Q9YHV3

PR
Gene name
nog3
Protein name
Noggin-3
Names
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
KEGG Pathway
dre:30173
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

14-158 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9YHV3

Entry ID Method Resolution Chain Position Source
AF-Q9YHV3-F1 Predicted AlphaFoldDB

No variants for Q9YHV3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9YHV3

No associated diseases with Q9YHV3

No regional properties for Q9YHV3

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9YHV3

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

9 GO annotations of biological process

Name Definition
cartilage development The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
cloaca development The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates.
determination of left/right symmetry The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.
dorsal/ventral pattern formation The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
embryonic viscerocranium morphogenesis The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.
negative regulation of BMP signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
negative regulation of cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation.
osteoblast differentiation The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.
pronephros development The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9W740 nog2 Noggin-2 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MDNIPYFLAT VLIFSLGFRI EEGMCQHYYL LRPIPSDSLP IVELKEDPDP VLDPKERDLN
70 80 90 100 110 120
ETELRAILGS HFEQNFMSIN PPEDKHAGQD ELNESELMKQ RPNGIMPKEI KAMEFDIQHG
130 140 150 160 170 180
KKHKPSKKLR RRLQLWLWSY TFCPVVHTWQ DLGNRFWPRY LKVGSCYNKR SCSVPEGMVC
190 200 210 220
KPPKSSHLTV LRWRCVQRKG GLKCAWIPVQ YPVISECKCS CPN