F4J738
Gene name |
At3g59020 (F17J16.70) |
Protein name |
Importin beta-like SAD2 homolog |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G59020 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for F4J738
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-F4J738-F1 | Predicted | AlphaFoldDB |
50 variants for F4J738
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_3_21817054_C_T | 50 | G>S | No | 1000Genomes | |
| ENSVATH02523605 | 74 | H>L | No | 1000Genomes | |
| ENSVATH06341159 | 79 | N>D | No | 1000Genomes | |
| tmp_3_21816817_C_A | 100 | V>L | No | 1000Genomes | |
| ENSVATH06341154 | 121 | P>L | No | 1000Genomes | |
| tmp_3_21816516_C_G | 132 | K>N | No | 1000Genomes | |
| ENSVATH12827462 | 137 | K>N | No | 1000Genomes | |
| tmp_3_21816503_T_G | 137 | K>Q | No | 1000Genomes | |
| tmp_3_21815837_C_G | 184 | V>L | No | 1000Genomes | |
| tmp_3_21815565_T_G | 218 | D>A | No | 1000Genomes | |
| ENSVATH12827439 | 241 | G>R | No | 1000Genomes | |
| ENSVATH02523594 | 247 | E>G | No | 1000Genomes | |
| ENSVATH12827423 | 332 | K>E | No | 1000Genomes | |
| tmp_3_21814765_T_G | 337 | N>T | No | 1000Genomes | |
| tmp_3_21814745_T_G | 344 | N>H | No | 1000Genomes | |
| ENSVATH12827422 | 368 | D>N | No | 1000Genomes | |
| ENSVATH00426954 | 408 | K>R | No | 1000Genomes | |
| ENSVATH12827421 | 421 | N>Y | No | 1000Genomes | |
| ENSVATH02523586 | 425 | L>M | No | 1000Genomes | |
| ENSVATH12827420 | 426 | E>K | No | 1000Genomes | |
| tmp_3_21813795_G_A | 481 | A>V | No | 1000Genomes | |
| ENSVATH02523584 | 496 | S>C | No | 1000Genomes | |
| tmp_3_21813746_A_T | 497 | N>K | No | 1000Genomes | |
| ENSVATH12827418 | 503 | H>N | No | 1000Genomes | |
| ENSVATH06341108 | 527 | F>Y | No | 1000Genomes | |
| tmp_3_21813147_C_T | 599 | G>S | No | 1000Genomes | |
| ENSVATH14453635 | 644 | R>Q | No | 1000Genomes | |
| ENSVATH06341096 | 694 | F>I | No | 1000Genomes | |
| tmp_3_21812573_C_A | 709 | G>V | No | 1000Genomes | |
| tmp_3_21812327_G_A | 747 | P>L | No | 1000Genomes | |
| tmp_3_21812279_T_G | 763 | Q>P | No | 1000Genomes | |
| ENSVATH06341090 | 777 | R>H | No | 1000Genomes | |
| ENSVATH12827400 | 837 | K>Q | No | 1000Genomes | |
| ENSVATH06341086 | 840 | H>R | No | 1000Genomes | |
| tmp_3_21811696_C_T | 881 | D>N | No | 1000Genomes | |
| ENSVATH06341085 | 884 | A>T | No | 1000Genomes | |
| tmp_3_21811603_C_T | 887 | A>T | No | 1000Genomes | |
| tmp_3_21811589_C_A | 891 | E>D | No | 1000Genomes | |
| ENSVATH00426939 | 907 | Q>H | No | 1000Genomes | |
| ENSVATH12827398 | 914 | D>N | No | 1000Genomes | |
| tmp_3_21811518_C_T | 915 | G>D | No | 1000Genomes | |
| tmp_3_21811509_T_G | 918 | E>A | No | 1000Genomes | |
| ENSVATH06341082 | 923 | T>I | No | 1000Genomes | |
| tmp_3_21811307_G_T | 949 | D>E | No | 1000Genomes | |
| ENSVATH02523570 | 992 | T>S | No | 1000Genomes | |
| tmp_3_21811076_T_C | 997 | Y>C | No | 1000Genomes | |
| ENSVATH12827364 | 1003 | T>S | No | 1000Genomes | |
| tmp_3_21811008_G_A | 1020 | L>F | No | 1000Genomes | |
| ENSVATH00426936 | 1026 | A>S | No | 1000Genomes | |
| tmp_3_21810981_C_T | 1029 | A>T | No | 1000Genomes |
No associated diseases with F4J738
1 regional properties for F4J738
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Histone H2A/H2B/H3 | 6 - 102 | IPR007125 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| nuclear envelope | The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space). |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| small GTPase binding | Binding to a small monomeric GTPase. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein import into nucleus | The directed movement of a protein from the cytoplasm to the nucleus. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDLPSLALIV | GAAAFSPNPD | ERRAAEQSLN | QLQHTPQHLI | RILQIIVDGG | SDLSVRQSAS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IHFKNFIAKH | WEPHSGDQNI | ILPSDKNVVR | NQILVFVSQV | PPILRVQMGE | CLKTIIYADY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PEQWPELLDW | VKQNLQKPQV | YGALFVLRIL | SSKYEFKSDE | DRAPIHRVVE | ETFPHLLNIF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NNLVHVENPS | LEVADHIKLI | CKIFWSCIYL | ELPRPLFDPN | FFNAWMGLFL | NILERPVPVE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GQPEDPELRK | SWGWWKAKKW | IAHILNRLYT | RFGDLKLQNP | DNKAFAQMFQ | INYAAKILEC |
| 310 | 320 | 330 | 340 | 350 | 360 |
| HLKLLNAIRI | GGYLPDRVIN | LILQYLSNSI | SKSSMYNLLQ | PHLNTLLFEI | VFPLMCFNDN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DQMLWDEDPH | EYVRKGYDII | EDLYSPRTAS | MDFVTELVRK | RGKENFPKFI | QFVVDIFKRY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| NEASLENKPY | RLKDGALLAV | GTLCDKLRQT | EPYKSELENM | LVQHVFPEFS | SPAGHLRAKA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| AWVAGQYANI | DFSDQSNFSK | ALHCVISGMC | DLELPVRVDS | VFALRSFIEA | CKDLDEIRPV |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LPQLLDEFFK | LMKEVENEDL | AFTLETIVYK | FGEEISPYAL | GLCQNLASAF | WRCIDTDNGD |
| 610 | 620 | 630 | 640 | 650 | 660 |
| DETDDAGALA | AVGCLRAIST | ILESISSLPH | LYGQIEPQLL | PIMRKMLTTD | GQDVFEEVLE |
| 670 | 680 | 690 | 700 | 710 | 720 |
| IVSYITTFSP | TISLEMWSLW | PLMMEALVDW | AIDFFPNILV | PLHNYISRGT | GHYLTCKEPD |
| 730 | 740 | 750 | 760 | 770 | 780 |
| YQQNLWNVIS | VLMANKNIDD | SDLEPAPKLL | GIVLQTCKGQ | VDQWVEPYLR | ITLDRLRGAE |
| 790 | 800 | 810 | 820 | 830 | 840 |
| KSSFKCLLVE | VVANAFYYNT | PLALGILQRF | GIATEIFTLW | FQMLQEKKKS | GARSNFKREH |
| 850 | 860 | 870 | 880 | 890 | 900 |
| DKKVCILGLT | SLFSLPAGQL | PGEVLPHVFR | ALLELLVAYK | DQLAEAAKAE | EEEEDEDGDD |
| 910 | 920 | 930 | 940 | 950 | 960 |
| DDMDEFQTDD | EDEDGDDENP | DETDGSTLRK | LAAQAKDFRS | YSDDDDFSDD | DFSDDEELES |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| PIDEVDPFVL | FMDAVTAMQV | SDSPRFQSLT | QTLDPHYHGL | ASTIAQHTEL | RRAEILKEKL |
| EKQSSATVAS |