Q9XTT8

PR
Gene name
pph-4.2
Protein name
Serine/threonine-protein phosphatase 4 catalytic subunit 2
Names
PP4C-2
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_Y49E10.3
EC number
3.1.3.16: Phosphoric monoester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

268-321 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9XTT8

Entry ID Method Resolution Chain Position Source
AF-Q9XTT8-F1 Predicted AlphaFoldDB

No variants for Q9XTT8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9XTT8

No associated diseases with Q9XTT8

2 regional properties for Q9XTT8

Type Name Position InterPro Accession
domain Calcineurin-like phosphoesterase domain, ApaH type 58 - 250 IPR004843
domain Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase 30 - 304 IPR006186

Functions

Description
EC Number 3.1.3.16 Phosphoric monoester hydrolases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
myosin phosphatase activity Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate.
protein serine/threonine phosphatase activity Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.

1 GO annotations of biological process

Name Definition
double-strand break repair via homologous recombination The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9XW79 pph-4.1 Serine/threonine-protein phosphatase 4 catalytic subunit 1 Caenorhabditis elegans PR
10 20 30 40 50 60
MLEEDAAGPD QLGPNDLDRQ IEIAMRCELI CETQVKSICA KVREILIEEA NVQVIDTPVT
70 80 90 100 110 120
ICGDIHGQFH DLMELFRVGG SPPNTNYLFL GDYVDRGYNS VETFILLMLL KCRYPDRITL
130 140 150 160 170 180
IRGNHESRQI TQVYGFYDEC VRKYGSGQVW KHCTEIFDYL SLAAVIDGKL FCVHGGLSPS
190 200 210 220 230 240
IATLDQIRVL DRKIEVPHEG PMCDLLWSDP EEGCSGWGIS PRGAGYLFGG DAAELFCENN
250 260 270 280 290 300
DFLRICRAHQ LVMEGYKLHF RKRVVTVWSA PNYCYRCGNV AAIMEVTEEN IDSDPVFEVF
310 320
EAATVENRGE PKKQPIAQYF L