O97596

PR
Gene name
Slc20a1 (Pit1)
Protein name
Sodium-dependent phosphate transporter 1
Names
Feline leukemia virus subtype-B receptor, Phosphate transporter 1, PiT-1, Solute carrier family 20 member 1
Species
Felis catus (Cat) (Felis silvestris catus)
KEGG Pathway
fca:493789
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

236-370 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O97596

Entry ID Method Resolution Chain Position Source
AF-O97596-F1 Predicted AlphaFoldDB

No variants for O97596

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O97596

No associated diseases with O97596

No regional properties for O97596

Type Name Position InterPro Accession
No domain, repeats, and functional sites for O97596

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
inorganic phosphate transmembrane transporter activity Enables the transfer of a inorganic phosphate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
symporter activity Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.

1 GO annotations of biological process

Name Definition
phosphate ion transmembrane transport The process in which a phosphate is transported across a membrane.

5 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q95L97 SLC20A2 Sodium-dependent phosphate transporter 2 Felis catus (Cat) (Felis silvestris catus) PR
Q08357 SLC20A2 Sodium-dependent phosphate transporter 2 Homo sapiens (Human) PR
Q8WUM9 SLC20A1 Sodium-dependent phosphate transporter 1 Homo sapiens (Human) PR
Q61609 Slc20a1 Sodium-dependent phosphate transporter 1 Mus musculus (Mouse) PR
Q5BL44 slc20a1 Sodium-dependent phosphate transporter 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
10 20 30 40 50 60
MAFTGATLTT STIAATAASG PLMDYLWMLI LGFIIAFVLA FSVGANDVAN SFGTAVGSGV
70 80 90 100 110 120
VTLKQACILA SIFETVGSVL LGAKVSETIR KGLIDVEMYN TTQQLLMAGS VSAMFGSAVW
130 140 150 160 170 180
QLVASFLKLP ISGTHCIVGA TIGFSLVAKG QEGVKWSELI KIVMSWFISP LLSGIMSGIL
190 200 210 220 230 240
FFLVRAFILR KTDPVPNGLR ALPVFYACTV GINLFSIMYT GAPLLGFDKL PLWGTILISV
250 260 270 280 290 300
GCAVFCALIV WFFVCPRMKR KIEREIKSSP SESPLMEKKN SLKEDHEETK LSVSDIETRS
310 320 330 340 350 360
PVSEVGSATV PLRAVVEERT VSFKLGDLEE APERERLPSV DLKEETSIDS AMNGAVQLPN
370 380 390 400 410 420
GNLVQFNQAV SNQMNSSGHY QYHTVHKDSG LYKELLHKLH LAKVGDCMGD SGDKPLRRNN
430 440 450 460 470 480
SYTSYTMAIC GMPLDSFRAK EGEQKGEEME KLTWPNAESK KRIRMDSYTS YCNAVSDIHS
490 500 510 520 530 540
ASEMDMSVKA EMGLGDRKGS SSSLEEWYDQ DKPEVSLLFQ FLQILTACFG SFAHGGNDVS
550 560 570 580 590 600
NAIGPLVALY LVYDTGDVSS KVATPIWLLL YGGVGICIGL WVWGRRVIQT MGKDLTPITP
610 620 630 640 650 660
SSGFSIELAS ALTVVIASNI GLPISTTHCK VGSVVSVGWL RSKKAVDWRL FRNIFMAWFV
670 680
TVPISGVISA AIMAVFKYVI L