Q9WUF1

PR
Gene name
Vmn1r49 (V1rb2)
Protein name
Vomeronasal type-1 receptor 49
Names
Vomeronasal receptor VRi2, Vomeronasal type-1 receptor B2
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:24112
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

190-263 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9WUF1

Entry ID Method Resolution Chain Position Source
AF-Q9WUF1-F1 Predicted AlphaFoldDB

36 variants for Q9WUF1

Variant ID(s) Position Change Description Diseaes Association Provenance
rs50970796 8 H>N No EVA
rs1133644698 29 T>S No EVA
rs30866568 35 R>H No EVA
rs3388822506 42 E>D No EVA
rs3388830024 65 T>S No EVA
rs3388837545 71 V>M No EVA
rs261987134 81 N>D No EVA
rs3388830022 90 Y>F No EVA
rs3388829979 101 S>P No EVA
rs3388851020 109 L>R No EVA
rs583546849 115 S>C No EVA
rs3388837569 129 P>S No EVA
rs3388837569 129 P>T No EVA
rs244167898 151 L>F No EVA
rs227152499 152 V>I No EVA
rs3412732399 154 I>F No EVA
rs252902734 156 V>A No EVA
rs3388845116 180 S>F No EVA
rs3388822454 186 S>T No EVA
rs3388851056 194 T>N No EVA
rs3388829986 201 A>T No EVA
rs233797915 203 S>F No EVA
rs3388845626 217 Q>L No EVA
rs3397035118 227 S>* No EVA
rs3396781753 227 S>C No EVA
rs221015969 228 S>P No EVA
rs250997652 231 S>F No EVA
rs3396615164 238 R>W No EVA
rs231934824 244 T>M No EVA
rs213770981 247 F>S No EVA
rs3413040994 254 E>G No EVA
rs3388845575 260 S>T No EVA
rs3388849564 293 E>D No EVA
rs3388851054 295 H>R No EVA
rs3388843140 297 I>V No EVA
rs249558571 300 W>C No EVA

No associated diseases with Q9WUF1

1 regional properties for Q9WUF1

Type Name Position InterPro Accession
domain GPCR, rhodopsin-like, 7TM 27 - 289 IPR017452

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
pheromone receptor activity Combining with a pheromone to initiate a change in cell activity. A pheromone is a substance used in olfactory communication between organisms of the same species eliciting a change in sexual or social behavior.

2 GO annotations of biological process

Name Definition
response to pheromone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus.
sensory perception of chemical stimulus The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9EP51 Vmn1r50 Vomeronasal type-1 receptor 50 Mus musculus (Mouse) PR
10 20 30 40 50 60
MSKANLLHTD NNMKIILFSE VSVGISANTI LFFARLCKLL GENKPKPIDL YIAFLSLTQL
70 80 90 100 110 120
MLLITMGLIA VDMFMPWGRW NSTTCQSLIY LHRLLRGLAL SATCLLNVLW TITLSSRSSC
130 140 150 160 170 180
LTKFKHKSPH HISGAFLFFY VLYMSFSSHV LVSIIVTPNL TSEDFMYVTQ SCSLLPMSYS
190 200 210 220 230 240
RESRFSTLMA IRETFLISLM ALSSGYMVAL LWRHKKQAQH LRSTSLSSKA SPEQRATRTI
250 260 270 280 290 300
MLLTSLFVVL YILERVVFQS RLKFKDCSVF YFVHIIMSHS YATVSPFVFI CTEKHIIKFW
ESIFGRIVNI