Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O35824
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O35824-F1 | Predicted | AlphaFoldDB |
No variants for O35824
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O35824 | |||||
No associated diseases with O35824
6 regional properties for O35824
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | TGS | 288 - 363 | IPR004095 |
| domain | Small GTP-binding protein domain | 62 - 213 | IPR005225 |
| domain | GTP binding domain | 64 - 166 | IPR006073 |
| conserved_site | GTP1/OBG, conserved site | 115 - 128 | IPR006074 |
| domain | OBG-type guanine nucleotide-binding (G) domain | 63 - 288 | IPR031167 |
| domain | GTP binding protein, second domain | 185 - 289 | IPR031662 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
6 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATPase activator activity | Binds to and increases the activity of an ATP hydrolysis activity. |
| chaperone binding | Binding to a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport. |
| Hsp70 protein binding | Binding to a Hsp70 protein, heat shock proteins around 70kDa in size. |
| metal ion binding | Binding to a metal ion. |
| unfolded protein binding | Binding to an unfolded protein. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| carbon tetrachloride metabolic process | The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants. |
| protein refolding | The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones. |
| response to heat | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MANVADTKLY | DILGVPPGAS | ENELKKAYRK | LAKEYHPDKN | PNAGDKFKEI | SFAYEVLSNP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EKRELYDRYG | EQGLREGSGG | GGGMDDIFSH | IFGGGLFGFM | GNQSRSRNGR | RRGEDMMHPL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KVSLEDLYNG | KTTKLQLSKN | VLCSACSGQG | GKSGAVQKCS | ACRGRGVRIM | IRQLAPGMVQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QMQSVCSDCN | GEGEVINEKD | RCKKCEGKKV | IKEVKILEVH | VDKGMKHGQR | ITFTGEADQA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PGVEPGDIVL | FVQEKEHEVF | QRDGNDLHMT | YKIGLVEALC | GFQFTFKHLD | ARQIVVKYPP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GKVIEPGCVR | VVRGEGMPQY | RNPFEKGDLY | IKFDVQFPEN | NWINPDKLSE | LEDLLPSRPE |
| 370 | 380 | 390 | 400 | 410 | |
| VPNVIGETEE | VELQEFDSTR | GSGGGQRREA | YNDSSDEESS | SHHGPGVQCA | HQ |