AiPD: Autoinhibited Protein Database

Q9UMY1

Gene name	NOL7 (C6orf90, NOP27)
Protein name	Nucleolar protein 7
Names	Nucleolar protein of 27 kDa
Species	Homo sapiens (Human)
KEGG Pathway	hsa:51406
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

33-208 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

33-208 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

4 structures for Q9UMY1

Entry ID	Method	Resolution	Chain	Position	Source
7MQ8	EM	360 A	ND	1-257	PDB
7MQ9	EM	387 A	ND	1-257	PDB
7MQA	EM	270 A	ND	1-257	PDB
AF-Q9UMY1-F1	Predicted				AlphaFoldDB

241 variants for Q9UMY1

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
CA3640694 rs201177610 CA362778902	3	Q>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC TOPMed gnomAD NCI-TCGA
rs1044328201 CA134827865	4	L>P		No	ClinGen Ensembl
rs1488809193 CA362778947	5	R>L		No	ClinGen gnomAD
CA362778950 rs994713089	6	P>A		No	ClinGen TOPMed gnomAD
CA3640695 rs770549608	6	P>L		No	ClinGen ExAC TOPMed gnomAD
CA362778954 rs770549608	6	P>Q		No	ClinGen ExAC TOPMed gnomAD
CA362778956 rs770549608	6	P>R		No	ClinGen ExAC TOPMed gnomAD
CA362778952 rs994713089	6	P>S		No	ClinGen TOPMed gnomAD
CA134827909 rs994713089	6	P>T		No	ClinGen TOPMed gnomAD
CA134827925 rs1026394258	7	R>*		No	ClinGen TOPMed gnomAD
CA362778963 rs1026394258	7	R>G		No	ClinGen TOPMed gnomAD
CA362778968 rs886550846	7	R>L		No	ClinGen TOPMed gnomAD
rs886550846 CA134827929	7	R>P		No	ClinGen TOPMed gnomAD
rs886550846 CA362778965	7	R>Q		No	ClinGen TOPMed gnomAD
CA3640698 rs767023705	8	A>E		No	ClinGen ExAC TOPMed gnomAD
CA3640697 rs767023705	8	A>G		No	ClinGen ExAC TOPMed gnomAD
CA362778996 rs767023705	8	A>V		No	ClinGen ExAC TOPMed gnomAD
rs775412864 CA362779006	9	S>A		No	ClinGen ExAC TOPMed gnomAD
CA362779012 rs1457923211	9	S>F		No	ClinGen gnomAD
rs775412864 CA3640699	9	S>P		No	ClinGen ExAC TOPMed gnomAD
CA3640700 rs762794506	10	R>H		No	ClinGen ExAC TOPMed gnomAD
rs1297149653 CA362779016	10	R>S		No	ClinGen gnomAD
CA362779044 rs1355156743	12	P>L		No	ClinGen TOPMed gnomAD
CA362779043 rs1355156743	12	P>R		No	ClinGen TOPMed gnomAD
rs1289361298 CA362779035	12	P>S		No	ClinGen gnomAD
rs1289361298 CA362779037	12	P>T		No	ClinGen gnomAD
CA134827976 rs768750065	13	A>S		No	ClinGen ExAC TOPMed gnomAD
rs768750065 CA3640701	13	A>T		No	ClinGen ExAC TOPMed gnomAD
rs1022508478 CA134827982	13	A>V		No	ClinGen gnomAD
CA362779069 rs1203885248	14	S>L		No	ClinGen gnomAD
rs1481739173 CA362779076	15	A>E		No	ClinGen TOPMed gnomAD
rs1162944957 CA362779073	15	A>T		No	ClinGen TOPMed
CA362779078 rs1481739173	15	A>V		No	ClinGen TOPMed gnomAD
CA362779087 rs1475273992	16	E>G		No	ClinGen TOPMed
CA362779099 rs1185574516	17	A>E		No	ClinGen gnomAD
CA362779095 rs1474721508	17	A>T		No	ClinGen gnomAD
rs1218545809 CA362779109	18	M>V		No	ClinGen TOPMed
CA134827988 rs576016625	19	V>G		No	ClinGen 1000Genomes
rs1169125343 CA362779132	20	D>G		No	ClinGen gnomAD
CA362779129 rs1405918554	20	D>N		No	ClinGen gnomAD
CA362779142 rs1457258929	21	E>Q		No	ClinGen TOPMed gnomAD
CA362779165 rs1352320101	23	Q>*		No	ClinGen gnomAD
rs1463079470 CA362779169	23	Q>H		No	ClinGen gnomAD
CA362779182 rs1584896686	24	L>P		No	ClinGen Ensembl
CA362779232 rs1380491201	28	E>D		No	ClinGen TOPMed gnomAD
rs1295552540 CA362779229	28	E>G		No	ClinGen gnomAD
rs968187122 CA134827999	28	E>K		No	ClinGen TOPMed gnomAD
CA3640704 rs760671762	29	E>D		No	ClinGen ExAC gnomAD
CA362779238 rs1361003048	29	E>K		No	ClinGen TOPMed
rs993951658 CA134828005	30	E>A		No	ClinGen TOPMed
TCGA novel	30	E>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1205968388 CA362779272	31	A>G		No	ClinGen gnomAD
rs1484840188 CA362779292	33	H>Y		No	ClinGen gnomAD
rs1208417988 CA362779318	34	G>E		No	ClinGen TOPMed gnomAD
rs1351728705 CA362779347	37	L>I		No	ClinGen TOPMed
CA362779361 rs1417300610	38	G>R		No	ClinGen gnomAD
rs1420512904 CA362779372	39	Q>*		No	ClinGen TOPMed
CA362779407 rs1168699257	42	S>R		No	ClinGen gnomAD
CA362779431 rs1394079601	43	G>D		No	ClinGen gnomAD
CA134828064 rs1007099608	44	A>T		No	ClinGen TOPMed gnomAD
rs1294465328 CA362779440	44	A>V		No	ClinGen gnomAD
CA362779483 rs1360167896 CA362779485	47	E>D		No	ClinGen gnomAD
CA362779492 rs1584896836	48	P>L		No	ClinGen Ensembl
rs1430482796 CA362779502	49	L>R		No	ClinGen gnomAD
CA134828100 rs956006981	50	E>V		No	ClinGen Ensembl
rs1018202144 CA362779516	51	E>*		No	ClinGen TOPMed gnomAD
CA3640708 rs545142311 COSM4160208	51	E>D	thyroid [Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC gnomAD
rs1364742796 CA362779522	51	E>G		No	ClinGen gnomAD
rs1018202144 CA134828109	51	E>K		No	ClinGen TOPMed gnomAD
CA362779538 rs1302814880	52	D>E		No	ClinGen gnomAD
rs1345984232 CA362779543	53	E>*		No	ClinGen TOPMed gnomAD
rs957490832 CA134828116	55	G>E		No	ClinGen TOPMed gnomAD
rs990063143 CA134828117	56	D>V		No	ClinGen TOPMed gnomAD
rs1273275647 CA362779591	57	D>V		No	ClinGen TOPMed
rs1240233578 CA362779701	62	E>G		No	ClinGen gnomAD
rs754300779 CA3640711	63	A>T		No	ClinGen ExAC TOPMed gnomAD
rs1188609350 CA362779729	63	A>V		No	ClinGen gnomAD
rs1394024144 CA362779765	65	E>A		No	ClinGen gnomAD
CA362779759 rs1394024144	65	E>V		No	ClinGen gnomAD
rs755408516 CA3640712	66	E>K		No	ClinGen ExAC gnomAD
CA134828145 rs868034949	67	L>M		No	ClinGen Ensembl
rs1351423263 CA362779813	68	T>A		No	ClinGen Ensembl
rs1157409370 CA362779820	68	T>I		No	ClinGen gnomAD
CA362779818 rs1157409370	68	T>S		No	ClinGen gnomAD
rs11540715 CA362779837	69	F>C		No	ClinGen gnomAD
rs765783930 CA3640714	69	F>L		No	ClinGen ExAC gnomAD
CA134828161 rs11540715	69	F>S		No	ClinGen gnomAD
rs1296468325 CA362779855	70	A>S		No	ClinGen TOPMed
CA362779865 rs1584896965	71	S>G		No	ClinGen Ensembl
CA3640715 rs753226474	74	A>V		No	ClinGen ExAC TOPMed gnomAD
rs1275618928 CA362779942	75	E>*		No	ClinGen gnomAD
CA134828179 rs991367715	76	A>V		No	ClinGen TOPMed
rs948415593 CA134828197	78	E>K		No	ClinGen TOPMed gnomAD
CA3640717 rs780691592	79	E>D		No	ClinGen ExAC gnomAD
CA362780014 rs1331127283	80	E>K		No	ClinGen TOPMed gnomAD
CA362780025 rs1177775290	81	R>W		No	ClinGen TOPMed
rs745492028 CA3640718	83	V>G		No	ClinGen ExAC TOPMed gnomAD
CA362780050 rs1249045732	84	R>Q		No	ClinGen TOPMed
CA362780066 rs1466701761	85	E>D		No	ClinGen gnomAD
rs1232557604 CA362780057	85	E>K		No	ClinGen gnomAD
TCGA novel	85	E>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs371984716 CA3640722	88	R>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs540079238 CA3640723	88	R>L		No	ClinGen 1000Genomes ExAC gnomAD
CA362780119 rs1164750601	89	R>G		No	ClinGen gnomAD
CA3640750 rs770128633	90	D>H		No	ClinGen ExAC TOPMed gnomAD
CA3640751 rs770128633	90	D>N		No	ClinGen ExAC TOPMed gnomAD
CA362780299 rs1243885782	91	K>N		No	ClinGen TOPMed
rs1474446328 CA362780311	92	T>K		No	ClinGen TOPMed gnomAD
rs1474446328 CA362780313	92	T>M		No	ClinGen TOPMed gnomAD
rs1474446328 CA362780312	92	T>R		No	ClinGen TOPMed gnomAD
rs1391000206 CA362780318	93	L>F		No	ClinGen TOPMed gnomAD
CA3640752 rs143073366	94	L>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA3640754 rs752025456	97	K>N		No	ClinGen ExAC TOPMed gnomAD
CA3640753 rs764711363	97	K>R		No	ClinGen ExAC TOPMed gnomAD
CA3640755 rs760188337	98	R>K		No	ClinGen ExAC gnomAD
rs753481615 CA3640757	102	E>G		No	ClinGen ExAC gnomAD
rs1584897365 TCGA novel CA362780511	106	I>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA Ensembl
CA362780545 rs1225512956	108	Q>P		No	ClinGen gnomAD
CA362780555 rs1425306149	109	K>*		No	ClinGen TOPMed
rs745993107 CA3640787	111	R>T		No	ClinGen ExAC TOPMed gnomAD
CA362780689 rs1584898404	112	K>N		No	ClinGen Ensembl
CA134829213 rs370016680	113	L>V		No	ClinGen ESP TOPMed
rs150690716 CA3640790	115	P>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1389328737 CA362780725	116	D>N		No	ClinGen gnomAD
TCGA novel	117	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs772497148 CA3640794	117	T>P		No	ClinGen ExAC gnomAD
rs776260445 CA3640795	118	I>V		No	ClinGen ExAC TOPMed gnomAD
rs747839400 CA134829246	120	E>G		No	ClinGen Ensembl
rs1306725625 CA362780820	124	T>I		No	ClinGen gnomAD
rs995716706 CA134829249	125	A>V		No	ClinGen Ensembl
rs759067282 CA3640796	126	S>L		No	ClinGen ExAC gnomAD
rs945259082 CA134836098	130	I>M		No	ClinGen TOPMed gnomAD
TCGA novel	131	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs563589049 CA3640838	131	K>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1280597947 CA362781281	132	K>I		No	ClinGen TOPMed
CA3640840 rs750301041	133	S>*		No	ClinGen ExAC TOPMed gnomAD
CA3640839 rs750301041	133	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	136	K>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA3640843 rs371855659	138	K>T		No	ClinGen ESP ExAC TOPMed
TCGA novel	140	V>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA3640844 rs778953813	140	V>L		No	ClinGen ExAC gnomAD
CA362781409 rs759155299	142	L>*		No	ClinGen TOPMed gnomAD
CA362781412 rs1186592806	142	L>F		No	ClinGen TOPMed
rs759155299 CA134836426	142	L>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs1248871558 CA362781433	145	K>R		No	ClinGen gnomAD
rs1192749675 CA362781438	146	N>D		No	ClinGen TOPMed
rs755873110 CA3640873	149	C>*		No	ClinGen ExAC TOPMed gnomAD
rs1046742673 CA362781464	149	C>F		No	ClinGen gnomAD
rs746387374 CA3640874	149	C>G		No	ClinGen ExAC
CA134836442 rs1046742673	149	C>S		No	ClinGen gnomAD
CA134836444 rs781692387	150	E>K		No	ClinGen TOPMed
rs1196736737 CA362781497	154	D>H		No	ClinGen TOPMed
CA362781506 rs1449506663	155	S>P		No	ClinGen gnomAD
CA362781511 rs1273720527	156	K>*		No	ClinGen TOPMed
CA3640878 rs747793701	156	K>R		No	ClinGen ExAC TOPMed gnomAD
CA3640879 rs771749772	158	V>I		No	ClinGen ExAC TOPMed gnomAD
rs771749772 CA3640880	158	V>L		No	ClinGen ExAC TOPMed gnomAD
rs372106357 CA3640881	159	K>E		No	ClinGen ESP ExAC TOPMed gnomAD
CA362781535 rs1160004650	159	K>N		No	ClinGen gnomAD
rs776365553 CA134836495	161	Q>*		No	ClinGen ExAC gnomAD
rs776365553 CA3640883	161	Q>E		No	ClinGen ExAC gnomAD
rs1329742623 CA819406588	161	Q>L*		No	ClinGen TOPMed
rs759536441 CA3640884	161	Q>P		No	ClinGen ExAC TOPMed gnomAD
CA3640885 rs765222106	163	V>L		No	ClinGen ExAC TOPMed gnomAD
rs1392843763 CA362781581	167	S>G		No	ClinGen TOPMed
CA134839260 rs915399267	168	Q>*		No	ClinGen TOPMed
CA362781835 rs1271394992	170	K>R		No	ClinGen TOPMed
CA3640913 rs750837924	171	S>I		No	ClinGen ExAC gnomAD
CA362781883 rs1170653180	172	Y>*		No	ClinGen gnomAD
rs1341817505 CA362781876	172	Y>D		No	ClinGen TOPMed
CA134839326 rs143778341	175	V>I		No	ClinGen ESP ExAC TOPMed
CA3640915 rs143778341	175	V>L		No	ClinGen ESP ExAC TOPMed
rs766861896 CA3640916	178	K>E		No	ClinGen ExAC TOPMed gnomAD
CA362781995 rs1399968605	179	D>G		No	ClinGen gnomAD
CA3640919 COSM1545304 rs146992026	183	R>K	lung [Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC TOPMed gnomAD
rs146992026 CA362782040	183	R>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA362782060 rs1363755615	184	D>E		No	ClinGen gnomAD
rs1054895185 CA134839356	185	S>*		No	ClinGen TOPMed gnomAD
rs777278711 CA3640920	186	R>M		No	ClinGen ExAC TOPMed gnomAD
rs370712203 CA362782091	188	Q>*		No	ClinGen ESP ExAC TOPMed gnomAD
CA3640921 rs370712203	188	Q>E		No	ClinGen ESP ExAC TOPMed gnomAD
CA362782124 rs1562291465	190	A>V		No	ClinGen Ensembl
CA3640922 rs374410374	192	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs780821261 CA3640923	194	I>T		No	ClinGen ExAC gnomAD
CA3640925 rs769503951	195	H>Q		No	ClinGen ExAC TOPMed gnomAD
rs138029598 CA3640924	195	H>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1207112386 CA362782249	199	Y>C		No	ClinGen TOPMed
rs768839852 CA3640928	200	G>R		No	ClinGen ExAC gnomAD
CA134839448 rs186388999	201	P>Q		No	ClinGen 1000Genomes
rs1029545504 CA134839437	201	P>S		No	ClinGen TOPMed gnomAD
rs1323535692 CA362782274	202	G>R		No	ClinGen TOPMed
CA362782290 rs1284676461	203	T>N		No	ClinGen TOPMed
rs1349541983 CA362782306	204	N>K		No	ClinGen TOPMed
CA3640929 rs139715216	204	N>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA362782338 rs1333354894	207	T>A		No	ClinGen TOPMed
rs1392467658 CA362782406	209	N>S		No	ClinGen gnomAD
rs768754075 CA3640951	210	K>R		No	ClinGen ExAC gnomAD
rs1408259402 CA362782484	213	S>F		No	ClinGen TOPMed
CA3640952 rs779111944	213	S>P		No	ClinGen ExAC gnomAD
COSM1311589 rs748208703 CA3640953	214	L>F	Variant assessed as Somatic; 0.0 impact. urinary_tract [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA134839656 rs930738568	216	N>K		No	ClinGen gnomAD
rs376188783 CA3640954	216	N>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA3640955 rs773419308	217	K>R		No	ClinGen ExAC TOPMed gnomAD
CA3640957 rs760821581	218	R>T		No	ClinGen ExAC TOPMed gnomAD
rs1222935841 CA362782580	219	L>S		No	ClinGen gnomAD
rs760009783 CA3640961	222	K>R		No	ClinGen ExAC gnomAD
TCGA novel	223	R>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA362782699 rs1562291620	225	A>D		No	ClinGen Ensembl
rs916237894 CA134839719	225	A>P		No	ClinGen TOPMed
CA362782737 rs1481953109	227	Q>P		No	ClinGen gnomAD
rs1246792902 CA362782743	228	F>L		No	ClinGen TOPMed
rs1449159444 CA362782879	234	G>R		No	ClinGen gnomAD
rs1187468961 CA362783509	235	I>F		No	ClinGen gnomAD
rs1562291787 CA362783520	236	Q>K		No	ClinGen Ensembl
rs544905440	238	K>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
CA362783562 rs1327322709	238	K>T		No	ClinGen TOPMed
CA134840317 rs1031878989	239	Q>K		No	ClinGen Ensembl
rs544905440	239	Q>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
rs771845437 CA134840321	241	A>V		No	ClinGen Ensembl
CA362783641 rs1337839622	242	K>R		No	ClinGen TOPMed
CA134840326 rs756154716	243	R>K		No	ClinGen TOPMed gnomAD
rs757352608 CA3641007	243	R>S		No	ClinGen ExAC
CA134840336 rs955685371	244	F>I		No	ClinGen Ensembl
CA362783682 rs1384233347	244	F>L		No	ClinGen TOPMed
CA3641009 rs781355359	245	K>*		No	ClinGen ExAC
CA3641008 rs781355359	245	K>E		No	ClinGen ExAC
rs770128577 CA3641010	246	R>G		No	ClinGen ExAC gnomAD
rs149682751 CA3641011	246	R>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs769092619 CA3641013	247	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA3641012 rs372102737	247	R>W		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1431832461 CA362783762	249	M>I		No	ClinGen gnomAD
rs375127918 CA134840413	249	M>L		No	ClinGen ESP TOPMed
CA3641014 rs774944427	250	V>L		No	ClinGen ExAC TOPMed gnomAD
rs1217301146 CA362783814	252	K>R		No	ClinGen gnomAD
CA3641018 rs759319676	253	M>I		No	ClinGen ExAC gnomAD
CA3641015 rs201690476	253	M>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA3641017 rs776366110	253	M>T		No	ClinGen ExAC TOPMed gnomAD
CA3641016 rs201690476	253	M>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA134840473 rs969931425	255	T>S		No	ClinGen Ensembl
rs765077361 CA3641020	256	K>N		No	ClinGen ExAC gnomAD
CA362783913 rs1487686619	257	K>T		No	ClinGen gnomAD

No associated diseases with Q9UMY1

1 regional properties for Q9UMY1

Type	Name	Position	InterPro Accession
domain	Nucleolar protein 7, C-terminal	172 - 234	IPR012579

Functions

		Description
EC Number
Subcellular Localization	Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

3 GO annotations of cellular component

Name	Definition
chromosome	A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
mitochondrion	A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
nucleolus	A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

1 GO annotations of molecular function

Name	Definition
RNA binding	Binding to an RNA molecule or a portion thereof.

No GO annotations of biological process

Name	Definition
No GO annotations for biological process

1 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q9D7Z3	Nol7	Nucleolar protein 7	Mus musculus (Mouse)	PR

10	20	30	40	50	60
MVQLRPRASR	APASAEAMVD	EGQLASEEEE	AEHGLLLGQP	SSGAAAEPLE	EDEEGDDEFD
70	80	90	100	110	120
DEAPEELTFA	SAQAEAREEE	RRVRETVRRD	KTLLKEKRKR	REELFIEQKK	RKLLPDTILE
130	140	150	160	170	180
KLTTASQTNI	KKSPGKVKEV	NLQKKNEDCE	KGNDSKKVKV	QKVQSVSQNK	SYLAVRLKDQ
190	200	210	220	230	240
DLRDSRQQAA	QAFIHNSLYG	PGTNRTTVNK	FLSLANKRLP	VKRAAVQFLN	NAWGIQKKQN
250
AKRFKRRWMV	RKMKTKK