P0CG08
PR
Gene name |
GPR89B (GPHRB, GPR89C, HSPC201) |
Protein name |
Golgi pH regulator B |
Names |
Protein GPR89B |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:653519 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P0CG08
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P0CG08-F1 | Predicted | AlphaFoldDB |
210 variants for P0CG08
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs377651969 CA29913319 |
5 | I>N | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA1066206 rs781949323 |
6 | D>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1066205 rs140594340 |
6 | D>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1231307317 CA342215453 |
7 | S>P | No |
ClinGen TOPMed |
|
|
CA342215464 rs1319907049 |
8 | S>G | No |
ClinGen TOPMed |
|
|
CA342215501 rs782226540 |
10 | M>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA342215510 rs1553246487 |
10 | M>T | No |
ClinGen gnomAD |
|
|
CA1066207 rs782226540 |
10 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1359299720 CA342215546 |
12 | T>I | No |
ClinGen TOPMed gnomAD |
|
|
rs1571205251 CA342215539 |
12 | T>P | No |
ClinGen Ensembl |
|
| TCGA novel | 13 | S>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA1066208 rs782371724 |
13 | S>T | No |
ClinGen ExAC gnomAD |
|
|
rs1571205298 CA342215561 |
13 | S>Y | No |
ClinGen Ensembl |
|
|
rs368374809 CA1066228 |
15 | I>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA342216403 rs1485592330 |
15 | I>V | No |
ClinGen TOPMed |
|
|
CA1066229 rs587632867 |
16 | L>P | No |
ClinGen 1000Genomes ExAC gnomAD |
|
| TCGA novel | 18 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| rs1351486989 | 19 | G>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1260255598 CA342216435 |
20 | F>L | No |
ClinGen TOPMed |
|
|
CA1066230 rs782184239 |
22 | W>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA342216460 rs1553247955 |
23 | L>F | No |
ClinGen gnomAD |
|
|
CA342216471 rs1342505755 COSM1294958 |
24 | F>L | Variant assessed as Somatic; impact. urinary_tract [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
rs1553247959 CA342216488 |
26 | M>I | No |
ClinGen gnomAD |
|
|
rs587718844 CA1066231 |
27 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
rs781958553 CA1066232 |
27 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs587718844 CA342216489 |
27 | R>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA342216543 rs1553247974 |
33 | Y>* | No |
ClinGen gnomAD |
|
| TCGA novel | 34 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA29915773 rs200669915 |
35 | I>M | No |
ClinGen Ensembl |
|
|
rs781906653 CA1066245 |
36 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs587629056 CA1066246 |
36 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA342216587 rs1553248395 |
37 | Q>H | No |
ClinGen gnomAD |
|
|
rs782588706 CA1066247 |
38 | Y>S | No |
ClinGen ExAC gnomAD |
|
|
rs201862480 CA1066248 |
41 | Q>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1553248401 CA342216628 |
44 | F>L | No |
ClinGen gnomAD |
|
|
CA1066251 rs782632071 |
46 | V>M | No |
ClinGen ExAC gnomAD |
|
|
rs375851990 CA1066252 |
47 | T>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs782408142 CA1066253 |
48 | F>L | No |
ClinGen ExAC gnomAD |
|
|
rs781913248 CA1066254 |
49 | A>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs782193444 CA1066255 |
53 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA342216698 CA342216700 rs1553248415 |
54 | M>I | No |
ClinGen gnomAD |
|
|
CA342216715 rs1553248417 |
56 | E>D | No |
ClinGen gnomAD |
|
|
rs1357293281 CA342216721 |
57 | L>P | No |
ClinGen TOPMed gnomAD |
|
|
CA342216725 rs1394933892 |
58 | I>L | No |
ClinGen TOPMed |
|
|
CA342216731 rs1399518858 |
59 | I>V | No |
ClinGen TOPMed |
|
|
rs1457463831 CA342216773 |
65 | V>I | No |
ClinGen TOPMed gnomAD |
|
|
rs781968148 CA1066257 |
67 | N>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs782001707 CA1066275 |
70 | S>F | No |
ClinGen ExAC gnomAD |
|
|
rs782272012 CA1066276 |
71 | R>C | No |
ClinGen ExAC gnomAD |
|
|
CA1066277 rs782414733 |
71 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA342216847 rs1197756841 |
72 | Y>C | No |
ClinGen TOPMed |
|
|
TCGA novel rs1553249209 CA342216880 |
75 | W>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
NCI-TCGA ClinGen gnomAD |
|
CA342216874 rs1553249207 |
75 | W>R | No |
ClinGen gnomAD |
|
|
rs782064435 CA342216936 |
79 | L>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs782064435 CA1066279 |
79 | L>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs142935665 CA342216948 |
80 | C>W | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA1066281 rs375267760 |
82 | I>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs782121023 CA1066282 |
84 | L>V | No |
ClinGen ExAC gnomAD |
|
|
rs139258514 CA1066283 |
89 | M>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA342217047 rs1258024168 |
91 | P>T | No |
ClinGen TOPMed |
|
|
rs1553249236 CA342217064 |
92 | F>L | No |
ClinGen gnomAD |
|
|
rs1194128331 CA342217061 |
92 | F>S | No |
ClinGen TOPMed |
|
|
CA342217073 rs1553249238 |
93 | Y>C | No |
ClinGen gnomAD |
|
|
rs781891808 CA1066285 |
95 | G>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1066286 rs782570069 |
96 | Y>C | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 96 | Y>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 96 | Y>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA342217114 rs1553249255 |
97 | F>I | No |
ClinGen gnomAD |
|
|
CA1066288 rs781878942 |
100 | S>R | No |
ClinGen ExAC gnomAD |
|
|
CA342217170 rs1368446714 |
102 | I>V | No |
ClinGen TOPMed |
|
|
CA1066289 rs145261510 |
103 | R>* | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA342217186 rs782621260 |
103 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1066290 rs782621260 |
103 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA342217192 rs782459478 |
104 | L>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs782459478 CA1066292 |
104 | L>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs370678417 CA342217195 |
105 | L>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA342217254 rs1217555015 |
106 | H>P | No |
ClinGen TOPMed |
|
|
rs1359393049 CA342217280 |
108 | Q>* | No |
ClinGen TOPMed |
|
|
rs1359393049 CA342217277 |
108 | Q>K | No |
ClinGen TOPMed |
|
|
rs782210342 CA1066318 |
108 | Q>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1066319 rs143821798 |
109 | R>* | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA1066320 rs782562694 |
109 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs782401775 CA1066324 |
113 | S>P | No |
ClinGen ExAC gnomAD |
|
|
rs1403166719 CA342217351 |
117 | W>* | No |
ClinGen TOPMed |
|
|
rs782342661 CA1066327 |
117 | W>L | No |
ClinGen ExAC gnomAD |
|
|
rs781943877 CA1066328 |
118 | L>P | No |
ClinGen ExAC gnomAD |
|
|
CA1066329 rs782055663 |
119 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs1571236950 CA342217391 |
121 | M>L | No |
ClinGen Ensembl |
|
|
CA342217395 rs1417566360 |
121 | M>T | No |
ClinGen TOPMed gnomAD |
|
|
CA1066332 rs587766922 |
123 | F>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA1066331 rs781888365 |
123 | F>V | No |
ClinGen ExAC gnomAD |
|
|
rs201402961 CA1066334 |
128 | G>* | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA342217482 rs1553249406 |
128 | G>E | No |
ClinGen gnomAD |
|
|
CA342218312 rs1478361598 |
143 | I>V | No |
ClinGen TOPMed |
|
| TCGA novel | 144 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1275679187 CA342218426 |
149 | R>Q | No |
ClinGen TOPMed |
|
|
rs1484140509 CA342218424 |
149 | R>W | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA342218459 rs1203540950 |
151 | G>R | No |
ClinGen TOPMed |
|
|
rs1303245787 CA342218510 |
153 | I>T | No |
ClinGen TOPMed |
|
|
CA342218650 rs1366241609 |
161 | L>I | No |
ClinGen TOPMed |
|
|
rs1366241609 CA342218653 |
161 | L>V | No |
ClinGen TOPMed |
|
|
CA342218783 rs1350720653 |
168 | N>S | No |
ClinGen TOPMed |
|
|
rs1461736582 CA342218828 |
172 | T>A | No |
ClinGen TOPMed |
|
|
rs1353130532 CA342218834 |
172 | T>I | No |
ClinGen TOPMed |
|
|
rs1178804540 CA342218864 |
174 | M>L | No |
ClinGen TOPMed |
|
|
rs1415575711 CA342218886 |
174 | M>T | No |
ClinGen TOPMed |
|
|
CA342219066 rs1390794839 |
179 | R>S | No |
ClinGen TOPMed |
|
|
CA342219164 rs1318386249 |
184 | T>M | No |
ClinGen TOPMed |
|
|
CA342219239 rs1405342799 |
189 | L>V | No |
ClinGen TOPMed |
|
|
rs1164643710 CA342219253 |
190 | E>Q | No |
ClinGen TOPMed |
|
|
rs1386273583 CA342219278 |
191 | R>Q | No |
ClinGen TOPMed |
|
|
CA342219271 rs1446765212 |
191 | R>W | No |
ClinGen TOPMed |
|
|
rs1183475272 CA342219287 |
192 | R>Q | No |
ClinGen TOPMed |
|
|
rs1250503913 CA342219321 |
194 | L>P | No |
ClinGen TOPMed |
|
|
rs1553251401 CA342219331 |
195 | Q>* | No |
ClinGen Ensembl |
|
|
CA342219374 rs1216584124 |
197 | M>V | No |
ClinGen TOPMed |
|
|
CA342219433 rs1446503249 |
199 | M>V | No |
ClinGen TOPMed |
|
|
rs1282349689 CA342219540 |
204 | K>M | No |
ClinGen TOPMed |
|
|
rs1370082651 CA342219741 |
208 | A>T | No |
ClinGen TOPMed |
|
|
rs1323810434 CA342219758 |
209 | M>V | No |
ClinGen TOPMed |
|
|
CA342219806 rs1448345482 |
210 | A>T | No |
ClinGen TOPMed |
|
|
rs1169284223 CA342219824 |
211 | R>Q | No |
ClinGen TOPMed |
|
|
CA342219823 rs1354668985 |
211 | R>W | No |
ClinGen TOPMed |
|
|
rs1571285823 CA342219854 |
213 | T>K | No |
ClinGen Ensembl |
|
|
CA342219860 rs1407899085 |
214 | M>V | No |
ClinGen TOPMed |
|
|
rs1426867703 CA342219921 |
217 | K>E | No |
ClinGen TOPMed |
|
|
rs1454993389 CA342220008 |
220 | V>M | No |
ClinGen TOPMed |
|
|
CA342220038 rs1252848773 |
221 | H>R | No |
ClinGen TOPMed |
|
|
rs1203947122 CA342220117 |
226 | G>D | No |
ClinGen TOPMed |
|
|
rs1305930899 CA342220250 |
235 | T>I | No |
ClinGen TOPMed |
|
|
CA342220415 rs1209430990 |
245 | T>A | No |
ClinGen TOPMed |
|
|
rs1328664982 CA342220419 |
245 | T>I | No |
ClinGen TOPMed |
|
| TCGA novel | 249 | Q>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA342220481 rs1266439835 |
250 | E>K | No |
ClinGen TOPMed |
|
|
rs1235423622 CA342220491 |
251 | V>L | No |
ClinGen TOPMed |
|
| TCGA novel | 256 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1242345523 CA342220647 |
261 | L>F | No |
ClinGen TOPMed |
|
|
rs1328068744 CA342220706 |
265 | T>I | No |
ClinGen TOPMed |
|
|
rs1321204194 CA342220742 |
268 | L>V | No |
ClinGen TOPMed |
|
|
CA342220778 rs1385850178 |
271 | T>S | No |
ClinGen TOPMed |
|
| TCGA novel | 273 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1386375722 CA342220847 |
274 | R>G | No |
ClinGen TOPMed |
|
|
CA342221006 rs1309550047 |
284 | K>R | No |
ClinGen TOPMed |
|
| TCGA novel | 291 | Y>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA342221285 rs1369858400 |
297 | C>R | No |
ClinGen TOPMed |
|
| TCGA novel | 301 | I>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1282711781 CA342388357 |
304 | A>T | No |
ClinGen TOPMed |
|
|
rs1434489339 CA342388372 |
305 | T>A | No |
ClinGen TOPMed |
|
|
rs1337618514 CA342388382 |
305 | T>I | No |
ClinGen TOPMed |
|
|
CA342388387 rs1409634730 |
306 | I>V | No |
ClinGen TOPMed |
|
|
CA342388471 rs1394022912 |
310 | F>L | No |
ClinGen TOPMed |
|
| TCGA novel | 310 | F>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 312 | R>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1470231180 CA342388486 |
312 | R>G | No |
ClinGen TOPMed |
|
|
rs1428579054 CA342388489 |
312 | R>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA342388496 rs1173624652 |
313 | V>I | No |
ClinGen TOPMed |
|
|
CA342388546 rs1470841095 |
316 | T>M | No |
ClinGen TOPMed |
|
| TCGA novel | 318 | P>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1180586706 CA342388576 |
318 | P>S | No |
ClinGen TOPMed |
|
|
rs1435749018 CA342388609 |
321 | R>G | No |
ClinGen TOPMed |
|
|
CA342388619 rs1236708314 |
321 | R>K | No |
ClinGen TOPMed |
|
| TCGA novel | 324 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA342388679 rs1206032855 |
325 | I>N | No |
ClinGen TOPMed |
|
|
CA342388696 rs1324884811 |
326 | T>I | No |
ClinGen TOPMed |
|
|
CA342388762 rs1262993666 |
332 | I>L | No |
ClinGen TOPMed |
|
| TCGA novel | 334 | F>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1571317998 CA342388809 |
335 | D>G | No |
ClinGen Ensembl |
|
| TCGA novel | 336 | V>= | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA342388868 rs1571321015 |
336 | V>G | No |
ClinGen Ensembl |
|
|
rs1571321038 CA342388872 |
337 | K>E | No |
ClinGen Ensembl |
|
|
rs1571321049 CA342388894 |
338 | F>V | No |
ClinGen Ensembl |
|
|
CA342388926 rs1571321064 |
339 | W>L | No |
ClinGen Ensembl |
|
|
rs1571321073 CA342388961 |
341 | Q>P | No |
ClinGen Ensembl |
|
| TCGA novel | 344 | S>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1345822110 CA342389012 |
347 | L>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs1232408944 CA342389053 |
350 | I>L | No |
ClinGen TOPMed |
|
|
rs1309770487 CA342389094 |
353 | V>I | No |
ClinGen TOPMed |
|
|
rs1336093538 CA342389226 |
362 | T>I | No |
ClinGen TOPMed |
|
|
CA342389237 rs1414486859 |
363 | L>P | No |
ClinGen TOPMed |
|
| TCGA novel | 366 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 366 | F>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 367 | F>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1450581397 CA342389408 |
370 | I>N | No |
ClinGen TOPMed |
|
|
rs1390864390 CA342389508 |
377 | N>I | No |
ClinGen TOPMed |
|
|
rs1390864390 CA342389506 |
377 | N>S | No |
ClinGen TOPMed |
|
|
CA342389608 rs1383064201 |
385 | Q>E | No |
ClinGen TOPMed |
|
| TCGA novel | 386 | I>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 387 | M>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 388 | G>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1405767511 CA342389701 |
389 | M>T | No |
ClinGen TOPMed |
|
|
CA342389829 rs1431622964 |
398 | I>M | No |
ClinGen TOPMed |
|
|
rs1390700022 CA342389835 |
399 | R>* | No |
ClinGen TOPMed |
|
|
CA342389838 rs1187442634 |
399 | R>Q | No |
ClinGen TOPMed |
|
|
rs1474122461 CA342389848 |
400 | M>V | No |
ClinGen TOPMed |
|
|
rs1248125572 CA342389950 |
406 | Y>H | No |
ClinGen TOPMed |
|
|
rs1199071684 CA342389964 |
407 | R>H | No |
ClinGen TOPMed |
|
|
rs1345007953 CA342390197 |
422 | Y>C | No |
ClinGen TOPMed |
|
|
CA342390215 rs1275937732 |
423 | H>Y | No |
ClinGen TOPMed |
|
| TCGA novel | 424 | R>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA342390229 rs1214095301 |
424 | R>H | No |
ClinGen TOPMed |
|
|
rs1345113313 CA342390328 |
432 | V>F | No |
ClinGen TOPMed |
|
|
CA342390355 rs1411405134 |
434 | A>T | No |
ClinGen TOPMed |
|
|
rs1371129700 CA342390361 |
434 | A>V | No |
ClinGen TOPMed |
|
|
CA342390416 rs1407735604 |
438 | I>M | No |
ClinGen TOPMed |
|
|
rs1426587953 CA342390418 |
439 | L>V | No |
ClinGen TOPMed |
|
| TCGA novel | 442 | Y>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA342390645 rs1172801763 |
452 | Q>E | No |
ClinGen TOPMed |
|
|
CA342390697 rs1479942345 |
454 | A>V | No |
ClinGen TOPMed |
|
|
rs1266308131 CA342390701 |
455 | P>A | No |
ClinGen TOPMed |
|
|
CA342390719 rs1197773022 |
456 | P>C | No |
ClinGen TOPMed |
No associated diseases with P0CG08
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| Golgi cisterna membrane | The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| voltage-gated anion channel activity | Enables the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| intracellular pH reduction | Any process that reduces the internal pH of a cell, measured by the concentration of the hydrogen ion. |
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| regulation of ion transmembrane transport | Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. |
| T cell differentiation | The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P38799 | YHR078W | Uncharacterized protein YHR078W | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q5BIM9 | GPR89 | Golgi pH regulator | Bos taurus (Bovine) | PR |
| Q5F448 | GPR89 | Golgi pH regulator | Gallus gallus (Chicken) | PR |
| B7ZAQ6 | GPR89A | Golgi pH regulator A | Homo sapiens (Human) | PR |
| Q8BS95 | Gpr89 | Golgi pH regulator | Mus musculus (Mouse) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSFLIDSSIM | ITSQILFFGF | GWLFFMRQLF | KDYEIRQYVV | QVIFSVTFAF | SCTMFELIIF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EILGVLNSSS | RYFHWKMNLC | VILLILVFMV | PFYIGYFIVS | NIRLLHKQRL | LFSCLLWLTF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MYFFWKLGDP | FPILSPKHGI | LSIEQLISRV | GVIGVTLMAL | LSGFGAVNCP | YTYMSYFLRN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VTDTDILALE | RRLLQTMDMI | ISKKKRMAMA | RRTMFQKGEV | HNKPSGFWGM | IKSVTTSASG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SENLTLIQQE | VDALEELSRQ | LFLETADLYA | TKERIEYSKT | FKGKYFNFLG | YFFSIYCVWK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IFMATINIVF | DRVGKTDPVT | RGIEITVNYL | GIQFDVKFWS | QHISFILVGI | IIVTSIRGLL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ITLTKFFYAI | SSSKSSNVIV | LLLAQIMGMY | FVSSVLLIRM | SMPLEYRTII | TEVLGELQFN |
| 430 | 440 | 450 | |||
| FYHRWFDVIF | LVSALSSILF | LYLAHKQAPE | KQMAP |