Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P07153
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P07153-F1 | Predicted | AlphaFoldDB |
No variants for P07153
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P07153 | |||||
No associated diseases with P07153
No regional properties for P07153
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P07153 | |||
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| melanosome | A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells. |
| oligosaccharyltransferase complex | A protein complex that is found in the endoplasmic reticulum membrane of eukaryotes and transfers lipid-linked oligosaccharide precursor to asparagine residues on nascent proteins. In yeast, the complex includes at least nine different subunits, whereas in mammalian cells at least three different forms of the complex have been detected. |
| rough endoplasmic reticulum | The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| peptide transport | The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| protein N-linked glycosylation | A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan. |
| protein N-linked glycosylation via asparagine | The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification. |
4 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P04843 | RPN1 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 | Homo sapiens (Human) | PR |
| Q91YQ5 | Rpn1 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 | Mus musculus (Mouse) | PR |
| Q9GMB0 | RPN1 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 | Sus scrofa (Pig) | PR |
| Q0DJC5 | OST1A | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1A | Oryza sativa subsp japonica (Rice) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEAPIVLLLL | LWLALAPTPG | SASSEAPPLV | NEDVKRTVDL | SSHLAKVTAE | VVLAHPGGGS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TARASSFVLA | LEPELESRLA | HLGVQVKGED | EEDNNLEVRE | TKMKGKSGRF | FTVKLPVALD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PGSKISIVVE | TVYTHVLHPY | PTQITQSEKQ | FVVFEGNHYF | YSPYPTKTQT | MRVRLASRNV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ESHTKLGNPS | RSEDILDYGP | FKDIPAYSQD | TFKVHYENNS | PFLTITSMTR | VIEVSHWGNI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AVEENVDLKH | TGAVLKGPFS | RYDYQRQPDS | GISSIRSFKT | ILPAAAQDVY | YRDEIGNVST |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SHLLILDDSV | EMEIRPRFGL | FGGWKTHYIV | GYNLPSYEYL | YNLGDQYALK | MRFVDHVFDE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| QVIDSLTVKI | ILPEGAKNIQ | VDSPYDISRA | PDELHYTYLD | TFGRPVIVAY | KKNLVEQHIQ |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DIVVHYTFNK | VLMLQEPLLV | VAAFYILFFT | VIIYVRLDFS | ITKDPAAEAR | MKVACITEQV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LTLVNKRLGL | YRHFDETVNR | YKQSRDISTL | NSGKKSLETE | HKAVTSEIAV | LQSRLKTEGS |
| 550 | 560 | 570 | 580 | 590 | 600 |
| DLCDRVSEMQ | KLDAQVKELV | LKSAVEAERL | VAGKLKKDTY | IENEKLSSGK | RQELVTKIDH |
| ILDAL |