O23039

PR
Gene name
ZIP5 (At1g05300, YUP8H12.8)
Protein name
Zinc transporter 5
Names
ZRT/IRT-like protein 5
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT1G05300
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

123-227 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O23039

Entry ID Method Resolution Chain Position Source
AF-O23039-F1 Predicted AlphaFoldDB

24 variants for O23039

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_1_1547703_T_C 3 I>V No 1000Genomes
tmp_1_1547675_A_C 12 F>C No 1000Genomes
tmp_1_1547676_A_G 12 F>L No 1000Genomes
ENSVATH04523434 14 F>V No 1000Genomes
ENSVATH13854418 31 C>* No 1000Genomes
tmp_1_1547601_C_A 37 D>Y No 1000Genomes
ENSVATH04523433 40 A>E No 1000Genomes
tmp_1_1547583_C_A 43 A>S No 1000Genomes
ENSVATH00006858 46 K>R No 1000Genomes
ENSVATH04523432 51 A>T No 1000Genomes
tmp_1_1547538_C_T 58 A>T No 1000Genomes
ENSVATH04523431 74 P>S No 1000Genomes
ENSVATH04523430 75 S>L No 1000Genomes
ENSVATH13854416 131 V>A No 1000Genomes
tmp_1_1547319_C_A 131 V>F No 1000Genomes
tmp_1_1547295_C_T 139 V>I No 1000Genomes
ENSVATH01014946 150 A>S No 1000Genomes
ENSVATH04523428 175 E>D No 1000Genomes
tmp_1_1547157_G_A 185 H>Y No 1000Genomes
tmp_1_1546244_C_T 241 A>T No 1000Genomes
ENSVATH13854412 254 G>V No 1000Genomes
tmp_1_1546194_G_C 257 I>M No 1000Genomes
ENSVATH01014916 265 M>V No 1000Genomes
tmp_1_1545421_T_C 307 N>S No 1000Genomes

No associated diseases with O23039

No regional properties for O23039

Type Name Position InterPro Accession
No domain, repeats, and functional sites for O23039

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
zinc ion transmembrane transporter activity Enables the transfer of zinc (Zn) ions from one side of a membrane to the other.

1 GO annotations of biological process

Name Definition
zinc ion transmembrane transport A process in which a zinc II ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O81123 ZIP1 Zinc transporter 1 Arabidopsis thaliana (Mouse-ear cress) PR
Q940Q3 ZTP29 Zinc transporter ZTP29 Arabidopsis thaliana (Mouse-ear cress) PR
P59889 slc39a1 Zinc transporter ZIP1 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MRITQNVKLL LFFFFFISFL FIAVSAGESK CECSHEDDEA NKAGAKKYKI AAIPSVLAAG
70 80 90 100 110 120
VIGVMFPLLG KFFPSLKPET TFFFVTKAFA AGVILATGFM HVLPEGYEKL TSPCLKGEAW
130 140 150 160 170 180
EFPFTGFIAM VAAILTLSVD SFATSYFHKA HFKTSKRIGD GEEQDAGGGG GGGDELGLHV
190 200 210 220 230 240
HAHGHTHGIV GVESGESQVQ LHRTRVVAQV LEVGIIVHSV VIGISLGASQ SPDTAKALFA
250 260 270 280 290 300
ALMFHQCFEG LGLGGCIAQG NFNCMSITIM SIFFSVTTPV GIAVGMAISS SYDDSSPTAL
310 320 330 340 350
IVQGVLNAAS AGILIYMSLV DFLAADFMHP KMQSNTRLQI MAHISLLVGA GVMSLLAKWA