Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9FMY7

Entry ID Method Resolution Chain Position Source
AF-Q9FMY7-F1 Predicted AlphaFoldDB

55 variants for Q9FMY7

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_5_17154849_G_C 3 E>D No 1000Genomes
tmp_5_17154860_A_T 7 K>M No 1000Genomes
tmp_5_17154877_A_G 13 K>E No 1000Genomes
tmp_5_17154889_A_C 17 N>H No 1000Genomes
tmp_5_17154893_T_C 18 V>A No 1000Genomes
ENSVATH07307661 18 V>I No 1000Genomes
tmp_5_17154896_A_C 19 K>T No 1000Genomes
tmp_5_17154898_C_G 20 P>A No 1000Genomes
tmp_5_17154902_T_C 21 I>T No 1000Genomes
ENSVATH12399379 23 R>G No 1000Genomes
ENSVATH00697853 25 T>I No 1000Genomes
ENSVATH12399380 25 T>P No 1000Genomes
tmp_5_17154916_G_C 26 G>R No 1000Genomes
tmp_5_17154917_G_T 26 G>V No 1000Genomes
ENSVATH12399382 39 P>S No 1000Genomes
ENSVATH03326514 43 R>S No 1000Genomes
ENSVATH12399383 44 T>P No 1000Genomes
ENSVATH07307664 48 P>L No 1000Genomes
ENSVATH07307664 48 P>Q No 1000Genomes
ENSVATH07307665 49 P>S No 1000Genomes
tmp_5_17154989_C_G,T 50 P>L No 1000Genomes
tmp_5_17154989_C_G,T 50 P>R No 1000Genomes
tmp_5_17154997_G_C 53 D>H No 1000Genomes
ENSVATH00697854 65 Y>F No 1000Genomes
ENSVATH00697855 88 S>G No 1000Genomes
ENSVATH07307669 94 D>N No 1000Genomes
ENSVATH12399398 97 N>K No 1000Genomes
ENSVATH00697856 99 A>V No 1000Genomes
ENSVATH07307670 102 G>C No 1000Genomes
tmp_5_17155150_C_T 104 H>Y No 1000Genomes
ENSVATH07307671 112 L>I No 1000Genomes
tmp_5_17155177_A_C 113 I>L No 1000Genomes
ENSVATH07307672 122 T>K No 1000Genomes
ENSVATH07307673 123 V>I No 1000Genomes
ENSVATH00697857 128 K>R No 1000Genomes
ENSVATH12399400 132 C>Y No 1000Genomes
ENSVATH12399401 145 G>E No 1000Genomes
tmp_5_17155280_G_T 147 S>I No 1000Genomes
tmp_5_17155286_G_A 149 G>E No 1000Genomes
ENSVATH07307675 151 K>T No 1000Genomes
tmp_5_17155297_A_G 153 K>E No 1000Genomes
ENSVATH07307677 158 S>N No 1000Genomes
ENSVATH07307678 161 G>W No 1000Genomes
tmp_5_17155328_C_G 163 P>R No 1000Genomes
ENSVATH07307679 163 P>T No 1000Genomes
ENSVATH14571373
tmp_5_17155347_C_A
169 F>L No 1000Genomes
ENSVATH07307680 170 G>V No 1000Genomes
ENSVATH12399402 175 E>K No 1000Genomes
tmp_5_17155426_G_A 196 D>N No 1000Genomes
ENSVATH12399403 203 W>* No 1000Genomes
tmp_5_17155477_G_A 213 V>I No 1000Genomes
ENSVATH07307681 226 N>T No 1000Genomes
tmp_5_17155549_A_C 237 K>Q No 1000Genomes
tmp_5_17155559_T_C 240 I>T No 1000Genomes
tmp_5_17155563_T_G 241 D>E No 1000Genomes

No associated diseases with Q9FMY7

2 regional properties for Q9FMY7

Type Name Position InterPro Accession
domain Homeodomain, ZF-HD class 180 - 236 IPR006455
domain ZF-HD homeobox protein, Cys/His-rich dimerisation domain 63 - 111 IPR006456

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Interactions with MIF proteins prevent nuclear subcellular location and leads to a scattered repartition throughout the cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

5 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
metal ion binding Binding to a metal ion.
protein homodimerization activity Binding to an identical protein to form a homodimer.
transcription cis-regulatory region binding Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.

1 GO annotations of biological process

Name Definition
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9ZPW7 ZHD6 Zinc-finger homeodomain protein 6 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MDEIKPKKEE NSKRRRNVKP ICRETGDHVH YLPTCKTKPK PTRTHHAPPP ILDSIFKVTH
70 80 90 100 110 120
KPHYYECRKN HAADIGTTAY DGCGEFVSST GEEDSLNCAA CGCHRNFHRE ELIPENGGVT
130 140 150 160 170 180
ETVLEVLKIS SCQFRRIFCS PYGGGKSEGK KKKKEKESYG GDPIIKDRFG GAEEEEGIVK
190 200 210 220 230 240
RLKTKFTAEQ TEKMRDYAEK LRWKVRPERQ EEVEEFCVEI GVNRKNFRIW MNNHKDKIII
DE