Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A8MVZ5

Entry ID Method Resolution Chain Position Source
AF-A8MVZ5-F1 Predicted AlphaFoldDB

No variants for A8MVZ5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A8MVZ5

No associated diseases with A8MVZ5

2 regional properties for A8MVZ5

Type Name Position InterPro Accession
domain Immunoglobulin-like domain 24 - 146 IPR007110
domain Immunoglobulin V-set domain 41 - 145 IPR013106

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Single-pass type I membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
external side of plasma membrane The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
signaling receptor binding Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

2 GO annotations of biological process

Name Definition
regulation of cytokine production Any process that modulates the frequency, rate, or extent of production of a cytokine.
T cell receptor signaling pathway The series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O00481 BTN3A1 Butyrophilin subfamily 3 member A1 Homo sapiens (Human) PR
P78410 BTN3A2 Butyrophilin subfamily 3 member A2 Homo sapiens (Human) PR
10 20 30 40 50 60
MAVTCDPEAF LSICFVTLVF LQLPLASIWK ADFDVTGPHA PILAMAGGHV ELQCQLFPNI
70 80 90 100 110 120
SAEDMELRWY RCQPSLAVHM HERGMDMDGE QKWQYRGRTT FMSDHVARGK AMVRSHRVTT
130 140 150 160 170 180
FDNRTYCCRF KDGVKFGEAT VQVQVAGLGR EPRIQVTDQQ DGVRAECTSA GCFPKSWVER
190 200 210 220 230 240
RDFRGQARPA VTNLSASATT RLWAVASSLT LWDRAVEGLS CSISSPLLPE RRKVAESHLP
250 260 270 280 290
ATFSRSSQFT AWKAALPLIL VAMGLVIAGG ICIFWKRQRE KNKASLEEER E