Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P14714

Entry ID Method Resolution Chain Position Source
AF-P14714-F1 Predicted AlphaFoldDB

102 variants for P14714

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH11978013 5 T>S No 1000Genomes
ENSVATH00675472 9 C>Y No 1000Genomes
ENSVATH00675473 27 A>T No 1000Genomes
ENSVATH11978036 44 A>T No 1000Genomes
ENSVATH00675474 46 I>V No 1000Genomes
tmp_5_14008220_C_T 58 P>S No 1000Genomes
ENSVATH07219053 61 A>V No 1000Genomes
ENSVATH07219054 77 P>T No 1000Genomes
ENSVATH00675476 82 I>V No 1000Genomes
tmp_5_14008322_A_T 92 I>F No 1000Genomes
tmp_5_14008336_A_C 96 E>D No 1000Genomes
tmp_5_14008396_A_T 116 E>D No 1000Genomes
ENSVATH11978040 119 T>S No 1000Genomes
tmp_5_14008434_T_A 129 L>Q No 1000Genomes
ENSVATH03246905 137 E>Q No 1000Genomes
tmp_5_14008460_A_G 138 K>E No 1000Genomes
tmp_5_14008499_A_G 151 I>V No 1000Genomes
tmp_5_14008535_T_A 163 Y>N No 1000Genomes
tmp_5_14008544_C_A 166 L>M No 1000Genomes
tmp_5_14008592_C_A 182 P>T No 1000Genomes
ENSVATH03246907 205 R>K No 1000Genomes
ENSVATH03246910 230 G>S No 1000Genomes
tmp_5_14008742_G_C 232 D>H No 1000Genomes
ENSVATH09506188 233 R>T No 1000Genomes
ENSVATH03246911 249 A>S No 1000Genomes
ENSVATH07219060 251 C>Y No 1000Genomes
tmp_5_14008814_A_T 256 M>L No 1000Genomes
tmp_5_14008916_G_A 290 A>T No 1000Genomes
tmp_5_14008923_C_T 292 P>L No 1000Genomes
tmp_5_14008973_G_A 309 G>R No 1000Genomes
tmp_5_14008977_C_G 310 S>C No 1000Genomes
tmp_5_14009066_G_T 340 G>C No 1000Genomes
ENSVATH00675484 352 T>S No 1000Genomes
tmp_5_14009121_G_C 358 G>A No 1000Genomes
tmp_5_14009142_C_G 365 A>G No 1000Genomes
ENSVATH07219062 367 P>L No 1000Genomes
ENSVATH11978070 386 G>A No 1000Genomes
ENSVATH11978071 388 Q>K No 1000Genomes
ENSVATH11978105 409 S>N No 1000Genomes
tmp_5_14009300_A_T 418 N>Y No 1000Genomes
ENSVATH03246915 441 L>F No 1000Genomes
tmp_5_14009381_G_C 445 D>H No 1000Genomes
ENSVATH03246916 446 N>K No 1000Genomes
tmp_5_14009422_A_C 458 Q>H No 1000Genomes
ENSVATH03246917 461 D>H No 1000Genomes
tmp_5_14009444_G_T 466 V>F No 1000Genomes
tmp_5_14009457_A_C 470 H>P No 1000Genomes
ENSVATH03246921 505 S>T No 1000Genomes
ENSVATH07219063 506 E>Q No 1000Genomes
ENSVATH07219064 519 K>T No 1000Genomes
ENSVATH11978108 531 N>I No 1000Genomes
tmp_5_14009647_A_C 533 R>S No 1000Genomes
tmp_5_14009699_G_A 551 V>I No 1000Genomes
tmp_5_14009714_G_T 556 V>L No 1000Genomes
tmp_5_14009737_G_T 563 M>I No 1000Genomes
tmp_5_14009796_A_G 583 K>R No 1000Genomes
ENSVATH14520203 596 Q>R No 1000Genomes
tmp_5_14009861_G_A 605 V>M No 1000Genomes
ENSVATH14520204 639 T>I No 1000Genomes
tmp_5_14010050_G_T 668 A>S No 1000Genomes
ENSVATH11978110 672 E>K No 1000Genomes
ENSVATH11978111 677 R>L No 1000Genomes
tmp_5_14010253_A_T 690 R>W No 1000Genomes
ENSVATH14520235 699 V>F No 1000Genomes
tmp_5_14010287_C_T 701 T>I No 1000Genomes
ENSVATH14520236 720 D>N No 1000Genomes
tmp_5_14010346_G_T 721 V>F No 1000Genomes
ENSVATH03246929 723 G>D No 1000Genomes
ENSVATH00675493 726 T>K No 1000Genomes
tmp_5_14010367_A_G 728 T>A No 1000Genomes
ENSVATH00675494 735 K>Q No 1000Genomes
ENSVATH07219067 735 K>R No 1000Genomes
ENSVATH00675495 754 I>M No 1000Genomes
ENSVATH07219068 781 N>D No 1000Genomes
tmp_5_14010548_T_C 788 V>A No 1000Genomes
ENSVATH07219070 791 T>I No 1000Genomes
ENSVATH03246931 801 H>L No 1000Genomes
ENSVATH11978113 815 I>V No 1000Genomes
ENSVATH03246933 822 E>K No 1000Genomes
ENSVATH07219071 851 K>N No 1000Genomes
ENSVATH11978156 884 L>F No 1000Genomes
ENSVATH07219072 898 E>K No 1000Genomes
ENSVATH07219073 911 S>F No 1000Genomes
ENSVATH07219074 914 S>G No 1000Genomes
tmp_5_14010929_A_G 915 E>G No 1000Genomes
ENSVATH03246934 917 Q>H No 1000Genomes
ENSVATH11978157 935 I>L No 1000Genomes
ENSVATH00675499 940 I>M No 1000Genomes
tmp_5_14011129_A_G 949 E>G No 1000Genomes
ENSVATH00675503 951 D>G No 1000Genomes
ENSVATH11978160 1005 E>D No 1000Genomes
ENSVATH07219078 1006 T>S No 1000Genomes
tmp_5_14011320_T_C 1013 F>L No 1000Genomes
ENSVATH03246937 1017 L>W No 1000Genomes
ENSVATH03246938 1018 R>K No 1000Genomes
tmp_5_14011384_G_T 1034 G>V No 1000Genomes
ENSVATH07219080 1041 E>K No 1000Genomes
tmp_5_14011459_G_A 1059 R>K No 1000Genomes
tmp_5_14011506_G_A 1075 G>R No 1000Genomes
tmp_5_14011541_G_T 1086 M>I No 1000Genomes
ENSVATH11978196 1086 M>L No 1000Genomes
tmp_5_14011603_A_G 1107 E>G No 1000Genomes

No associated diseases with P14714

13 regional properties for P14714

Type Name Position InterPro Accession
domain PAS domain 604 - 730 IPR000014-1
domain PAS domain 737 - 860 IPR000014-2
repeat PAC motif 823 - 865 IPR001610
domain GAF domain 213 - 403 IPR003018
domain Histidine kinase/HSP90-like ATPase 994 - 1107 IPR003594
domain Histidine kinase domain 889 - 1111 IPR005467
domain Phytochrome, central region 406 - 580 IPR013515
binding_site Phytochrome chromophore binding site 313 - 322 IPR013516
domain PAS fold-2 65 - 180 IPR013654
domain PAS fold 607 - 721 IPR013767-1
domain PAS fold 737 - 860 IPR013767-2
domain Phytochrome chromophore attachment domain 213 - 383 IPR016132
domain Phytochrome A/B/C/D/E-like, histidine-kinase-related domain 993 - 1108 IPR044767

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
photoreceptor activity The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation.
protein homodimerization activity Binding to an identical protein to form a homodimer.

5 GO annotations of biological process

Name Definition
detection of visible light The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.
protein-tetrapyrrole linkage The covalent linking of a tetrapyrrole to a protein.
red, far-red light phototransduction The sequence of reactions within a cell required to convert absorbed photons from red or far-red light into a molecular signal; the red, far-red light range is defined as having a wavelength within the range 660-730 nm.
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
response to blue light Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P93528 PHYC Phytochrome C Sorghum bicolor (Sorghum) (Sorghum vulgare) PR
P14713 PHYB Phytochrome B Arabidopsis thaliana (Mouse-ear cress) PR
P42497 PHYD Phytochrome D Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MSSNTSRSCS TRSRQNSRVS SQVLVDAKLH GNFEESERLF DYSASINLNM PSSSCEIPSS
70 80 90 100 110 120
AVSTYLQKIQ RGMLIQPFGC LIVVDEKNLK VIAFSENTQE MLGLIPHTVP SMEQREALTI
130 140 150 160 170 180
GTDVKSLFLS PGCSALEKAV DFGEISILNP ITLHCRSSSK PFYAILHRIE EGLVIDLEPV
190 200 210 220 230 240
SPDEVPVTAA GALRSYKLAA KSISRLQALP SGNMLLLCDA LVKEVSELTG YDRVMVYKFH
250 260 270 280 290 300
EDGHGEVIAE CCREDMEPYL GLHYSATDIP QASRFLFMRN KVRMICDCSA VPVKVVQDKS
310 320 330 340 350 360
LSQPISLSGS TLRAPHGCHA QYMSNMGSVA SLVMSVTING SDSDEMNRDL QTGRHLWGLV
370 380 390 400 410 420
VCHHASPRFV PFPLRYACEF LTQVFGVQIN KEAESAVLLK EKRILQTQSV LCDMLFRNAP
430 440 450 460 470 480
IGIVTQSPNI MDLVKCDGAA LYYRDNLWSL GVTPTETQIR DLIDWVLKSH GGNTGFTTES
490 500 510 520 530 540
LMESGYPDAS VLGESICGMA AVYISEKDFL FWFRSSTAKQ IKWGGARHDP NDRDGKRMHP
550 560 570 580 590 600
RSSFKAFMEI VRWKSVPWDD MEMDAINSLQ LIIKGSLQEE HSKTVVDVPL VDNRVQKVDE
610 620 630 640 650 660
LCVIVNEMVR LIDTAAVPIF AVDASGVING WNSKAAEVTG LAVEQAIGKP VSDLVEDDSV
670 680 690 700 710 720
ETVKNMLALA LEGSEERGAE IRIRAFGPKR KSSPVELVVN TCCSRDMTNN VLGVCFIGQD
730 740 750 760 770 780
VTGQKTLTEN YSRVKGDYAR IMWSPSTLIP PIFITNENGV CSEWNNAMQK LSGIKREEVV
790 800 810 820 830 840
NKILLGEVFT TDDYGCCLKD HDTLTKLRIG FNAVISGQKN IEKLLFGFYH RDGSFIEALL
850 860 870 880 890 900
SANKRTDIEG KVTGVLCFLQ VPSPELQYAL QVQQISEHAI ACALNKLAYL RHEVKDPEKA
910 920 930 940 950 960
ISFLQDLLHS SGLSEDQKRL LRTSVLCREQ LAKVISDSDI EGIEEGYVEL DCSEFGLQES
970 980 990 1000 1010 1020
LEAVVKQVME LSIERKVQIS CDYPQEVSSM RLYGDNLRLQ QILSETLLSS IRFTPALRGL
1030 1040 1050 1060 1070 1080
CVSFKVIARI EAIGKRMKRV ELEFRIIHPA PGLPEDLVRE MFQPLRKGTS REGLGLHITQ
1090 1100 1110
KLVKLMERGT LRYLRESEMS AFVILTEFPL I