic phosphate transmembrane transporter activity | Enables the transfer of a inorganic phosphate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| anion transmembrane transport | The process in which an anion is transported across a membrane. |
| phosphate ion transport | The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| plasma membrane selenite transport | The directed movement of inorganic selenite (HSeO3-1 at physiological pH) across a plasma membrane. |
| polyphosphate metabolic process | The chemical reactions and pathways involving a polyphosphate, the anion or salt of polyphosphoric acid. |
| regulation of phosphate transmembrane transport | Any process that modulates the frequency, rate or extent of phosphate transmembrane transport. |
2 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P39535 | PHO90 | Low-affinity phosphate transporter PHO90 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| P27514 | PHO91 | Low-affinity phosphate transporter PHO91 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRFSHFLKYN | AVPEWQNHYL | DYNELKNLIY | TLQTDELKQE | TPTGDLNDDA | DSQTPGPIAD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IESNIAAGEP | SSSKRRFTHK | LKRKLFGSKT | PSGSKRGDSD | EKAIDGNNIN | EETIELDELS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PQGKTTSFNK | NFIRKKFFES | RSSSVSSEGK | TLFSSYDTFV | TNLSDEKLKV | DDFYKRMEAK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FYERFDHLIN | DLEKEGIVTR | LNETFNPEIQ | ALPPLREIIS | GTSETHSSNN | PFEIHSSNID |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SELRNRFDYS | EEEMDEDDDV | DVFADTTDNT | ALLNYSQFNI | KSQKKSLLKQ | TIINLYIDLC |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QLKSFIELNR | MGFSKITKKS | DKVLHMNTRQ | ELIESEEFFK | DTYIFQHETL | SSLNSKIAQL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| IEFYAVLMGQ | PGNVDSCKQE | LKSYLHDHIV | WERSNTWKDM | LGLSSQNNDI | ITIEDEAEKL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| MQEKLQIEYF | KYPLPKPINL | KFTKIENLAV | PKLFFGKRAM | KIGFIIIVTG | VLLGVKTFND |
| 490 | 500 | 510 | 520 | 530 | 540 |
| PVEHRCMALV | ECCAFLWASE | AIPLHITGLL | VPLLTVLFRV | LKDDDGKVMG | AAAASTEILG |
| 550 | 560 | 570 | 580 | 590 | 600 |
| TMWSSTIMIL | LAGFTLGEAL | SQYNVAKVLA | SWLLALAGTK | PRNVLLMAMS | VVFFLSMWIS |
| 610 | 620 | 630 | 640 | 650 | 660 |
| NVASPVLTYS | LLTPLLDPLD | YTSPFAKALV | MGVALSADIG | GMASPISSPQ | NIISMQYLKP |
| 670 | 680 | 690 | 700 | 710 | 720 |
| YGIGWGQFFA | VALPTGILSM | LCSWALMILT | FKIGKTKLEK | FKPIRTRFTI | KQYFIIIVTI |
| 730 | 740 | 750 | 760 | 770 | 780 |
| ATILLWCVES | QIESAFGSSG | EIAVIPIVLF | FGTGLLSTKD | FNTFPWSIVV | LAMGGIALGK |
| 790 | 800 | 810 | 820 | 830 | 840 |
| AVSSSGLLVT | IARALQKKIQ | NDGVFAILCI | FGILMLVVGT | FVSHTVSAII | IIPLVQEVGD |
| 850 | 860 | 870 | 880 | 890 | 900 |
| KLSDPKAAPI | LVFGCALLAS | CGMGLASSGF | PNVTAISMTD | KKGNRWLTVG | AFISRGVPAS |
| 910 | 920 | ||||
| LLAFVCVITL | GYGISSSVLK | GST |