AiPD: Autoinhibited Protein Database

Q9Y6E2

Gene name	BZW2 (5MP1)
Protein name	eIF5-mimic protein 1
Names	Basic leucine zipper and W2 domain-containing protein 2
Species	Homo sapiens (Human)
KEGG Pathway	hsa:28969
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-54 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

1-54 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for Q9Y6E2

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9Y6E2-F1	Predicted				AlphaFoldDB

243 variants for Q9Y6E2

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
rs777976475 CA4170437	2	N>S		No	ClinGen ExAC TOPMed gnomAD
CA4170439 rs770948789	4	H>R		No	ClinGen ExAC gnomAD
rs1046378673 CA154063084	13	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA4170443 rs146833365	13	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA366883671 rs1394568442	14	F>L		No	ClinGen gnomAD
CA366883673 rs1315002426	14	F>Y		No	ClinGen gnomAD
CA366883691 rs1340044974	16	T>I		No	ClinGen TOPMed
CA366883694 rs1274145599	17	R>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA366883710 rs1415183083	19	R>S		No	ClinGen gnomAD
TCGA novel	29	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA366883984 rs1233556399	32	D>N		No	ClinGen gnomAD
CA4170479 rs767046038	33	T>I		No	ClinGen ExAC TOPMed gnomAD
rs1274718208 CA366884002	35	V>I		No	ClinGen TOPMed gnomAD
rs1274718208 CA366884003	35	V>L		No	ClinGen TOPMed gnomAD
rs1370584411 CA366884013	36	Q>H		No	ClinGen TOPMed
rs372220513 CA154068444	36	Q>R		No	ClinGen ESP TOPMed
rs772636286 CA4170480	37	G>E		No	ClinGen ExAC gnomAD
rs1298473577 CA366884047	41	A>G		No	ClinGen gnomAD
CA366884046 rs1298473577	41	A>V		No	ClinGen gnomAD
CA366884061 rs1438590936	43	D>E		No	ClinGen gnomAD
CA154068458 VAR_033642 rs35233079	44	D>A		No	ClinGen UniProt Ensembl dbSNP
CA4170483 rs753857266	44	D>N		No	ClinGen ExAC gnomAD
CA4170484 rs754753791	45	L>V		No	ClinGen ExAC gnomAD
CA154068467 rs1033606410	48	V>A		No	ClinGen TOPMed gnomAD
CA4170486 rs751795372	48	V>I		No	ClinGen ExAC gnomAD
rs199513488 CA154068470	49	A>T		No	ClinGen Ensembl
rs781303797 CA4170488	52	L>Q		No	ClinGen ExAC gnomAD
CA4170487 rs539320736	52	L>V		No	ClinGen 1000Genomes ExAC gnomAD
rs1481585007 CA366884120	53	D>V		No	ClinGen gnomAD
CA366884128 rs1461446942	54	S>Y		No	ClinGen TOPMed
TCGA novel	56	G>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1467555813 CA366884155	59	L>V		No	ClinGen gnomAD
TCGA novel	62	R>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1253768868 CA366884179	62	R>S		No	ClinGen TOPMed gnomAD
CA366884215 rs1449809604	67	T>I		No	ClinGen TOPMed
rs139763605 CA4170492	67	T>S		No	ClinGen ESP ExAC gnomAD
rs1196326687 CA366884230	70	D>N		No	ClinGen TOPMed
rs767517929 CA154068494	71	I>V		No	ClinGen TOPMed gnomAD
rs771670267 CA4170496	72	L>M		No	ClinGen ExAC gnomAD
CA4170497 rs772938890	72	L>Q		No	ClinGen ExAC gnomAD
CA4170498 rs760062551	74	A>T		No	ClinGen ExAC gnomAD
rs1429430088 CA366884265	76	S>G		No	ClinGen gnomAD
rs1286562852 CA366884281	78	L>I		No	ClinGen gnomAD
CA4170517 rs371407289	83	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs371407289 CA366884716	83	T>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs1209430562 CA366884724	84	R>C		No	ClinGen gnomAD
rs975997772 CA366884726	84	R>H		No	ClinGen TOPMed gnomAD
rs975997772 CA154071368	84	R>L		No	ClinGen TOPMed gnomAD
CA4170519 rs372301881	85	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA366884761 rs1189840628	87	D>G		No	ClinGen gnomAD
rs1469606802 CA366884787	89	D>E		No	ClinGen gnomAD
rs769904474 CA4170520	89	D>V		No	ClinGen ExAC gnomAD
rs374343456 CA4170521	91	T>A		No	ClinGen ExAC TOPMed gnomAD
CA4170524 rs750594120	92	K>R		No	ClinGen ExAC gnomAD
rs1172407347 CA366884835	93	M>R		No	ClinGen TOPMed gnomAD
CA366884834 rs1172407347	93	M>T		No	ClinGen TOPMed gnomAD
CA366884829 rs1294741504	93	M>V		No	ClinGen TOPMed gnomAD
CA366884860 rs1436149070	95	N>I		No	ClinGen TOPMed gnomAD
CA366884859 rs1436149070	95	N>S		No	ClinGen TOPMed gnomAD
CA4170525 rs760950174	96	H>N		No	ClinGen ExAC TOPMed gnomAD
CA366884918 rs1440738479	100	S>L		No	ClinGen gnomAD
CA366884929 rs1337975897	101	A>G		No	ClinGen gnomAD
CA4170526 rs766412785	102	N>H		No	ClinGen ExAC gnomAD
rs1157402260 CA366884952	103	E>G		No	ClinGen TOPMed
rs753964792 CA4170527	104	D>G		No	ClinGen ExAC TOPMed gnomAD
CA154071387 rs866863564	105	H>Y		No	ClinGen Ensembl
rs755070742 CA4170528	107	T>A		No	ClinGen ExAC gnomAD
rs765620126 CA4170529	107	T>I		No	ClinGen ExAC gnomAD
CA366885000 rs765620126	107	T>S		No	ClinGen ExAC gnomAD
rs144761230 CA4170531	108	I>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA4170532 rs778259070	109	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA4170533 rs565994111	110	N>D		No	ClinGen 1000Genomes ExAC gnomAD
rs1202098440 COSM1622653 CA366885037	111	Y>C	liver [Cosmic]	No	ClinGen cosmic curated gnomAD
CA366885038 rs1202098440	111	Y>F		No	ClinGen gnomAD
CA366885050 rs1583729897	112	A>G		No	ClinGen Ensembl
rs1583729891 CA366885046	112	A>S		No	ClinGen Ensembl
CA4170534 rs536211544	113	Q>E		No	ClinGen 1000Genomes ExAC gnomAD
rs1461429389 CA366885503	114	V>F		No	ClinGen gnomAD
CA4170557 rs759011029	116	N>S		No	ClinGen ExAC gnomAD
rs924061103 CA366885607	122	Y>*		No	ClinGen gnomAD
rs1324937906 CA366885603	122	Y>C		No	ClinGen gnomAD
CA154072067 rs1014153412	124	Y>C		No	ClinGen TOPMed
CA366885638 rs1562489369	126	E>Q		No	ClinGen Ensembl
CA154072077 rs369984633	127	K>N		No	ClinGen ESP ExAC TOPMed gnomAD
rs200567141 CA4170559 COSM485154	127	K>R	kidney [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
rs1271212523 CA366885656	128	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
TCGA novel	129	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA4170561 rs780955589	130	E>A		No	ClinGen ExAC gnomAD
rs1260399912 CA366885701	134	K>R		No	ClinGen gnomAD
CA366885857 rs1433062799	136	L>F		No	ClinGen gnomAD
rs1377038665 CA366885863	137	L>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
TCGA novel	140	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA366885899 rs1583736584	141	K>*		No	ClinGen Ensembl
CA366885915 rs1306205736	142	A>G		No	ClinGen gnomAD
CA366885939 rs1583736593	144	S>F		No	ClinGen Ensembl
rs748090719 CA4170606	145	E>K		No	ClinGen ExAC TOPMed gnomAD
rs1346753253 CA366885995	149	T>K		No	ClinGen TOPMed gnomAD
CA366886029 rs1292741642	152	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA366886059 rs1255204746	155	S>A		No	ClinGen TOPMed
rs771841398 CA4170607	155	S>L		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	156	G>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1583736669 CA366886111	159	L>R		No	ClinGen Ensembl
CA154073416 rs1056079577	161	N>S		No	ClinGen TOPMed gnomAD
CA4170610 rs148948416	162	G>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA4170611 rs374366357	163	T>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA154073422 rs980360074	163	T>P		No	ClinGen Ensembl
CA366886176 rs762472281	166	A>S		No	ClinGen ExAC gnomAD
CA4170615 rs762472281	166	A>T		No	ClinGen ExAC gnomAD
CA366886182 rs1583736737	167	T>P		No	ClinGen Ensembl
rs750863375 CA4170617	168	I>N		No	ClinGen ExAC TOPMed gnomAD
rs750863375 CA366886199	168	I>T		No	ClinGen ExAC TOPMed gnomAD
rs1297341046 CA366886193	168	I>V		No	ClinGen gnomAD
CA366886220 rs1331496651	170	T>A		No	ClinGen gnomAD
CA4170618 rs774065384	172	L>*		No	ClinGen ExAC
rs1441207164 CA366886244	172	L>V		No	ClinGen TOPMed
CA366886282 rs1305195566	175	D>N		No	ClinGen gnomAD
rs369538600 CA366886300	176	S>N		No	ClinGen ESP ExAC TOPMed gnomAD
rs369538600 CA4170621	176	S>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs199770355 CA4170622	178	V>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1481937235 CA366886336	179	K>R		No	ClinGen gnomAD
CA4170656 rs771321407	182	I>S		No	ClinGen ExAC gnomAD
CA4170657 rs572468645	183	A>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA366886718 rs572468645	183	A>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs145957585 CA4170659	184	A>T		No	ClinGen ESP ExAC gnomAD
CA4170660 rs775156427	184	A>V		No	ClinGen ExAC gnomAD
CA154074933 rs1032523070	193	A>T		No	ClinGen Ensembl
CA836140745 rs1270612460	194	W>*		No	ClinGen Ensembl
CA366886821 rs1373165517	195	M>I		No	ClinGen gnomAD
rs1222172004 CA366886824	196	A>T		No	ClinGen gnomAD
CA366886888 rs1225135493	201	N>Y		No	ClinGen TOPMed
rs767317583 CA4170665	203	V>A		No	ClinGen ExAC gnomAD
CA154074940 rs988421846	203	V>F		No	ClinGen Ensembl
rs1360647335 CA366886934	204	T>I		No	ClinGen TOPMed
CA366886931 rs1360647335	204	T>N		No	ClinGen TOPMed
CA4170666 rs375628464	205	S>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs1175011928 CA366887007	210	A>T		No	ClinGen gnomAD
rs748392463 CA4170669	211	N>S		No	ClinGen ExAC gnomAD
rs528975449 CA154074945	212	L>V		No	ClinGen 1000Genomes gnomAD
CA366887074 rs1172621167	214	K>*		No	ClinGen gnomAD
CA4170672 rs760256408	214	K>N		No	ClinGen ExAC gnomAD
rs141321905 CA4170673	217	L>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA4170690 rs751535805	225	Q>H		No	ClinGen ExAC gnomAD
CA366888190 rs1420043520	226	S>N		No	ClinGen TOPMed
rs953144274 CA154076334	226	S>R		No	ClinGen Ensembl
CA4170691 rs757362212	227	V>M		No	ClinGen ExAC TOPMed gnomAD
CA154076339 rs985569614	228	D>A		No	ClinGen Ensembl
rs911413334 CA154076343	233	Y>*		No	ClinGen Ensembl
TCGA novel	235	T>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1392951943 CA366888257	235	T>S		No	ClinGen gnomAD
CA366888266 rs746394268	237	A>P		No	ClinGen ExAC gnomAD
CA4170693 rs746394268	237	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA4170694 rs558675877	241	E>G		No	ClinGen ExAC gnomAD
CA366888315 rs765564580	244	D>E		No	ClinGen ExAC TOPMed gnomAD
CA4170696 rs141647020	244	D>N		No	ClinGen ESP ExAC TOPMed gnomAD
rs774060534 CA4170698	246	L>F		No	ClinGen ExAC gnomAD
CA366888332 rs1357855982	247	R>Q		No	ClinGen gnomAD
TCGA novel	249	Q>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs771637961 CA4170701	258	L>V		No	ClinGen ExAC TOPMed gnomAD
rs760736472 CA4170702	263	Q>H		No	ClinGen ExAC TOPMed gnomAD
CA366888454 rs1291250809	265	R>C		No	ClinGen TOPMed
CA366888455 rs1356337797	265	R>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs759389326 CA4170705	268	Q>H		No	ClinGen ExAC gnomAD
CA4170704 rs751222719	268	Q>R		No	ClinGen ExAC TOPMed gnomAD
rs1370634430 CA366888477	269	E>Q		No	ClinGen TOPMed gnomAD
CA154076380 rs964599232	270	C>R		No	ClinGen TOPMed
rs764155066 CA4170706	271	P>R		No	ClinGen ExAC TOPMed gnomAD
rs757233860 CA4170708	272	I>M		No	ClinGen ExAC gnomAD
rs1421720292 CA366888513	274	E>A		No	ClinGen gnomAD
CA4170724 rs759210353	276	V>A		No	ClinGen ExAC gnomAD
rs776714807 CA4170723	276	V>M		No	ClinGen ExAC
CA4170725 rs765101857	278	Y>C		No	ClinGen ExAC TOPMed gnomAD
CA366888705 rs765101857	278	Y>F		No	ClinGen ExAC TOPMed gnomAD
CA4170727 rs762131738	279	V>I		No	ClinGen ExAC gnomAD
TCGA novel	285	R>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA366888775 rs1396517479	287	D>E		No	ClinGen gnomAD
rs750555836 CA4170729	288	L>I		No	ClinGen ExAC TOPMed gnomAD
CA366888782 rs1486461697	289	P>T		No	ClinGen gnomAD
rs1241596634 CA366888793	290	E>V		No	ClinGen gnomAD
CA4170731 rs766834462	292	A>V		No	ClinGen ExAC gnomAD
TCGA novel	293	V>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA366888843 rs1258102588	298	W>*		No	ClinGen gnomAD
CA4170733 rs755277642	300	C>G		No	ClinGen ExAC TOPMed gnomAD
rs755277642 CA366888853	300	C>R		No	ClinGen ExAC TOPMed gnomAD
rs779376411 CA4170734	301	I>V		No	ClinGen ExAC TOPMed gnomAD
rs758127553 CA4170736	304	A>T		No	ClinGen ExAC gnomAD
CA4170737 rs777582035	305	V>I		No	ClinGen ExAC gnomAD
rs1173758539 CA366888946	312	E>V		No	ClinGen gnomAD
rs769442399 CA4170742	320	K>N		No	ClinGen ExAC gnomAD
CA366889004 rs1583751682	321	H>P		No	ClinGen Ensembl
rs915427730 CA154077205	323	K>R		No	ClinGen Ensembl
CA366889036 rs1228685667	324	Q>R		No	ClinGen TOPMed gnomAD
CA366889046 rs1215677294	325	Y>*		No	ClinGen gnomAD
CA366889048 rs1461127627	326	A>S		No	ClinGen TOPMed
rs1260736239 CA366889053	326	A>V		No	ClinGen gnomAD
rs375769865 CA154077709	331	V>M		No	ClinGen ESP TOPMed gnomAD
CA366889094 rs1221573337	333	S>I		No	ClinGen TOPMed
rs753174373 CA4170775	334	S>C		No	ClinGen ExAC gnomAD
CA366889100 rs753174373	334	S>F		No	ClinGen ExAC gnomAD
rs764599893 COSM1088074 CA4170777	335	Q>R	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
CA4170779 rs757033515	337	Q>H		No	ClinGen ExAC gnomAD
rs751223933 CA4170778	337	Q>K		No	ClinGen ExAC gnomAD
CA366889157 rs1302785740	340	L>V		No	ClinGen gnomAD
rs780551598 CA4170781	341	I>S		No	ClinGen ExAC gnomAD
CA4170780 rs780551598	341	I>T		No	ClinGen ExAC gnomAD
TCGA novel	344	Q>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	345	K>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs755580498 CA4170782	345	K>R		No	ClinGen ExAC gnomAD
rs146163758 CA4170783	347	Q>K		No	ClinGen ESP ExAC gnomAD
CA366889491 rs1243640147	349	Y>C		No	ClinGen TOPMed
CA366889540 rs1349473469	352	D>E		No	ClinGen gnomAD
CA366889568 rs1236869110	355	H>R		No	ClinGen gnomAD
rs747219700 CA4170787	355	H>Y		No	ClinGen ExAC gnomAD
rs759622263 CA4170790	361	Q>R		No	ClinGen ExAC gnomAD
rs1156458478 CA366889643	365	V>A		No	ClinGen gnomAD
rs769784877 CA4170791	365	V>I		No	ClinGen ExAC TOPMed gnomAD
rs1316217728 COSM88508 CA366889646	366	L>V	ovary [Cosmic]	No	ClinGen cosmic curated TOPMed
rs776042480 CA4170792	367	F>L		No	ClinGen ExAC gnomAD
TCGA novel	367	F>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1453744062 CA366890500	372	V>I		No	ClinGen gnomAD
CA366890519 rs1274101695	373	L>P		No	ClinGen gnomAD
CA4170812 rs769226107	375	E>K		No	ClinGen ExAC gnomAD
rs560509631 CA366890569	377	A>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs560509631 CA4170813	377	A>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA366890583 rs1196249517	379	L>M		No	ClinGen gnomAD
rs762224963 CA4170814	382	Y>C		No	ClinGen ExAC gnomAD
CA4170818 rs760313917	396	D>A		No	ClinGen ExAC gnomAD
rs1325260363 CA366890748	397	Q>P		No	ClinGen TOPMed
CA4170820 COSM1488446 rs753289484	398	M>I	Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs765901920 CA4170819	398	M>T		No	ClinGen ExAC TOPMed gnomAD
rs1192097564 CA366890756	398	M>V		No	ClinGen gnomAD
TCGA novel	401	F>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA366890826 rs1401114132	402	V>F		No	ClinGen gnomAD
rs1392095546 CA366890843	403	E>D		No	ClinGen TOPMed
rs1431611010 CA366890838	403	E>V		No	ClinGen TOPMed
rs1321839687 CA366890885	406	Q>P		No	ClinGen gnomAD
TCGA novel	412	S>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA366891067 rs1257281634	412	S>P		No	ClinGen TOPMed
rs755081715 COSM170916 CA4170847	413	E>K	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
CA366891082 rs148788756	414	S>*		No	ClinGen ESP ExAC TOPMed gnomAD
CA4170848 rs148788756	414	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs1358071160 CA366891098	417	E>K		No	ClinGen TOPMed
rs778349274 CA366891120	419	N>K		No	ClinGen ExAC gnomAD
rs1219180228 CA366891118	419	N>S		No	ClinGen gnomAD

No associated diseases with Q9Y6E2

2 regional properties for Q9Y6E2

Type	Name	Position	InterPro Accession
domain	W2 domain	248 - 415	IPR003307
domain	BZW1/2, W2 domain	218 - 408	IPR043510

Functions

		Description
EC Number
Subcellular Localization	Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

2 GO annotations of cellular component

Name	Definition
cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
membrane	A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

1 GO annotations of molecular function

Name	Definition
cadherin binding	Binding to cadherin, a type I membrane protein involved in cell adhesion.

1 GO annotations of biological process

Name	Definition
regulation of translational initiation	Any process that modulates the frequency, rate or extent of translational initiation.

3 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q9VNE2	kra	Protein krasavietz	Drosophila melanogaster (Fruit fly)	PR
Q91VK1	Bzw2	eIF5-mimic protein 1	Mus musculus (Mouse)	PR
Q803N9	bzw1b	eIF5-mimic protein 2-B	Danio rerio (Zebrafish) (Brachydanio rerio)	PR

10	20	30	40	50	60
MNKHQKPVLT	GQRFKTRKRD	EKEKFEPTVF	RDTLVQGLNE	AGDDLEAVAK	FLDSTGSRLD
70	80	90	100	110	120
YRRYADTLFD	ILVAGSMLAP	GGTRIDDGDK	TKMTNHCVFS	ANEDHETIRN	YAQVFNKLIR
130	140	150	160	170	180
RYKYLEKAFE	DEMKKLLLFL	KAFSETEQTK	LAMLSGILLG	NGTLPATILT	SLFTDSLVKE
190	200	210	220	230	240
GIAASFAVKL	FKAWMAEKDA	NSVTSSLRKA	NLDKRLLELF	PVNRQSVDHF	AKYFTDAGLK
250	260	270	280	290	300
ELSDFLRVQQ	SLGTRKELQK	ELQERLSQEC	PIKEVVLYVK	EEMKRNDLPE	TAVIGLLWTC
310	320	330	340	350	360
IMNAVEWNKK	EELVAEQALK	HLKQYAPLLA	VFSSQGQSEL	ILLQKVQEYC	YDNIHFMKAF
370	380	390	400	410
QKIVVLFYKA	DVLSEEAILK	WYKEAHVAKG	KSVFLDQMKK	FVEWLQNAEE	ESESEGEEN