O81123

PR
Gene name
ZIP1 (At3g12750, MBK21.13)
Protein name
Zinc transporter 1
Names
ZRT/IRT-like protein 1
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT3G12750
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

130-208 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O81123

Entry ID Method Resolution Chain Position Source
AF-O81123-F1 Predicted AlphaFoldDB

15 variants for O81123

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH10637120 5 G>R No 1000Genomes
tmp_3_4053132_C_T 9 A>T No 1000Genomes
tmp_3_4053096_T_A 21 I>L No 1000Genomes
ENSVATH10637118 29 S>W No 1000Genomes
tmp_3_4052979_C_T 60 V>I No 1000Genomes
tmp_3_4052834_G_C 108 A>G No 1000Genomes
ENSVATH00319657 179 I>V No 1000Genomes
tmp_3_4052606_C_G 184 S>T No 1000Genomes
ENSVATH05817368 213 V>A No 1000Genomes
ENSVATH00319656 224 S>R No 1000Genomes
ENSVATH05817367 226 D>Y No 1000Genomes
ENSVATH02137344 273 L>F No 1000Genomes
tmp_3_4052170_C_T 283 S>N No 1000Genomes
ENSVATH05817363 317 L>I No 1000Genomes
tmp_3_4052016_G_T 334 H>Q No 1000Genomes

No associated diseases with O81123

No regional properties for O81123

Type Name Position InterPro Accession
No domain, repeats, and functional sites for O81123

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
zinc ion transmembrane transporter activity Enables the transfer of zinc (Zn) ions from one side of a membrane to the other.

1 GO annotations of biological process

Name Definition
zinc ion transmembrane transport A process in which a zinc II ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q940Q3 ZTP29 Zinc transporter ZTP29 Arabidopsis thaliana (Mouse-ear cress) PR
O23039 ZIP5 Zinc transporter 5 Arabidopsis thaliana (Mouse-ear cress) PR
P59889 slc39a1 Zinc transporter ZIP1 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MSECGCFSAT TMLRICVVLI ICLHMCCASS DCTSHDDPVS QDEAEKATKL KLGSIALLLV
70 80 90 100 110 120
AGGVGVSLPL IGKRIPALQP ENDIFFMVKA FAAGVILCTG FVHILPDAFE RLSSPCLEDT
130 140 150 160 170 180
TAGKFPFAGF VAMLSAMGTL MIDTFATGYY KRQHFSNNHG SKQVNVVVDE EEHAGHVHIH
190 200 210 220 230 240
THASHGHTHG STELIRRRIV SQVLEIGIVV HSVIIGISLG ASQSIDTIKP LMAALSFHQF
250 260 270 280 290 300
FEGLGLGGCI SLADMKSKST VLMATFFSVT APLGIGIGLG MSSGLGYRKE SKEAIMVEGM
310 320 330 340 350
LNAASAGILI YMSLVDLLAT DFMNPRLQSN LWLHLAAYLS LVLGAGSMSL LAIWA