AiPD: Autoinhibited Protein Database

Gene name	ZHD6 (HB24, At2g18350, T30D6.14)
Protein name	Zinc-finger homeodomain protein 6
Names	AtZHD6, Homeobox protein 24, AtHB-24
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT2G18350
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

1-239 (Predicted disordered autoinhibitory region) PR

1-239 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9ZPW7-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
tmp_2_7971905_T_A	2	E>D	No	1000Genomes
ENSVATH05522987	4	R>T	No	1000Genomes
ENSVATH01836345	18	S>P	No	1000Genomes
ENSVATH05522986	22	D>E	No	1000Genomes
tmp_2_7971763_C_T	50	D>N	No	1000Genomes
tmp_2_7971727_T_C	62	I>V	No	1000Genomes
tmp_2_7971601_A_C	104	F>V	No	1000Genomes
tmp_2_7971522_T_G	130	K>T	No	1000Genomes
ENSVATH00236487	139	N>D	No	1000Genomes
tmp_2_7971459_C_T	151	G>E	No	1000Genomes
ENSVATH01836343	155	V>A	No	1000Genomes
ENSVATH01836342	168	C>G	No	1000Genomes
ENSVATH14514782	176	D>N	No	1000Genomes
tmp_2_7971379_T_C	178	N>D	No	1000Genomes
tmp_2_7971378_T_C	178	N>S	No	1000Genomes
ENSVATH14514781	184	F>L	No	1000Genomes
tmp_2_7971346_C_T	189	V>M	No	1000Genomes
tmp_2_7971339_T_G	191	Q>P	No	1000Genomes
tmp_2_7971321_G_A	197	P>L	No	1000Genomes
ENSVATH01836340	211	E>G	No	1000Genomes
ENSVATH14514779	227	L>Q	No	1000Genomes
tmp_2_7971220_C_T	231	E>K	No	1000Genomes
tmp_2_7971197_C_A	238	E>D	No	1000Genomes
ENSVATH01836338	260	K>E	No	1000Genomes
ENSVATH05522983	262	L>S	No	1000Genomes

Type	Name	Position	InterPro Accession
domain	Homeodomain, ZF-HD class	198 - 255	IPR006455
domain	ZF-HD homeobox protein, Cys/His-rich dimerisation domain	80 - 132	IPR006456

		Description
EC Number
Subcellular Localization	Nucleus	Interactions with MIF proteins prevent nuclear subcellular location and leads to a scattered repartition throughout the cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

Name	Definition
DNA binding	Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity	A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
metal ion binding	Binding to a metal ion.
protein homodimerization activity	Binding to an identical protein to form a homodimer.
transcription cis-regulatory region binding	Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.

Name	Definition
regulation of DNA-templated transcription	Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q9FMY7	ZHD13	Zinc-finger homeodomain protein 13	Arabidopsis thaliana (Mouse-ear cress)	PR