Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P10346

Entry ID Method Resolution Chain Position Source
AF-P10346-F1 Predicted AlphaFoldDB

No variants for P10346

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P10346

No associated diseases with P10346

1 regional properties for P10346

Type Name Position InterPro Accession
domain TauD/TfdA-like domain 7 - 272 IPR003819

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing A complex for the transport of metabolites into the cell, consisting of 5 subunits: two ATP-binding subunits, two membrane spanning subunits, and one substrate-binding subunit. In organisms with two membranes, the substrate-binding protein moves freely in the periplasmic space and joins the other subunits only when bound with substrate. In organisms with only one membrane the substrate-binding protein is tethered to the cytoplasmic membrane and associated with the other subunits. Transport of the substrate across the membrane is driven by the hydrolysis of ATP.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ABC-type amino acid transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(out/in) = ADP + phosphate + amino acid(in/out).
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

1 GO annotations of biological process

Name Definition
L-glutamine import across plasma membrane The directed movement of L-glutamine from outside of a cell, across the plasma membrane and into the cytosol.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P07109 hisP Histidine transport ATP-binding protein HisP Escherichia coli (strain K12) PR
P30750 metN Methionine import ATP-binding protein MetN Escherichia coli (strain K12) PR
P37774 tcyN L-cystine transport system ATP-binding protein TcyN Escherichia coli (strain K12) PR
10 20 30 40 50 60
MIEFKNVSKH FGPTQVLHNI DLNIAQGEVV VIIGPSGSGK STLLRCINKL EEITSGDLIV
70 80 90 100 110 120
DGLKVNDPKV DERLIRQEAG MVFQQFYLFP HLTALENVMF GPLRVRGANK EEAEKLAREL
130 140 150 160 170 180
LAKVGLAERA HHYPSELSGG QQQRVAIARA LAVKPKMMLF DEPTSALDPE LRHEVLKVMQ
190 200 210 220 230
DLAEEGMTMV IVTHEIGFAE KVASRLIFID KGRIAEDGNP QVLIKNPPSQ RLQEFLQHVS