Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9D7Z3

Entry ID Method Resolution Chain Position Source
AF-Q9D7Z3-F1 Predicted AlphaFoldDB

18 variants for Q9D7Z3

Variant ID(s) Position Change Description Diseaes Association Provenance
rs213005256 20 D>G No EVA
rs3389208531 32 E>D No EVA
rs3389277388 33 H>Q No EVA
rs3389247954 35 L>V No EVA
rs3389272971 44 A>P No EVA
rs3404289286 49 L>P No EVA
rs3389253263 54 D>E No EVA
rs3389247968 93 K>* No EVA
rs30163437 121 A>T No EVA
rs3389280290 128 K>E No EVA
rs3389253279 135 V>F No EVA
rs3389288845 163 Q>R No EVA
rs3403883022 181 R>W No EVA
rs230340123 226 S>G No EVA
rs258567458 226 S>R No EVA
rs3389277325 228 W>* No EVA
rs3389280289 241 K>I No EVA
rs3389208578 242 R>L No EVA

No associated diseases with Q9D7Z3

1 regional properties for Q9D7Z3

Type Name Position InterPro Accession
domain Nucleolar protein 7, C-terminal 167 - 229 IPR012579

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
chromosome A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9UMY1 NOL7 Nucleolar protein 7 Homo sapiens (Human) PR
10 20 30 40 50 60
MVQLRPRLSR IPAPAEAMVD EDQAASEEEE AEHGLLLAQP SSGAAAEPLD EEEDADDEAP
70 80 90 100 110 120
EELTFASAQA EAREEELRVR ASARRDKTLL KEKRKRREEL FIEQKKRKLL PDAVLEQLTT
130 140 150 160 170 180
ASEADIKKSP ENVKVNLKKK SEQHAKGRNS KKVKVQKVQS VGQIESYMAV RLKDEDLRDS
190 200 210 220 230 240
RQEAAKHFIH SCLYGSDSKR TTVNKFLSLN NKRSPVKKAA AQFLTSTWGA QKQQNAKRFK
250
KRWMAKKMKK KTYK