AiPD: Autoinhibited Protein Database

Q9UN86

Gene name	G3BP2 (KIAA0660)
Protein name	Ras GTPase-activating protein-binding protein 2
Names	G3BP-2, GAP SH3 domain-binding protein 2
Species	Homo sapiens (Human)
KEGG Pathway	hsa:9908
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

107-274 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

107-274 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

2 structures for Q9UN86

Entry ID	Method	Resolution	Chain	Position	Source
5DRV	X-ray	275 A	A	1-139	PDB
AF-Q9UN86-F1	Predicted				AlphaFoldDB

215 variants for Q9UN86

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
rs753193049 CA2965864	8	P>L		No	ClinGen ExAC TOPMed gnomAD
CA357285319 rs1560620881	8	P>T		No	ClinGen Ensembl
CA357285288 rs1316139548	13	R>Q		No	ClinGen gnomAD
CA2965859 rs761045470	22	L>S		No	ClinGen ExAC gnomAD
CA2965857 rs548893827	29	Y>C		No	ClinGen 1000Genomes ExAC gnomAD
TCGA novel	32	R>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs78721699 CA2965828	37	N>D		No	ClinGen ExAC gnomAD
CA2965826 rs760203918 CA2965827	37	N>K		No	ClinGen ExAC gnomAD
CA2965824 rs772886543	38	S>F		No	ClinGen ExAC
CA2965823 rs771668396	39	S>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA
CA2965821 rs769146453	40	Y>F		No	ClinGen ExAC
CA2965820 rs769146453	40	Y>S		No	ClinGen ExAC
CA2965819 rs749753720	42	H>L		No	ClinGen ExAC gnomAD
COSM1057566 CA357285080 rs749753720	42	H>R	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
CA2965818 rs574345924	43	G>R		No	ClinGen 1000Genomes ExAC
CA99771168 rs898328137	45	V>G		No	ClinGen Ensembl
rs1480509432 CA357285044	48	S>G		No	ClinGen gnomAD
rs756221673 CA2965817	48	S>N		No	ClinGen ExAC gnomAD
TCGA novel	65	V>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs267600258 CA99770108 COSM141086	78	R>C	upper_aerodigestive_tract large_intestine Variant assessed as Somatic; impact. skin [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated Ensembl NCI-TCGA
CA357284431 rs1352742071	78	R>H		No	ClinGen gnomAD
rs1166198130 CA357284398	83	H>Y		No	ClinGen TOPMed
CA357284372 rs1397108294	87	S>G		No	ClinGen TOPMed
CA2965789 rs766878865	88	D>G		No	ClinGen ExAC gnomAD
rs1334099676 CA357284343	91	V>A		No	ClinGen TOPMed
rs761408391 CA2965788	97	L>V		No	ClinGen ExAC gnomAD
rs369466216 CA2965787	101	S>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA2965785 rs140413061	103	Q>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	115	A>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1185000405 CA357284129	121	P>A		No	ClinGen gnomAD
TCGA novel	121	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA357284130 rs1185000405	121	P>T		No	ClinGen gnomAD
CA357284112 rs1242801096	122	N>K		No	ClinGen TOPMed gnomAD
TCGA novel	129	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs765465830 CA2965764	132	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
TCGA novel	132	R>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	133	Y>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1448699500 CA357283937	137	V>L		No	ClinGen TOPMed gnomAD
CA357283907 rs1578391226	140	D>H		No	ClinGen Ensembl
TCGA novel	145	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA357283850 rs1341217176	145	L>P		No	ClinGen gnomAD
rs905452735 CA99769545	146	D>G		No	ClinGen Ensembl
CA2965740 rs773718595	149	S>P		No	ClinGen ExAC gnomAD
CA2965741 rs773718595	149	S>T		No	ClinGen ExAC gnomAD
CA2965739 rs772089002	150	E>D		No	ClinGen ExAC TOPMed gnomAD
CA357283760 rs1355427733	150	E>Q		No	ClinGen TOPMed
rs761910810 CA2965738	151	D>N		No	ClinGen ExAC TOPMed gnomAD
rs774406006 CA2965737	153	V>A		No	ClinGen ExAC gnomAD
CA357283730 rs1374189458	154	E>G		No	ClinGen TOPMed
rs768971598 CA2965736 CA357283712	156	E>D		No	ClinGen ExAC TOPMed gnomAD
CA357283714 rs1468238767	156	E>G		No	ClinGen gnomAD
CA2965735 rs745638771	157	Q>E		No	ClinGen ExAC gnomAD
CA357283695 rs1358125520	159	E>K		No	ClinGen TOPMed
CA2965733 rs535899085	161	Q>E		No	ClinGen 1000Genomes ExAC gnomAD
rs746886063 CA2965731	166	P>T		No	ClinGen ExAC TOPMed gnomAD
rs1236463614 CA357283617	170	N>S		No	ClinGen gnomAD
rs1182897190 CA357283609	171	A>G		No	ClinGen gnomAD
CA357283603 rs1438364937	172	N>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA2965730 rs777878492	173	S>C		No	ClinGen ExAC TOPMed gnomAD
CA357283598 rs777878492	173	S>G		No	ClinGen ExAC TOPMed gnomAD
rs568443932 CA2965728	175	Y>F		No	ClinGen 1000Genomes ExAC gnomAD
CA99768437 rs768895465	176	Y>C		No	ClinGen TOPMed gnomAD
rs747704973 CA2965727	176	Y>H		No	ClinGen ExAC gnomAD
CA357283521 rs1450693641	179	H>Q		No	ClinGen gnomAD
rs754723418 CA2965725	179	H>Y		No	ClinGen ExAC gnomAD
CA2965724 rs753433649	180	P>S		No	ClinGen ExAC gnomAD
rs766706389 CA2965723	182	T>I		No	ClinGen ExAC TOPMed gnomAD
rs1383556633 CA357283387	185	I>L		No	ClinGen TOPMed
CA2965707 COSM1207734 rs754457045	187	E>D	large_intestine [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
rs964918593 CA99768049	188	P>R		No	ClinGen TOPMed
rs1560615211 CA357283352	188	P>T		No	ClinGen Ensembl
TCGA novel	190	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA357283320 rs1310724610	190	E>G		No	ClinGen TOPMed
rs371079826 CA2965704	194	H>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs371262968 CA2965701	198	P>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA357283171 rs1560615120	201	E>K		No	ClinGen Ensembl
rs146775757 CA2965699	203	E>G		No	ClinGen ExAC TOPMed gnomAD
rs376865388 CA2965698	206	T>N		No	ClinGen ESP ExAC TOPMed gnomAD
CA2965697 rs191522721	207	E>D		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA357283051 rs1362625488	209	L>P		No	ClinGen Ensembl
TCGA novel	212	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs765599561 CA2965696	213	V>A		No	ClinGen ExAC gnomAD
CA357282984 rs1488900350	214	E>G		No	ClinGen gnomAD
rs1578388251 CA357282957	216	K>E		No	ClinGen Ensembl
CA357282900 rs1430163815	219	E>D		No	ClinGen TOPMed
CA2965693 rs748840062	219	E>Q		No	ClinGen ExAC gnomAD
rs1324953153 CA357282867	222	E>K		No	ClinGen gnomAD
CA2965689 rs748788122	225	S>T		No	ClinGen ExAC gnomAD
rs769494348 CA2965687	226	T>A		No	ClinGen ExAC TOPMed gnomAD
CA357282798 rs1426245128	226	T>S		No	ClinGen gnomAD
CA2965686 rs746226623	227	T>P		No	ClinGen ExAC TOPMed gnomAD
rs199958799 CA2965685	228	P>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA99767815 rs898305768	229	P>L		No	ClinGen Ensembl
CA99767835 rs149145617	229	P>S		No	ClinGen ESP
rs187093571 CA2965684	230	P>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1460133857 CA357282757	230	P>S		No	ClinGen gnomAD
CA357282749 rs1170517222	231	A>T		No	ClinGen gnomAD
rs1479831764 CA357282728	233	P>T		No	ClinGen gnomAD
CA2965680 rs778176701	234	V>G		No	ClinGen ExAC gnomAD
rs1301098559 CA357282724	234	V>I		No	ClinGen TOPMed
CA2965679 rs758475466	235	S>P		No	ClinGen ExAC gnomAD
rs765546547 CA2965677	237	P>S		No	ClinGen ExAC gnomAD
TCGA novel	238	Q>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA2965675 rs754122102	238	Q>R		No	ClinGen ExAC gnomAD
rs767370083 CA2965674	240	P>L		No	ClinGen ExAC gnomAD
TCGA novel	243	A>=	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA357282603 rs1261313799	251	S>C		No	ClinGen gnomAD
rs145238804 CA2965665	261	S>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA357282507 rs150020326	266	P>A		No	ClinGen ESP ExAC TOPMed gnomAD
CA2965664 rs150020326	266	P>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA99767164 rs1037396449	272	P>R		No	ClinGen TOPMed
rs1578386513 CA357282460	273	V>A		No	ClinGen Ensembl
CA2965663 rs778324399	274	S>P		No	ClinGen ExAC gnomAD
CA2965645 rs759079919	276	P>A		No	ClinGen ExAC gnomAD
rs776237062 CA2965644	276	P>L		No	ClinGen ExAC gnomAD
rs374522743 CA2965643	277	R>G		No	ClinGen ESP ExAC gnomAD
rs1325383646 CA357288096	278	V>A		No	ClinGen TOPMed gnomAD
TCGA novel	279	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs948199983 CA99798854	282	P>S		No	ClinGen Ensembl
CA99798838 rs747142573	284	V>I		No	ClinGen Ensembl
CA2965639 rs748613172	288	P>S		No	ClinGen ExAC gnomAD
CA2965638 rs779591427	289	P>S		No	ClinGen ExAC TOPMed gnomAD
rs779591427 CA357287971	289	P>T		No	ClinGen ExAC TOPMed gnomAD
CA2965637 rs377618193	290	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA2965635 rs780308739	291	V>A		No	ClinGen ExAC gnomAD
rs749427347 CA2965636	291	V>M		No	ClinGen ExAC gnomAD
rs1186086259 CA357287943	292	R>C		No	ClinGen TOPMed
rs1186086259 CA357287947	292	R>S		No	ClinGen TOPMed
rs1222103553 CA357287900	295	R>Q		No	ClinGen gnomAD
rs756357623 CA2965634	296	P>L		No	ClinGen ExAC gnomAD
CA357287783 rs1405958068	303	P>L		No	ClinGen TOPMed
rs1286422013 CA357287792	303	P>S		No	ClinGen gnomAD
rs763739135 CA2965632	305	R>G		No	ClinGen ExAC gnomAD
rs1286726864 CA357287737	307	P>S		No	ClinGen gnomAD
rs758213446 CA2965631	309	P>S		No	ClinGen ExAC TOPMed gnomAD
CA357287440 rs1168439495	311	R>G		No	ClinGen TOPMed
CA357287416 rs1318035345	314	M>T		No	ClinGen gnomAD
rs1390830794 CA357287397	316	Q>H		No	ClinGen Ensembl
CA99797164 rs1052069846	319	S>C		No	ClinGen TOPMed
CA2965606 rs141113434	319	S>P		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	322	R>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA357287356 rs1295646787	322	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs750010389 CA2965605	323	R>K		No	ClinGen ExAC TOPMed gnomAD
CA2965603 rs200985641	324	I>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs774921055 CA357287331	326	R>H		No	ClinGen ExAC gnomAD
rs774921055 CA2965602	326	R>P		No	ClinGen ExAC gnomAD
CA357287328 rs1299043378	327	Y>H		No	ClinGen TOPMed
CA2965601 rs769146521	329	D>V		No	ClinGen ExAC gnomAD
TCGA novel	341	D>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	349	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1439916523 CA357287094	357	V>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs759522980 CA2965579	365	K>R		No	ClinGen ExAC gnomAD
CA99796599 rs972243668	366	G>D		No	ClinGen Ensembl
CA357286970 rs1462272923	375	G>V		No	ClinGen gnomAD
TCGA novel	379	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA357286921 rs1211466858	382	S>C		No	ClinGen gnomAD
CA357286924 rs1180946886	382	S>P		No	ClinGen TOPMed
rs771005726 CA2965577	383	E>G		No	ClinGen ExAC gnomAD
TCGA novel	386	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1377914761 CA357286888	387	R>I		No	ClinGen gnomAD
CA2965574 rs768404733	392	K>R		No	ClinGen ExAC gnomAD
CA2965554 rs775286366	394	I>M		No	ClinGen ExAC gnomAD
rs749029538 CA2965555	394	I>V		No	ClinGen ExAC
rs769489164 CA2965553	395	M>I		No	ClinGen ExAC gnomAD
rs1389351823 CA357286824	395	M>T		No	ClinGen TOPMed
rs1314182191 CA357286807	398	G>R		No	ClinGen TOPMed
TCGA novel	409	T>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	409	T>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA99795984 rs1036359646	417	T>I		No	ClinGen Ensembl
CA2965548 rs376307166	420	G>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs541924504 CA99795932	421	G>A		No	ClinGen Ensembl
CA2965546 rs752285044	421	G>S		No	ClinGen ExAC gnomAD
rs1319713054 CA357286574 COSM141085	424	R>C	upper_aerodigestive_tract Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA TOPMed
CA357286569 rs1199084313	424	R>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA357286558 rs1196493640	425	R>K		No	ClinGen gnomAD
CA357286508 rs1488930461	429	R>C		No	ClinGen TOPMed gnomAD
rs754378203 CA2965543	430	N>S		No	ClinGen ExAC gnomAD
rs766826220 CA2965542	432	R>Q		No	ClinGen ExAC gnomAD
VAR_036128	434	P>L	a breast cancer sample; somatic mutation [UniProt]	No	UniProt
rs1049233709 COSM351065 CA99795906	435	G>C	lung [Cosmic]	No	ClinGen cosmic curated Ensembl
rs767492113 CA2965539	437	P>L		No	ClinGen ExAC gnomAD
rs1256877178 CA357286403	438	R>C		No	ClinGen TOPMed
rs1474957884 CA357286388	440	I>F		No	ClinGen TOPMed
rs762154155 CA2965538	440	I>T		No	ClinGen ExAC gnomAD
rs1170868574 CA357285990	441	V>A		No	ClinGen gnomAD
CA357285998 rs1391541487	441	V>M		No	ClinGen gnomAD
CA357285970 rs1163380101	442	G>V		No	ClinGen TOPMed
CA99795887 rs774416213	444	G>E		No	ClinGen ExAC TOPMed gnomAD
CA2965537 rs774416213	444	G>V		No	ClinGen ExAC TOPMed gnomAD
COSM40122 CA2965536 rs769670910	446	M>I	large_intestine central_nervous_system [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
CA99795875 rs927583458	447	R>G		No	ClinGen TOPMed
rs1301061476 CA357285915	447	R>H		No	ClinGen gnomAD
TCGA novel	449	R>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA357285906 rs1353143158	449	R>S		No	ClinGen TOPMed
CA2965535 rs745619343	452	R>K		No	ClinGen ExAC gnomAD
rs1390937060 CA357285863	455	P>L		No	ClinGen gnomAD
rs776731334 CA357285862	456	P>A		No	ClinGen ExAC TOPMed gnomAD
rs776731334 CA2965534	456	P>S		No	ClinGen ExAC TOPMed gnomAD
rs372322395 CA2965532	459	G>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA2965531 rs368804327	460	M>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs777490092 CA2965530	462	Q>*		No	ClinGen ExAC TOPMed gnomAD
CA2965527 rs778395439	468	R>K		No	ClinGen ExAC TOPMed gnomAD
rs1271955433 CA357285768	470	T>I		No	ClinGen TOPMed
CA357285765 rs1260042079	471	G>R		No	ClinGen gnomAD
CA2965525 rs529840020	472	Q>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	473	M>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs780546429 CA2965524	473	M>T		No	ClinGen ExAC gnomAD
rs1297137117 CA357285752	473	M>V		No	ClinGen Ensembl
rs1235059529 CA357285738	475	G>S		No	ClinGen gnomAD
rs756683205 CA2965523	476	R>C		No	ClinGen ExAC gnomAD
rs993645902 CA99795842	476	R>H		No	ClinGen TOPMed gnomAD
CA357285701 rs1389288348	480	Q>H		No	ClinGen TOPMed gnomAD
rs917621941 CA99795836	481	R>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA99795837 rs77926705	481	R>S		No	ClinGen Ensembl
rs767685659 COSM177483 CA2965521	482	R>H	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD

No associated diseases with Q9UN86

4 regional properties for Q9UN86

Type	Name	Position	InterPro Accession
domain	RNA recognition motif domain	331 - 409	IPR000504
domain	Nuclear transport factor 2 domain	11 - 133	IPR002075
domain	Nuclear transport factor 2, eukaryote	7 - 135	IPR018222
domain	G3BP2, RNA recognition motif	326 - 408	IPR034376

Functions

		Description
EC Number
Subcellular Localization	Cytoplasm Cytoplasm, Stress granule
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

4 GO annotations of cellular component

Name	Definition
cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytoplasmic stress granule	A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
ribonucleoprotein complex	A macromolecular complex that contains both RNA and protein molecules.

3 GO annotations of molecular function

Name	Definition
mRNA binding	Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
RNA binding	Binding to an RNA molecule or a portion thereof.
signaling receptor complex adaptor activity	The binding activity of a molecule that provides a physical support for the assembly of a multiprotein receptor signaling complex.

7 GO annotations of biological process

Name	Definition
cytoplasmic sequestering of NF-kappaB	The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus.
innate immune response	Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
mRNA transport	The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
positive regulation of stress granule assembly	Any process that starts or increases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.
protein homooligomerization	The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
Ras protein signal transduction	The series of molecular signals within the cell that are mediated by a member of the Ras superfamily of proteins switching to a GTP-bound active state.
stress granule assembly	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.

1 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P97379	G3bp2	Ras GTPase-activating protein-binding protein 2	Mus musculus (Mouse)	PR

10	20	30	40	50	60
MVMEKPSPLL	VGREFVRQYY	TLLNKAPEYL	HRFYGRNSSY	VHGGVDASGK	PQEAVYGQND
70	80	90	100	110	120
IHHKVLSLNF	SECHTKIRHV	DAHATLSDGV	VVQVMGLLSN	SGQPERKFMQ	TFVLAPEGSV
130	140	150	160	170	180
PNKFYVHNDM	FRYEDEVFGD	SEPELDEESE	DEVEEEQEER	QPSPEPVQEN	ANSGYYEAHP
190	200	210	220	230	240
VTNGIEEPLE	ESSHEPEPEP	ESETKTEELK	PQVEEKNLEE	LEEKSTTPPP	AEPVSLPQEP
250	260	270	280	290	300
PKAFSWASVT	SKNLPPSGTV	SSSGIPPHVK	APVSQPRVEA	KPEVQSQPPR	VREQRPRERP
310	320	330	340	350	360
GFPPRGPRPG	RGDMEQNDSD	NRRIIRYPDS	HQLFVGNLPH	DIDENELKEF	FMSFGNVVEL
370	380	390	400	410	420
RINTKGVGGK	LPNFGFVVFD	DSEPVQRILI	AKPIMFRGEV	RLNVEEKKTR	AARERETRGG
430	440	450	460	470	480
GDDRRDIRRN	DRGPGGPRGI	VGGGMMRDRD	GRGPPPRGGM	AQKLGSGRGT	GQMEGRFTGQ

RR