Q9Y5Z7
PR
Gene name |
HCFC2 |
Protein name |
Host cell factor 2 |
Names |
HCF-2, C2 factor |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:29915 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9Y5Z7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9Y5Z7-F1 | Predicted | AlphaFoldDB |
390 variants for Q9Y5Z7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs1318119328 CA386333661 |
2 | A>V | No |
ClinGen gnomAD |
|
|
rs1363441085 CA386333681 |
3 | A>V | No |
ClinGen gnomAD |
|
|
rs904342667 CA242587120 |
4 | P>L | No |
ClinGen TOPMed |
|
|
CA386333688 rs1230958166 |
4 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
CA386333713 rs1298597226 |
5 | S>G | No |
ClinGen gnomAD |
|
|
rs370124268 CA242587135 CA386333734 |
5 | S>R | No |
ClinGen ESP TOPMed gnomAD |
|
|
rs750318884 CA6754841 |
7 | L>V | No |
ClinGen ExAC gnomAD |
|
|
CA386333794 rs1273761483 |
8 | N>H | No |
ClinGen gnomAD |
|
|
rs1566221187 CA386333902 |
11 | R>Q | No |
ClinGen Ensembl |
|
|
CA386333949 rs1271060278 |
13 | S>F | No |
ClinGen TOPMed |
|
|
CA6754843 rs781068820 |
15 | F>L | No |
ClinGen ExAC gnomAD |
|
|
CA386334010 rs1262186615 |
16 | T>M | No |
ClinGen TOPMed |
|
|
CA6754845 rs770095641 |
16 | T>P | No |
ClinGen ExAC gnomAD |
|
|
CA242587210 rs182417219 |
22 | A>P | No |
ClinGen 1000Genomes gnomAD |
|
|
rs182417219 CA386334102 |
22 | A>S | No |
ClinGen 1000Genomes gnomAD |
|
|
rs1385278764 CA386334510 CA386334506 |
35 | M>I | No |
ClinGen TOPMed gnomAD |
|
|
rs763785064 CA6754854 |
41 | G>R | No |
ClinGen ExAC gnomAD |
|
|
CA242587302 rs2700500 VAR_050044 |
46 | A>S | No |
ClinGen UniProt Ensembl dbSNP |
|
|
CA386334852 rs1447434456 |
52 | Y>C | No |
ClinGen TOPMed |
|
|
CA6754855 rs534161236 |
53 | N>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA6754856 rs761659441 |
54 | T>M | No |
ClinGen ExAC gnomAD |
|
|
CA386334889 rs1268481623 |
54 | T>S | No |
ClinGen gnomAD |
|
| TCGA novel | 55 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA6754884 rs756321771 |
56 | T>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM1358319 rs756321771 CA6754883 |
56 | T>M | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA386335081 rs1280061336 |
57 | N>H | No |
ClinGen gnomAD |
|
|
CA6754886 rs757380116 |
60 | F>L | No |
ClinGen ExAC gnomAD |
|
|
CA386335268 rs1314546069 |
64 | V>I | No |
ClinGen gnomAD |
|
|
CA6754888 rs746266215 |
65 | R>T | No |
ClinGen ExAC gnomAD |
|
|
CA6754890 rs780601426 |
66 | G>R | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 67 | D>missing | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1355746312 CA386335393 |
69 | P>A | No |
ClinGen TOPMed |
|
|
rs1237425648 CA386335471 |
73 | A>T | No |
ClinGen gnomAD |
|
|
CA242588847 rs376389345 |
80 | D>N | No |
ClinGen ESP |
|
|
CA386335668 rs1183996443 |
82 | T>S | No |
ClinGen gnomAD |
|
| TCGA novel | 83 | R>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA6754894 rs747860413 |
84 | I>V | No |
ClinGen ExAC |
|
|
rs769384943 CA6754895 |
85 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1449144616 CA386335760 |
87 | F>L | No |
ClinGen gnomAD |
|
| TCGA novel | 90 | M>W | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 96 | Y>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 98 | N>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs917566185 CA242588964 |
98 | N>K | No |
ClinGen TOPMed |
|
|
CA6754898 rs766264313 |
99 | E>* | No |
ClinGen ExAC gnomAD |
|
|
rs759481011 CA6754900 |
101 | Y>H | No |
ClinGen ExAC gnomAD |
|
|
CA6754920 COSM430195 rs774250277 |
107 | R>H | Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs1366956772 CA386337131 |
114 | K>E | No |
ClinGen gnomAD |
|
|
rs1430971615 CA386337145 COSM1739888 |
115 | P>T | NS [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
rs759566755 CA386337159 |
116 | H>D | No |
ClinGen ExAC gnomAD |
|
|
rs759566755 CA6754921 |
116 | H>Y | No |
ClinGen ExAC gnomAD |
|
|
CA242590435 rs866483722 |
117 | P>L | No |
ClinGen Ensembl |
|
|
CA6754922 rs772184239 |
118 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA242590446 rs1008487928 |
118 | P>S | No |
ClinGen Ensembl |
|
|
CA6754923 rs150909028 |
119 | P>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA6754924 rs761864841 |
121 | G>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs765341316 CA6754925 |
123 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1270370053 CA386337322 |
127 | R>G | No |
ClinGen gnomAD |
|
|
rs1305607617 CA386337407 |
132 | F>L | No |
ClinGen gnomAD |
|
|
rs1443735795 CA386337421 |
133 | S>P | No |
ClinGen TOPMed |
|
|
rs1416929619 CA386337486 |
135 | Y>* | No |
ClinGen TOPMed |
|
|
rs755307706 CA6754930 |
135 | Y>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA6754929 rs534442693 |
135 | Y>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1191785404 CA386337504 |
137 | N>D | No |
ClinGen TOPMed gnomAD |
|
|
rs1566223480 CA386337514 |
137 | N>K | No |
ClinGen Ensembl |
|
|
rs557800723 CA6754931 |
137 | N>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
| TCGA novel | 138 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1156737438 CA386337702 |
148 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
COSM174273 CA6754933 rs755592892 |
150 | E>K | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs755592892 CA386337742 |
150 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1322465683 CA386337777 |
151 | D>E | No |
ClinGen gnomAD |
|
|
rs777271824 CA6754934 |
154 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1283314478 CA386337841 |
157 | P>R | No |
ClinGen gnomAD |
|
| TCGA novel | 160 | L>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA6754952 rs202081777 |
170 | H>D | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs753445157 CA6754953 |
170 | H>R | No |
ClinGen ExAC gnomAD |
|
|
CA386338967 rs202081777 |
170 | H>Y | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1358793784 CA386338984 |
171 | G>A | No |
ClinGen gnomAD |
|
|
rs756794025 CA6754954 |
173 | G>D | No |
ClinGen ExAC gnomAD |
|
|
rs1274088881 CA386339015 |
174 | V>I | No |
ClinGen gnomAD |
|
|
rs113829238 CA6754955 |
179 | I>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1209602035 CA386339129 |
182 | T>N | No |
ClinGen TOPMed |
|
|
CA6754956 rs745498802 |
185 | V>A | No |
ClinGen ExAC gnomAD |
|
|
CA6754957 rs758281586 |
188 | S>F | No |
ClinGen ExAC gnomAD |
|
|
rs1186615399 CA386339347 |
197 | I>T | No |
ClinGen gnomAD |
|
|
rs1265143908 CA386339362 |
198 | Y>C | No |
ClinGen gnomAD |
|
|
rs768259042 CA242598921 |
200 | K>R | No |
ClinGen TOPMed |
|
| TCGA novel | 202 | D>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1438442231 CA386339471 |
204 | G>A | No |
ClinGen TOPMed |
|
|
CA386339484 rs1446131798 |
205 | S>I | No |
ClinGen gnomAD |
|
|
rs1446131798 CA386339486 |
205 | S>N | No |
ClinGen gnomAD |
|
|
rs1163810710 CA386339507 |
207 | K>E | No |
ClinGen gnomAD |
|
|
rs1389101801 CA386339523 |
208 | M>V | No |
ClinGen gnomAD |
|
|
rs1320744813 CA386339545 |
209 | Y>H | No |
ClinGen TOPMed |
|
| TCGA novel | 223 | W>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs749438311 CA6754962 |
224 | Q>K | No |
ClinGen ExAC gnomAD |
|
|
rs12422501 CA242598952 |
228 | E>K | No |
ClinGen Ensembl |
|
|
CA242599840 rs994659311 |
236 | E>* | No |
ClinGen Ensembl |
|
|
CA6754974 rs758027389 |
236 | E>G | No |
ClinGen ExAC gnomAD |
|
|
CA242599846 rs757149889 |
237 | T>A | No |
ClinGen gnomAD |
|
| TCGA novel | 248 | H>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1363320149 CA386341117 |
252 | V>F | No |
ClinGen gnomAD |
|
| TCGA novel | 255 | N>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 262 | G>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 262 | G>W | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1303451234 CA386341354 |
263 | W>R | No |
ClinGen gnomAD |
|
|
CA6754996 rs749902760 |
264 | V>I | No |
ClinGen ExAC gnomAD |
|
|
CA6754998 rs766125324 |
266 | H>R | No |
ClinGen ExAC gnomAD |
|
|
CA6754999 VAR_033984 rs17035206 |
268 | G>A | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs754817344 CA6755000 |
269 | E>G | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 269 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA386341476 rs1207579841 |
273 | T>S | No |
ClinGen gnomAD |
|
|
CA242600932 rs983394368 |
275 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
CA242600928 rs1019821347 |
275 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1180322338 CA386341636 |
286 | F>S | No |
ClinGen TOPMed |
|
|
rs1341624284 CA386341751 |
293 | T>K | No |
ClinGen gnomAD |
|
|
rs1461350000 CA386341758 |
294 | T>A | No |
ClinGen Ensembl |
|
|
rs762583470 CA6755014 |
294 | T>I | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 296 | W>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs759074795 CA6755017 |
302 | D>H | No |
ClinGen ExAC gnomAD |
|
|
rs1457318682 CA386341878 |
304 | Q>R | No |
ClinGen TOPMed |
|
|
rs1345768728 CA386341898 |
305 | E>D | No |
ClinGen TOPMed |
|
|
rs1437663441 CA386341907 |
306 | D>V | No |
ClinGen TOPMed |
|
|
rs1160219217 CA386341904 |
306 | D>Y | No |
ClinGen TOPMed |
|
| TCGA novel | 308 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| rs776023139 | 309 | N>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1444252024 CA386342004 |
309 | N>K | No |
ClinGen gnomAD |
|
|
rs767326665 CA6755019 |
311 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA242601098 rs752539782 |
314 | P>A | No |
ClinGen ExAC gnomAD |
|
|
CA6755020 rs752539782 |
314 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA386342185 rs1316721415 |
319 | C>Y | No |
ClinGen gnomAD |
|
|
rs755874030 CA6755022 |
322 | A>E | No |
ClinGen ExAC gnomAD |
|
|
CA386342236 rs1359635263 |
322 | A>P | No |
ClinGen gnomAD |
|
|
CA6755021 rs755874030 |
322 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA6755025 rs371559185 |
323 | I>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA6755024 rs371559185 |
323 | I>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA386342284 rs1482486099 |
324 | G>D | No |
ClinGen gnomAD |
|
|
rs144090047 CA6755027 |
324 | G>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs981595047 CA242601172 |
326 | R>* | No |
ClinGen Ensembl |
|
| TCGA novel | 328 | Y>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 330 | W>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs867509700 CA242601181 |
332 | G>R | No |
ClinGen Ensembl |
|
|
CA386342624 rs1185752368 |
337 | K>Q | No |
ClinGen gnomAD |
|
| TCGA novel | 339 | A>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA386342650 rs1244003271 |
339 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
CA242601189 rs982156482 |
340 | L>P | No |
ClinGen TOPMed gnomAD |
|
|
rs1261896158 CA386342793 |
345 | C>F | No |
ClinGen TOPMed |
|
| TCGA novel | 345 | C>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1411644468 CA386342908 |
351 | Y>C | No |
ClinGen gnomAD |
|
|
CA386342909 rs1411644468 |
351 | Y>F | No |
ClinGen gnomAD |
|
|
CA386342956 rs1171053508 |
354 | T>I | No |
ClinGen gnomAD |
|
|
CA6755042 rs767200264 |
358 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA6755044 rs201165064 |
359 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
rs763815802 CA6755045 |
360 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1366607621 CA386343231 |
361 | S>C | No |
ClinGen TOPMed |
|
|
CA242604027 rs879081926 |
362 | Q>E | No |
ClinGen Ensembl |
|
|
rs753815419 CA6755046 |
363 | V>L | No |
ClinGen ExAC |
|
|
rs1430856779 CA386343297 |
371 | N>K | No |
ClinGen gnomAD |
|
|
CA386343296 rs1438379295 |
371 | N>S | No |
ClinGen TOPMed |
|
|
CA6755048 rs766502251 |
372 | S>C | No |
ClinGen ExAC gnomAD |
|
|
rs766502251 CA386343303 |
372 | S>F | No |
ClinGen ExAC gnomAD |
|
|
rs367627562 CA242604047 |
378 | D>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ESP NCI-TCGA |
|
rs1185845 CA242604064 |
379 | E>K | No |
ClinGen Ensembl |
|
|
CA242604073 rs1050565135 |
380 | V>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1050565135 CA386343389 |
380 | V>M | No |
ClinGen TOPMed gnomAD |
|
|
CA6755050 rs755077426 |
381 | S>T | No |
ClinGen ExAC gnomAD |
|
|
CA6755051 rs781627273 |
382 | T>A | No |
ClinGen ExAC gnomAD |
|
|
CA6755053 rs756553133 |
383 | V>A | No |
ClinGen ExAC gnomAD |
|
|
CA242604107 rs866514947 |
383 | V>I | No |
ClinGen Ensembl |
|
|
rs777961588 CA6755054 |
385 | G>V | No |
ClinGen ExAC |
|
| TCGA novel | 386 | Y>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs866256014 CA242604123 |
387 | L>F | No |
ClinGen Ensembl |
|
| TCGA novel | 388 | L>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1266837635 CA386343567 |
391 | S>N | No |
ClinGen gnomAD |
|
|
rs771394333 CA6755056 |
392 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA386343652 rs1472151778 |
398 | A>P | No |
ClinGen gnomAD |
|
|
CA386343678 rs1409755178 |
400 | S>T | No |
ClinGen gnomAD |
|
|
rs1363149779 CA386343708 |
402 | D>E | No |
ClinGen TOPMed gnomAD |
|
|
CA386343697 rs1322356936 |
402 | D>H | No |
ClinGen gnomAD |
|
|
CA6755058 rs774893288 |
405 | A>P | No |
ClinGen ExAC gnomAD |
|
|
rs771555154 CA6755060 |
409 | M>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA6755059 rs368216155 |
409 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1163611912 CA386344430 |
412 | V>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1370517732 CA386344435 |
413 | R>G | No |
ClinGen TOPMed gnomAD |
|
|
rs1336720823 CA386344458 |
415 | D>E | No |
ClinGen gnomAD |
|
|
rs1331365871 CA386344456 |
415 | D>G | No |
ClinGen gnomAD |
|
|
CA386344460 rs1233165834 |
416 | P>A | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 416 | P>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA386344481 rs1447676090 |
419 | Q>E | No |
ClinGen gnomAD |
|
|
rs1313206520 CA386344490 |
420 | G>S | No |
ClinGen gnomAD |
|
|
CA242605037 rs1020845522 |
420 | G>V | No |
ClinGen gnomAD |
|
|
CA6755067 rs373952165 |
421 | S>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA6755068 rs151222227 |
421 | S>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA6755069 rs542271303 |
422 | N>K | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA6755070 rs140444104 |
425 | V>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA386344528 rs1274931299 |
426 | P>S | No |
ClinGen gnomAD |
|
|
rs375736197 CA6755076 |
429 | I>V | No |
ClinGen ESP ExAC gnomAD |
|
|
CA242559318 rs978795089 |
430 | N>S | No |
ClinGen gnomAD |
|
|
CA386340312 rs1298731862 |
432 | T>P | No |
ClinGen TOPMed |
|
|
rs184476139 CA6755077 |
433 | I>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA242559321 rs925639586 |
433 | I>V | No |
ClinGen Ensembl |
|
|
CA242559325 rs988501366 |
434 | N>H | No |
ClinGen Ensembl |
|
|
CA6755078 rs202212280 |
435 | S>N | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1593608707 CA386340353 |
436 | T>K | No |
ClinGen Ensembl |
|
|
CA6755079 rs746682588 |
438 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs1593608723 CA386340383 |
439 | E>K | No |
ClinGen Ensembl |
|
|
CA6755080 rs768240762 |
440 | Q>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA242559345 rs1049672998 |
441 | P>S | No |
ClinGen Ensembl |
|
|
rs1593608745 CA386340425 |
442 | A>G | No |
ClinGen Ensembl |
|
|
rs761578497 CA6755082 |
442 | A>T | No |
ClinGen ExAC gnomAD |
|
|
rs769617449 CA6755083 |
443 | T>A | No |
ClinGen ExAC gnomAD |
|
|
CA386340452 rs1374180202 |
445 | E>Q | No |
ClinGen gnomAD |
|
|
CA242559352 rs147689138 |
446 | T>I | No |
ClinGen ESP ExAC gnomAD |
|
|
CA6755084 rs147689138 |
446 | T>S | No |
ClinGen ESP ExAC gnomAD |
|
|
rs866585573 CA242559354 |
447 | S>L | No |
ClinGen TOPMed |
|
|
CA6755085 rs762946398 |
448 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1470462185 CA386340521 |
450 | N>S | No |
ClinGen gnomAD |
|
|
CA386340535 rs1479784846 |
451 | K>I | No |
ClinGen TOPMed |
|
|
rs767727994 CA6755086 |
451 | K>Q | No |
ClinGen ExAC gnomAD |
|
|
rs1382989999 CA386340586 |
455 | K>T | No |
ClinGen gnomAD |
|
|
CA386340607 rs1319017882 |
457 | L>Q | No |
ClinGen gnomAD |
|
|
CA6755088 rs574023442 |
458 | T>K | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA6755087 rs574023442 COSM74871 |
458 | T>M | ovary Variant assessed as Somatic; 0.0 impact. large_intestine [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA6755090 rs76011019 |
461 | N>K | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA6755092 rs779268023 |
462 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA386340667 rs1313166446 |
466 | P>Q | No |
ClinGen TOPMed |
|
|
CA386340666 rs1215458030 |
466 | P>T | No |
ClinGen TOPMed |
|
| TCGA novel | 467 | S>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA386340679 rs1437497673 |
468 | L>V | No |
ClinGen gnomAD |
|
|
rs1223837874 CA386340694 |
469 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
CA386340719 rs1593608822 |
471 | N>H | No |
ClinGen Ensembl |
|
|
CA386340725 rs1221987951 |
471 | N>T | No |
ClinGen TOPMed |
|
|
rs750955842 CA6755093 |
475 | H>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA6755094 rs758850759 |
479 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA6755095 rs780515793 |
480 | V>M | No |
ClinGen ExAC gnomAD |
|
|
CA386340998 rs1490347642 |
482 | M>V | No |
ClinGen gnomAD |
|
|
CA386341052 rs1386269875 |
484 | R>W | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 486 | N>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1431994476 CA386341148 |
487 | E>K | No |
ClinGen gnomAD |
|
|
CA242559829 rs911883315 |
489 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
CA386341387 rs911883315 |
489 | P>R | No |
ClinGen TOPMed gnomAD |
|
|
rs780715408 CA242559842 |
491 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs780715408 CA6755117 |
491 | T>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA6755119 rs755840852 |
493 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs1273579970 CA386341479 |
496 | G>R | No |
ClinGen TOPMed |
|
| TCGA novel | 497 | V>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1555286923 CA6755120 |
500 | S>G | No |
ClinGen Ensembl |
|
|
rs777537217 CA6755122 |
503 | D>V | No |
ClinGen ExAC gnomAD |
|
|
CA242559856 rs765444385 |
509 | P>A | No |
ClinGen TOPMed gnomAD |
|
|
CA386341722 rs1204424729 |
513 | V>I | No |
ClinGen TOPMed gnomAD |
|
|
CA386341724 rs1204424729 |
513 | V>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1481831001 CA386341749 |
515 | S>G | No |
ClinGen gnomAD |
|
| TCGA novel | 516 | T>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA242559861 rs1032366323 |
516 | T>I | No |
ClinGen gnomAD |
|
|
CA6755126 rs745747989 |
517 | V>I | No |
ClinGen ExAC gnomAD |
|
|
CA386341796 rs1185554319 |
518 | S>P | No |
ClinGen gnomAD |
|
|
rs958006262 CA242559864 |
520 | T>I | No |
ClinGen TOPMed gnomAD |
|
|
rs768647176 CA6755127 |
522 | T>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA242559867 rs988199714 |
523 | M>V | No |
ClinGen gnomAD |
|
|
rs1352629117 CA386341877 |
524 | V>I | No |
ClinGen TOPMed gnomAD |
|
|
rs1331738667 CA386341954 |
528 | T>A | No |
ClinGen gnomAD |
|
|
rs761772896 CA6755129 |
528 | T>I | No |
ClinGen ExAC gnomAD |
|
|
rs765483436 CA6755130 |
529 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1309739535 CA386342130 |
535 | S>G | No |
ClinGen TOPMed gnomAD |
|
|
rs1475721623 CA386342140 |
535 | S>N | No |
ClinGen TOPMed |
|
|
rs1199708496 CA386342155 |
535 | S>R | No |
ClinGen gnomAD |
|
|
rs762532781 CA242559879 |
536 | T>I | No |
ClinGen Ensembl |
|
|
rs766670831 CA6755134 |
538 | G>W | No |
ClinGen ExAC gnomAD |
|
|
CA6755135 rs752039646 |
539 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs755466348 CA6755136 |
543 | D>V | No |
ClinGen ExAC gnomAD |
|
|
rs1593610229 CA386342345 |
544 | E>G | No |
ClinGen Ensembl |
|
|
CA386342379 rs1243909655 |
545 | T>I | No |
ClinGen gnomAD |
|
|
CA386342549 rs1190693816 |
551 | S>N | No |
ClinGen TOPMed |
|
|
CA6755137 rs767888932 |
552 | T>S | No |
ClinGen ExAC |
|
|
CA6755138 rs752291859 |
553 | K>N | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 556 | V>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs74623462 CA242560064 |
557 | D>A | No |
ClinGen ExAC gnomAD |
|
|
rs74623462 CA6755154 |
557 | D>V | No |
ClinGen ExAC gnomAD |
|
|
rs1042399443 CA242560069 |
560 | Y>H | No |
ClinGen gnomAD |
|
|
rs763634516 CA6755159 |
563 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA6755160 rs753573603 |
564 | A>T | No |
ClinGen ExAC gnomAD |
|
|
rs370973683 CA6755162 |
565 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs1275782898 CA386343093 |
566 | K>N | No |
ClinGen gnomAD |
|
|
CA386343100 rs1222269847 |
567 | I>M | No |
ClinGen gnomAD |
|
|
CA6755164 rs758122687 |
567 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs768655751 CA6755166 |
569 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA6755167 rs768655751 |
569 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA6755168 rs747743641 |
569 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA386343111 rs747743641 |
569 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1435897710 CA386343130 |
572 | T>I | No |
ClinGen gnomAD |
|
|
rs1308689742 CA386343137 |
573 | H>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1308689742 CA386343136 |
573 | H>R | No |
ClinGen TOPMed gnomAD |
|
|
rs1352358615 CA386343140 |
574 | A>T | No |
ClinGen gnomAD |
|
|
CA6755171 rs774432937 |
576 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA242560090 rs771532784 |
577 | T>M | No |
ClinGen gnomAD |
|
|
rs760006399 CA6755172 |
578 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs1565815294 CA386343180 |
579 | F>I | No |
ClinGen Ensembl |
|
| TCGA novel | 582 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA386343407 rs1385087162 |
583 | T>N | No |
ClinGen TOPMed gnomAD |
|
|
CA6755194 rs775671219 |
583 | T>P | No |
ClinGen ExAC gnomAD |
|
|
CA386343432 rs1343070546 |
584 | P>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA386343505 rs769324391 |
589 | A>P | No |
ClinGen ExAC gnomAD |
|
|
rs769324391 CA6755196 |
589 | A>T | No |
ClinGen ExAC gnomAD |
|
|
rs540566979 CA6755197 |
591 | V>A | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| TCGA novel | 592 | K>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
COSM200111 CA6755198 rs148983779 |
593 | A>V | large_intestine [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
CA242560551 rs1018663104 |
594 | G>E | No |
ClinGen Ensembl |
|
|
CA6755201 rs561923097 |
596 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
CA6755202 rs766033572 |
604 | F>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1443657088 CA386343725 |
604 | F>V | No |
ClinGen gnomAD |
|
|
rs1372016318 CA386343739 |
605 | K>E | No |
ClinGen TOPMed |
|
|
CA242560566 rs866706570 |
608 | T>K | No |
ClinGen Ensembl |
|
|
CA386343825 rs1373040710 |
611 | V>M | No |
ClinGen TOPMed gnomAD |
|
|
rs1474700648 CA386343850 |
614 | F>Y | No |
ClinGen gnomAD |
|
| TCGA novel | 618 | P>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1424778105 CA386343875 |
618 | P>T | No |
ClinGen gnomAD |
|
| TCGA novel | 619 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs199552084 CA242560573 |
623 | S>N | No |
ClinGen 1000Genomes gnomAD |
|
|
CA386344616 rs1466728629 |
628 | G>V | No |
ClinGen gnomAD |
|
|
CA386344647 rs1355410097 |
633 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs772548086 CA6755218 |
634 | D>E | No |
ClinGen ExAC gnomAD |
|
|
CA386344662 rs1283186479 |
635 | Y>C | No |
ClinGen TOPMed |
|
|
CA386344676 rs1401853075 |
637 | L>S | No |
ClinGen gnomAD |
|
|
rs1299980441 CA386344687 |
639 | K>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs1593614438 CA386344707 |
641 | Q>R | No |
ClinGen Ensembl |
|
|
CA386344732 rs1340999399 |
645 | P>A | No |
ClinGen gnomAD |
|
|
rs762495245 CA6755219 |
646 | G>D | No |
ClinGen ExAC gnomAD |
|
|
rs748369209 CA242561859 |
653 | V>I | No |
ClinGen Ensembl |
|
|
CA386344804 rs1233515525 |
656 | I>N | No |
ClinGen gnomAD |
|
|
CA6755221 rs773982002 |
657 | N>S | No |
ClinGen ExAC gnomAD |
|
|
rs1329661057 CA386344815 |
658 | G>S | No |
ClinGen TOPMed |
|
|
rs759341408 CA6755222 |
663 | P>A | No |
ClinGen ExAC gnomAD |
|
|
CA242561890 rs868443435 |
663 | P>H | No |
ClinGen Ensembl |
|
|
CA386344879 rs1593614485 COSM1209352 |
667 | I>V | large_intestine [Cosmic] | No |
ClinGen cosmic curated Ensembl |
|
CA386344885 rs1308037218 |
668 | S>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA6755224 rs375199545 |
671 | K>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1296415917 CA386344939 |
675 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
| TCGA novel | 681 | P>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA386344989 rs1197780271 |
683 | A>S | No |
ClinGen gnomAD |
|
|
CA6755226 rs764073895 |
684 | V>I | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 688 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1460649084 CA386345062 |
692 | G>D | No |
ClinGen TOPMed |
|
|
CA6755274 rs775199757 |
692 | G>S | No |
ClinGen ExAC gnomAD |
|
|
CA6755275 rs760440803 |
696 | S>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs372296703 CA6755276 |
701 | T>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs761768406 CA6755278 |
703 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1182866482 CA386345141 |
704 | S>F | No |
ClinGen TOPMed |
|
|
CA386345136 rs1351494153 |
704 | S>T | No |
ClinGen gnomAD |
|
|
CA6755280 rs751737486 |
711 | S>* | No |
ClinGen ExAC gnomAD |
|
|
rs375511576 CA6755279 |
711 | S>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1193917539 CA386345194 |
712 | A>G | No |
ClinGen TOPMed |
|
|
CA6755281 rs759685259 |
716 | I>L | No |
ClinGen ExAC gnomAD |
|
|
CA6755282 rs767910383 |
717 | R>C | No |
ClinGen ExAC gnomAD |
|
|
CA386345254 rs1381412283 |
721 | I>M | No |
ClinGen gnomAD |
|
|
rs2731021 CA242562474 |
722 | Q>H | No |
ClinGen Ensembl |
|
|
rs1398547370 CA386345255 |
722 | Q>K | No |
ClinGen Ensembl |
|
|
rs1226064830 CA386345268 |
723 | D>E | No |
ClinGen TOPMed gnomAD |
|
|
CA6755283 rs752908767 COSM3728095 |
723 | D>N | haematopoietic_and_lymphoid_tissue [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed |
|
CA386345298 rs756441569 |
727 | Q>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1356594809 CA386345319 |
730 | F>Y | No |
ClinGen TOPMed |
|
|
rs559361222 CA242562480 |
733 | I>V | No |
ClinGen 1000Genomes |
|
|
rs1322809745 CA386345383 |
735 | C>G | No |
ClinGen gnomAD |
|
|
CA386345400 rs1313743239 |
736 | G>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA386345455 rs1565817456 |
741 | C>R | No |
ClinGen Ensembl |
|
|
rs1459312303 CA386345474 |
742 | I>M | No |
ClinGen gnomAD |
|
|
rs2930861 CA6755286 |
742 | I>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA6755287 rs757814858 |
745 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1460052838 CA386345516 |
746 | G>A | No |
ClinGen gnomAD |
|
|
CA386345508 rs1242697272 |
746 | G>R | No |
ClinGen gnomAD |
|
|
rs1415923388 CA386345538 |
748 | L>V | No |
ClinGen gnomAD |
|
|
rs1294285350 CA386345571 |
751 | A>T | No |
ClinGen TOPMed |
|
|
rs1459666075 CA386345605 |
753 | I>T | No |
ClinGen TOPMed |
|
|
rs779584088 CA6755291 |
756 | T>I | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 756 | T>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 756 | T>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1593615251 CA386345649 |
757 | S>P | No |
ClinGen Ensembl |
|
|
CA386345659 rs1593615262 |
758 | R>G | No |
ClinGen Ensembl |
|
|
CA386345666 rs1593615267 |
758 | R>S | No |
ClinGen Ensembl |
|
|
CA386345688 rs1331631602 |
760 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
rs746602412 CA6755292 |
761 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs958144915 CA242562504 |
762 | V>A | No |
ClinGen Ensembl |
|
| TCGA novel | 764 | R>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA6755293 rs772818139 COSM281631 |
768 | K>N | large_intestine [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
CA6755295 rs761677309 |
775 | P>L | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 775 | P>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA386345920 rs1219577136 |
779 | V>A | No |
ClinGen gnomAD |
|
|
CA386345929 rs1262786480 |
780 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA242562521 rs950318999 |
786 | N>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA242562522 rs1041891214 |
789 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
CA6755297 rs773269246 |
790 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA242562528 rs903381363 |
791 | L>* | No |
ClinGen TOPMed gnomAD |
No associated diseases with Q9Y5Z7
2 regional properties for Q9Y5Z7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Fibronectin type III | 357 - 675 | IPR003961-1 |
| domain | Fibronectin type III | 678 - 778 | IPR003961-2 |
10 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| histone methyltransferase complex | A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins. |
| MLL1 complex | A protein complex that can methylate lysine-4 of histone H3. MLL1/MLL is the catalytic methyltransferase subunit, and the complex also contains the core components ASH2L, HCFC1/HCF1 WDR5 and RBBP5. |
| MLL1/2 complex | A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL1 or MLL2 in human, or equivalent in other species. |
| nuclear body | Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins. |
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| Set1C/COMPASS complex | A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p; in mammals it contains the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| transcription coactivator activity | A transcription coregulator activity that activates or increases the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coactivators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator. |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| chromatin remodeling | A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication. |
| histone H3-K4 methylation | The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone. |
| negative regulation of transcription by RNA polymerase II | Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. |
| regulation of DNA-templated transcription | Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
| viral process | A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q5RKG2 | Hcfc2 | Host cell factor 2 | Rattus norvegicus (Rat) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAAPSLLNWR | RVSSFTGPVP | RARHGHRAVA | IRELMIIFGG | GNEGIADELH | VYNTATNQWF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LPAVRGDIPP | GCAAHGFVCD | GTRILVFGGM | VEYGRYSNEL | YELQASRWLW | KKVKPHPPPS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GLPPCPRLGH | SFSLYGNKCY | LFGGLANESE | DSNNNVPRYL | NDFYELELQH | GSGVVGWSIP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VTKGVVPSPR | ESHTAVIYCK | KDSGSPKMYV | FGGMCGARLD | DLWQLDLETM | SWSKPETKGT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VPLPRSLHTA | SVIGNKMYIF | GGWVPHKGEN | TETSPHDCEW | RCTSSFSYLN | LDTTEWTTLV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SDSQEDKKNS | RPRPRAGHCA | VAIGTRLYFW | SGRDGYKKAL | NSQVCCKDLW | YLDTEKPPAP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SQVQLIKATT | NSFHVKWDEV | STVEGYLLQL | STDLPYQAAS | SDSSAAPNMQ | GVRMDPHRQG |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SNNIVPNSIN | DTINSTKTEQ | PATKETSMKN | KPDFKALTDS | NAILYPSLAS | NASNHNSHVV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| DMLRKNEGPH | TSANVGVLSS | CLDVRTVIPE | TSVSSTVSST | QTMVTQQTIK | TESSSTNGAV |
| 550 | 560 | 570 | 580 | 590 | 600 |
| VKDETSLTTF | STKSEVDETY | ALPATKISRV | ETHATATPFS | KETPSNPVAT | VKAGERQWCD |
| 610 | 620 | 630 | 640 | 650 | 660 |
| VGIFKNNTAL | VSQFYLLPKG | KQSISKVGNA | DVPDYSLLKK | QDLVPGTGYR | FRVAAINGCG |
| 670 | 680 | 690 | 700 | 710 | 720 |
| IGPFSKISEF | KTCIPGFPGA | PSAVRISKNV | EGIHLSWEPP | TSPSGNILEY | SAYLAIRTAQ |
| 730 | 740 | 750 | 760 | 770 | 780 |
| IQDNPSQLVF | MRIYCGLKTS | CIVTAGQLAN | AHIDYTSRPA | IVFRISAKNE | KGYGPATQVR |
| 790 | |||||
| WLQGNNKKAP | LN |