Q9XWU8
Gene name |
epg-3 |
Protein name |
Ectopic P granules protein 3 |
Names |
|
Species |
Caenorhabditis elegans |
KEGG Pathway |
cel:CELE_Y37D8A.22 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9XWU8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9XWU8-F1 | Predicted | AlphaFoldDB |
No variants for Q9XWU8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9XWU8 | |||||
No associated diseases with Q9XWU8
No regional properties for Q9XWU8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9XWU8 | |||
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| endomembrane system | A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. |
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| autophagy | The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation. |
| Golgi organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus. |
| macroautophagy | The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded. |
| negative regulation of autophagosome assembly | Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome assembly. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| F4I8Q7 | KMS2 | Vacuole membrane protein KMS2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAKKQKKSTE | KSERTVEFKE | PPKPANSEER | LKPAGRGMKP | SPSQNTLNRM | ERETIVFWRR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PHIVIPYALM | EIAHLAVELF | FKILAHKTVL | LLTAISIGLA | VYGYHAPGAH | QEHVQTIEKH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ILWWSWWVLL | GVLSSIGLGS | GLHTFLIYLG | PHIAAVTMAA | YECQSLDFPQ | PPYPESIQCP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| STKSSIAVTF | WQIVAKVRVE | SLLWGAGTAL | GELPPYFMAR | AARISGQEPD | DEEYREFLEL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MNADKESDAD | QKLSIVERAK | SWVEHNIHRL | GFPGILLFAS | IPNPLFDLAG | ITCGHFLVPF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| WSFFGATLIG | KALVKMHVQM | GFVILAFSDH | HAENFVKILE | KIPAVGPYIR | QPISDLLEKQ |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RKALHKTPGE | HSEQSTSYLA | WGLSLMVTFM | ILFFFLSIVN | SLAKDYHKRL | WERKRRQNKD |
| 430 | 440 | 450 | |||
| LIDEENQSFE | EEEEEAVTPP | SSCPLLLSDG | FEGVVVKK |