Q9VC57
PR
Gene name |
atl (CG6668) |
Protein name |
Atlastin |
Names |
|
Species |
Drosophila melanogaster (Fruit fly) |
KEGG Pathway |
dme:Dmel_CG6668 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for Q9VC57
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 3X1D | X-ray | 287 A | A | 1-541 | PDB |
| AF-Q9VC57-F1 | Predicted | AlphaFoldDB |
No variants for Q9VC57
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9VC57 | |||||
No associated diseases with Q9VC57
Functions
8 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| endomembrane system | A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. |
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| intrinsic component of endoplasmic reticulum membrane | The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| guanyl ribonucleotide binding | Binding to a guanyl ribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. |
| identical protein binding | Binding to an identical protein or proteins. |
12 GO annotations of biological process
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane fusion | The joining of 2 or more lipid bilayer membranes that surround the endoplasmic reticulum. |
| endoplasmic reticulum organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum. |
| Golgi organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus. |
| membrane fusion | The membrane organization process that joins two lipid bilayers to form a single membrane. |
| microtubule depolymerization | The removal of tubulin heterodimers from one or both ends of a microtubule. |
| muscle organ development | The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work. |
| neuromuscular junction development | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction. |
| positive regulation of axon extension involved in regeneration | Any process that activates, maintains or increases the rate of axon extension involved in regeneration. |
| protein homooligomerization | The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer. |
| regulation of microtubule depolymerization | Any process that modulates the frequency, rate or extent of microtubule depolymerization. |
| regulation of synaptic assembly at neuromuscular junction | Any process that modulates the frequency, rate or extent of synaptic assembly at neuromuscular junctions. |
| synaptic assembly at neuromuscular junction | The assembly of a synapse at a neuromuscular junction. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGGSAVQVIN | ASEEHTFVLN | EDALSEVLMR | DEVKDRFVCV | VSVAGAFRKG | KSFLLDFFLR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YMYSKYVHHD | ATDWLGGESD | PLEGFSWRGG | SERDTTGILM | WSDIFLHDYP | NGDKIAIILL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DTQGAFDSQS | TVRDCATVFA | LSTMLSSVQI | YNLSQNIQED | DLQHLQLFTE | YGRLALADTG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KKPFQRLQFL | VRDWSFPYEA | EYGALGGDKI | LKRRLEVSDK | QHPELQSLRR | HISSCFTEVA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| CFLMPHPGLN | VATNPKFDGR | LQDITPEFKS | SLRSLVPMLL | APDNLVYKEI | SGQRVRARDL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IQYFQSYMNI | YKGNELPEPK | SMLVATAEAN | HLTAVAAAKE | LYGQLMEEVC | GGTRPYLSTA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| HLQTEHLRVK | DKALFQFAAK | RKMGGEEFTE | KFRKQLEDDL | EEVFTNYQAH | NESKNIFKAA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| RTPAVYFACA | VIMYILSGIF | GLVGLYTFAN | FCNLVMGVAL | LTLALWAYIR | YSGELSDFGG |
| 490 | 500 | 510 | 520 | 530 | 540 |
| KLDDFATLLW | EKFMRPIYHG | CMEKGIHHVA | THATEMAVGG | GAASYRSQTS | VNASNGKVKR |
| S |