Q91VK1

PR
Gene name
Bzw2 (5mp1)
Protein name
eIF5-mimic protein 1
Names
Basic leucine zipper and W2 domain-containing protein 2
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:66912
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-53 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q91VK1

Entry ID Method Resolution Chain Position Source
AF-Q91VK1-F1 Predicted AlphaFoldDB

22 variants for Q91VK1

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3389250176 9 L>I No EVA
rs3389222593 15 K>E No EVA
rs3389239744 49 A>S No EVA
rs3402770016 78 L>H No EVA
rs3389236082 111 Y>H No EVA
rs3389236054 115 F>I No EVA
rs3389211702 123 K>N No EVA
rs3389239760 128 A>V No EVA
rs3389236442 143 F>C No EVA
rs3389205596 155 S>T No EVA
rs3389222594 164 L>I No EVA
rs3389222614 176 S>G No EVA
rs3389250098 219 L>V No EVA
rs13467053 231 A>S No EVA
rs13467053 231 A>T No EVA
rs3389244606 272 I>F No EVA
rs3402770018 323 K>* No EVA
rs3389250144 331 V>M No EVA
rs13467052 343 L>M No EVA
rs3389236025 347 Q>K No EVA
rs3389205576 353 N>S No EVA
rs3389222650 390 G>S No EVA

No associated diseases with Q91VK1

2 regional properties for Q91VK1

Type Name Position InterPro Accession
domain W2 domain 248 - 415 IPR003307
domain BZW1/2, W2 domain 218 - 408 IPR043510

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
regulation of translational initiation Any process that modulates the frequency, rate or extent of translational initiation.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9VNE2 kra Protein krasavietz Drosophila melanogaster (Fruit fly) PR
Q9Y6E2 BZW2 eIF5-mimic protein 1 Homo sapiens (Human) PR
Q803N9 bzw1b eIF5-mimic protein 2-B Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MNKHQKPVLT GQRFKTRKRD EKEKFEPTVF RDTLVQGLNE AGDDLEAVAK FLDSTGSRLD
70 80 90 100 110 120
YRRYADTLFD ILVAGSMLAP GGTRIDDGDK TKMTNHCVFS ANEDHETIRN YAQVFNKLIR
130 140 150 160 170 180
RYKYLEKAFE DEMKKLLLFL KAFSEAEQTK LAMLSGILLG NGTLPATILT SLFTDSLVKE
190 200 210 220 230 240
GIAASFAVKL FKAWMAEKDA NSVTSSLRKA NLDKRLLELF PVNRQSVDHF AKYFTDAGLK
250 260 270 280 290 300
ELSDFLRVQQ SLGTRKELQK ELQERLSQEC PIKEVVLYVK EEMKRNDLPE TAVIGLLWTC
310 320 330 340 350 360
IMNAVEWNKK EELVAEQALK HLKQYAPLLA VFSSQGQSEL VLLQKVQEYC YDNIHFMKAF
370 380 390 400 410
QKIVVLFYKA DVLSEEAILK WYKEAHAAKG KSVFLDQMKK FVEWLQNAEE ESESEGEES