A2VE56

PR
Gene name
PHF20L1
Protein name
PHD finger protein 20-like protein 1
Names
Species
Bos taurus (Bovine)
KEGG Pathway
bta:511990
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

136-316 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A2VE56

Entry ID Method Resolution Chain Position Source
AF-A2VE56-F1 Predicted AlphaFoldDB

45 variants for A2VE56

Variant ID(s) Position Change Description Diseaes Association Provenance
rs798039769 4 K>R No EVA
rs109232177 10 G>A No EVA
rs472242333 37 D>N No EVA
rs452274830 41 G>C No EVA
rs433318731 51 S>R No EVA
rs471059536 57 W>R No EVA
rs437157369 78 L>V No EVA
rs468891519 83 D>Y No EVA
rs475034273 86 D>Y No EVA
rs454913333 89 A>G No EVA
rs466444970 91 E>K No EVA
rs446220718 95 A>V No EVA
rs432532524 96 R>C No EVA
rs470354077 96 R>L No EVA
rs449729023 98 T>A No EVA
rs467249804 99 D>G No EVA
rs478955758 101 R>S No EVA
rs110186647 103 Y>S No EVA
rs482896837 107 I>V No EVA
rs462731739 108 E>* No EVA
rs443782608 109 A>T No EVA
rs475095570 113 E>* No EVA
rs455327434 119 Q>* No EVA
rs455327434 119 Q>K No EVA
rs478550932 147 Q>* No EVA
rs444607394 147 Q>H No EVA
rs458280313 147 Q>L No EVA
rs461813570 152 W>* No EVA
rs441715586 153 C>F No EVA
rs473008630 154 C>G No EVA
rs452862161 159 A>G No EVA
rs439531499 163 N>T No EVA
rs470859988 166 M>I No EVA
rs473515729 170 D>G No EVA
rs453410872 228 E>D No EVA
rs109600341 230 K>N No EVA
rs437908313 289 K>E No EVA
rs469238726 293 V>E No EVA
rs435409286 297 E>G No EVA
rs466777296 300 E>K No EVA
rs447732218 310 E>G No EVA
rs133273200 312 V>A No EVA
rs135812535 313 L>P No EVA
rs137184990 314 H>P No EVA
rs457667055 315 S>R No EVA

No associated diseases with A2VE56

No regional properties for A2VE56

Type Name Position InterPro Accession
No domain, repeats, and functional sites for A2VE56

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Localized to the perinucleolar region
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
NSL complex A histone acetyltransferase complex that catalyzes the acetylation of a histone H4 lysine residues at several positions. In human, it contains the catalytic subunit MOF, NSL1/KIAA1267, NSL2/KANSL2, NSL3/KANSL3, MCRS1, PHF20, OGT1, WDR5 and HCF1.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
histone acetylation The modification of a histone by the addition of an acetyl group.
regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9BVI0 PHF20 PHD finger protein 20 Homo sapiens (Human) PR
Q8BLG0 Phf20 PHD finger protein 20 Mus musculus (Mouse) PR
10 20 30 40 50 60
MSKKPPNRPG ITFEIGARLE ALDYLQKWYP SRIEKIDYEE GKMLVHFERW SHRYDEWIYW
70 80 90 100 110 120
DSNRLRPLER PALRKEGLKD EEDFFDFKAG EEVLARWTDC RYYPAKIEAI NKEGTFTVQF
130 140 150 160 170 180
YDGVIRCLKR MHIKAMPEDA KGQVKAQHPL SWCCPSDPAG SCNQSMGSED WIALVKAAAA
190 200 210 220 230 240
AAAKNKTGNK PRTSANSNKD KEKDERKWFK VPSKKEETST SITTPEVEKK EDLPTSSETF
250 260 270 280 290 300
VGLHVENVPK MVFPQPESTL TNKRKNNQGN SFQAKRARLN KITGLLASKA VGVDGAEKKE
310
DYNETAPMLE QVLHSL