Q9XI74
Gene name |
PUMP3 (UCP3, At1g14140, F7A19.22) |
Protein name |
Mitochondrial uncoupling protein 3 |
Names |
AtPUMP3 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G14140 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9XI74
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9XI74-F1 | Predicted | AlphaFoldDB |
39 variants for Q9XI74
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH11187327 | 14 | T>S | No | 1000Genomes | |
| ENSVATH11187326 | 19 | A>P | No | 1000Genomes | |
| ENSVATH04574222 | 24 | M>I | No | 1000Genomes | |
| ENSVATH04574221 | 25 | V>I | No | 1000Genomes | |
| ENSVATH11187325 | 27 | E>D | No | 1000Genomes | |
| tmp_1_4839523_T_C | 27 | E>G | No | 1000Genomes | |
| ENSVATH04574220 | 43 | H>Y | No | 1000Genomes | |
| ENSVATH11187214 | 46 | G>E | No | 1000Genomes | |
| ENSVATH11187213 | 57 | F>I | No | 1000Genomes | |
| ENSVATH11187212 | 66 | K>N | No | 1000Genomes | |
| ENSVATH11187211 | 70 | I>S | No | 1000Genomes | |
| tmp_1_4839395_T_C | 70 | I>V | No | 1000Genomes | |
| tmp_1_4839392_C_T | 71 | G>S | No | 1000Genomes | |
| ENSVATH04574219 | 72 | L>F | No | 1000Genomes | |
| ENSVATH11187209 | 75 | G>D | No | 1000Genomes | |
| ENSVATH07512718 | 78 | P>S | No | 1000Genomes | |
| ENSVATH01049437 | 79 | A>E | No | 1000Genomes | |
| ENSVATH00022751 | 93 | G>A | No | 1000Genomes | |
| ENSVATH04574216 | 107 | N>K | No | 1000Genomes | |
| tmp_1_4839265_G_A | 113 | P>L | No | 1000Genomes | |
| tmp_1_4838648_G_A | 134 | P>L | No | 1000Genomes | |
| ENSVATH04574187 | 149 | V>M | No | 1000Genomes | |
| ENSVATH13894340 | 155 | P>L | No | 1000Genomes | |
| tmp_1_4838586_G_A | 155 | P>S | No | 1000Genomes | |
| ENSVATH04574183 | 170 | S>A | No | 1000Genomes | |
| tmp_1_4838490_C_T | 187 | A>T | No | 1000Genomes | |
| ENSVATH11187039 | 209 | K>E | No | 1000Genomes | |
| ENSVATH11187038 | 209 | K>R | No | 1000Genomes | |
| tmp_1_4838415_C_G | 212 | E>Q | No | 1000Genomes | |
| tmp_1_4838375_G_A | 225 | S>L | No | 1000Genomes | |
| tmp_1_4838373_C_T | 226 | G>S | No | 1000Genomes | |
| ENSVATH04574179 | 231 | S>T | No | 1000Genomes | |
| ENSVATH11187037 | 232 | L>W | No | 1000Genomes | |
| ENSVATH04574178 | 253 | R>S | No | 1000Genomes | |
| tmp_1_4838285_G_A | 255 | S>F | No | 1000Genomes | |
| ENSVATH04574177 | 264 | K>R | No | 1000Genomes | |
| ENSVATH00022747 | 279 | W>* | No | 1000Genomes | |
| tmp_1_4838192_T_A | 286 | Q>L | No | 1000Genomes | |
| ENSVATH11187036 | 288 | V>L | No | 1000Genomes |
No associated diseases with Q9XI74
3 regional properties for Q9XI74
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Mitochondrial substrate/solute carrier | 12 - 103 | IPR018108-1 |
| repeat | Mitochondrial substrate/solute carrier | 112 - 208 | IPR018108-2 |
| repeat | Mitochondrial substrate/solute carrier | 213 - 299 | IPR018108-3 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrial inner membrane | The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| transmembrane transporter activity | Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| mitochondrial transport | Transport of substances into, out of or within a mitochondrion. |
| response to cold | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| O95847 | SLC25A27 | Mitochondrial uncoupling protein 4 | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MERSRVTREA | PTGTRILLAS | LSAMVAESVT | FPIDLTKTRM | QLHGSGSASG | AHRIGAFGVV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SEIARKEGVI | GLYKGLSPAI | IRHLFYTPIR | IIGYENLKGL | IVRSETNNSE | SLPLATKALV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GGFSGVIAQV | VASPADLVKV | RMQADGRLVS | QGLKPRYSGP | IEAFTKILQS | EGVKGLWKGV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LPNIQRAFLV | NMGELACYDH | AKHFVIDKKI | AEDNIFAHTL | ASIMSGLAST | SLSCPADVVK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TRMMNQGENA | VYRNSYDCLV | KTVKFEGIRA | LWKGFFPTWA | RLGPWQFVFW | VSYEKFRLLA |
| GISSF |