Q9VY99

PR
Gene name
Nna1
Protein name
Cytosolic carboxypeptidase Nna1
Names
Nervous system nuclear protein induced by axotomy protein 1 homolog
Species
Drosophila melanogaster (Fruit fly)
KEGG Pathway
dme:Dmel_CG44533
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

235-307 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9VY99

Entry ID Method Resolution Chain Position Source
AF-Q9VY99-F1 Predicted AlphaFoldDB

No variants for Q9VY99

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9VY99

No associated diseases with Q9VY99

2 regional properties for Q9VY99

Type Name Position InterPro Accession
domain Peptidase M14, carboxypeptidase A 893 - 1112 IPR000834
domain Cytosolic carboxypeptidase, N-terminal 735 - 870 IPR040626

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

2 GO annotations of molecular function

Name Definition
metallocarboxypeptidase activity Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
zinc ion binding Binding to a zinc ion (Zn).

4 GO annotations of biological process

Name Definition
larval development The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters.
mitochondrion organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
protein side chain deglutamylation The removal of a glutamate residue from the side chain of a protein. Glutamate side chains are added to glutamic acid residues within the primary protein sequence during polyglutamylation.
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O76373 ccpp-1 Cytosolic carboxypeptidase 1 Caenorhabditis elegans PR
10 20 30 40 50 60
MAEREREAMS ASLSRLLRTL SSASMSRRHC PLALLQPIPL HQSEIALGSA SSGGSAERCC
70 80 90 100 110 120
SSCSDDSNNN ERCKSAERGT AADEVGEEGR EEVELESKED AVEGEQDELE LKRDSSTVNV
130 140 150 160 170 180
NVVRANFKCN DMECSLVLGD YVNGFLGSFL SKGLKTNQLV VNTDEKTLRP VARLKEPRDL
190 200 210 220 230 240
FALPKDKDND CSQQAPRWPV ECQVIEERII HIPYVPAVPE PLNAPTGNEL KPRPVGEENG
250 260 270 280 290 300
IVVFSYSPIS AVNYEKPKAK KEDDESSDES DYSSDSRQDS TPPSRSTPMR LAGGGECAPG
310 320 330 340 350 360
KLNSVSKMIN NVDNRSTSAS LDDNDDYYDD EYDTSGGYCG GSGEAKEKAI IKDLIEAKKK
370 380 390 400 410 420
RYQEEAEVTP VGGGTARNSR AASRSEASKD ASDIDDIWKN NTSEYKPASP RYVLSQFGKN
430 440 450 460 470 480
VTKAVIDRIV DHEDLVPPSG SQKVSNQFAV GPVKLPKTNI ARLEVAFERS ACQDRSKSRL
490 500 510 520 530 540
KKKMSSSRRR RESTSDEDSS SSSLGNEEDE EVDDSDSDAE NTGSGIGLRR ILGSYSARLA
550 560 570 580 590 600
GGAEKCPCPG SGSVSDTETL VGDESRSRLA GSNGLHQQDV VCSRNRQAQS RSPLRSVPHT
610 620 630 640 650 660
HAATVAAAAA ALARGRNRDK DGCLGGKDEK NMGMGVGTTG TSSMGTRTSS PVRNNVFRLS
670 680 690 700 710 720
KDQHILLNSM TSQETTGTLI SSTSTNQTTT TTNSSQSFLC SDLPQAQFSR SAVGGARFMT
730 740 750 760 770 780
NCHPMNPEEY DGLEFESRFE SGNLAKAVQI TPTYYELYLR PDLYTSRSKQ WFYFRVRRTR
790 800 810 820 830 840
RKMLYRFSIV NLVKSDSLYN DGMQPVMYST LGAKEKSEGW RRCGDNICYY RNDDESASSS
850 860 870 880 890 900
ANEDDEDNST YTLTFTIEFE HDDDTVFFAH SYPYTYSDLQ DYLMEIQRHP VKSKFCKLRL
910 920 930 940 950 960
LCRTLAGNNV YYLTVTAPSS NEENMRRKKS IVVSARVHPS ETPASWMMKG LMDFITGDTT
970 980 990 1000 1010 1020
VAKRLRHKFI FKLVPMLNPD GVIVGNTRNS LTGKDLNRQY RTVIRETYPS IWYTKAMIRR
1030 1040 1050 1060 1070 1080
LIEECGVAMY CDMHAHSRKH NIFIYGCENK RNPEKKLTEQ VFPLMLHKNS ADRFSFESCK
1090 1100 1110 1120 1130 1140
FKIQRSKEGT GRIVVWMLGI TNSYTIEASF GGSSLGSRKG THFNTQDYEH MGRAFCETLL
1150 1160 1170 1180 1190 1200
DYCDENPNKV KRHAKLFKQI KKIRKREKRE QKALKLQKMA DQGCIMNDKL KVKRSVEKSV
S