Q9SYM4

PR
Gene name
TPS1
Protein name
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 1
Names
Trehalose-6-phosphate synthase 1, AtTPS1
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT1G78580
EC number
2.4.1.15: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

828-900 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9SYM4

Entry ID Method Resolution Chain Position Source
AF-Q9SYM4-F1 Predicted AlphaFoldDB

20 variants for Q9SYM4

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_1_29557359_C_T 42 V>I No 1000Genomes
tmp_1_29557352_C_G 44 G>A No 1000Genomes
ENSVATH05169273 51 N>T No 1000Genomes
tmp_1_29557319_A_G 55 L>S No 1000Genomes
ENSVATH00148062 71 A>V No 1000Genomes
ENSVATH00148061 76 A>V No 1000Genomes
tmp_1_29557252_G_T 77 H>Q No 1000Genomes
ENSVATH05169271 78 D>N No 1000Genomes
ENSVATH05169270 78 D>V No 1000Genomes
tmp_1_29555416_G_A 391 A>V No 1000Genomes
ENSVATH00148053 486 G>C No 1000Genomes
tmp_1_29554096_T_C 578 H>R No 1000Genomes
ENSVATH05169242 585 S>L No 1000Genomes
tmp_1_29553854_C_T 627 G>R No 1000Genomes
tmp_1_29553853_C_A 627 G>V No 1000Genomes
tmp_1_29552907_G_T 806 T>N No 1000Genomes
ENSVATH00148045 837 R>P No 1000Genomes
ENSVATH00148045 837 R>Q No 1000Genomes
tmp_1_29552674_C_G 884 G>R No 1000Genomes
tmp_1_29552503_A_G 941 S>P No 1000Genomes

No associated diseases with Q9SYM4

No regional properties for Q9SYM4

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9SYM4

Functions

Description
EC Number 2.4.1.15 Hexosyltransferases
Subcellular Localization
  • Vacuole
  • Secreted, cell wall
  • Cytoplasm
  • Determined in transgenic tobacco plants expressing TPS1
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
vacuole A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.

1 GO annotations of molecular function

Name Definition
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity Catalysis of the reaction: UDP-glucose + D-glucose-6-phosphate = UDP + alpha,alpha-trehalose-6-phosphate.

10 GO annotations of biological process

Name Definition
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
developmental vegetative growth The increase in size or mass of non-reproductive plant parts.
embryo development ending in seed dormancy The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
long-day photoperiodism, flowering A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light that exceeds the critical day length. The critical day length varies between species. Although the term is long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 minus the critical day length.
plant-type cell wall biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellulose and pectin-containing cell wall. An example of this is found in Arabidopsis thaliana.
root development The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.
sugar mediated signaling pathway The process in which a change in the level of a mono- or disaccharide such as glucose, fructose or sucrose triggers the expression of genes controlling metabolic and developmental processes.
trehalose biosynthetic process The chemical reactions and pathways resulting in the formation of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.
trehalose metabolic process The chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.
trehalose metabolism in response to stress The chemical reactions and pathways involving trehalose that occur as a result of a stimulus indicating the organism is under stress.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
F4I1A6 TPPC Probable trehalose-phosphate phosphatase C Arabidopsis thaliana (Mouse-ear cress) PR
Q9SU39 TPPF Probable trehalose-phosphate phosphatase F Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MPGNKYNCSS SHIPLSRTER LLRDRELREK RKSNRARNPN DVAGSSENSE NDLRLEGDSS
70 80 90 100 110 120
RQYVEQYLEG AAAAMAHDDA CERQEVRPYN RQRLLVVANR LPVSAVRRGE DSWSLEISAG
130 140 150 160 170 180
GLVSALLGVK EFEARWIGWA GVNVPDEVGQ KALSKALAEK RCIPVFLDEE IVHQYYNGYC
190 200 210 220 230 240
NNILWPLFHY LGLPQEDRLA TTRSFQSQFA AYKKANQMFA DVVNEHYEEG DVVWCHDYHL
250 260 270 280 290 300
MFLPKCLKEY NSKMKVGWFL HTPFPSSEIH RTLPSRSELL RSVLAADLVG FHTYDYARHF
310 320 330 340 350 360
VSACTRILGL EGTPEGVEDQ GRLTRVAAFP IGIDSDRFIR ALEVPEVIQH MKELKERFAG
370 380 390 400 410 420
RKVMLGVDRL DMIKGIPQKI LAFEKFLEEN ANWRDKVVLL QIAVPTRTDV PEYQKLTSQV
430 440 450 460 470 480
HEIVGRINGR FGTLTAVPIH HLDRSLDFHA LCALYAVTDV ALVTSLRDGM NLVSYEFVAC
490 500 510 520 530 540
QEAKKGVLIL SEFAGAAQSL GAGAILVNPW NITEVAASIG QALNMTAEER EKRHRHNFHH
550 560 570 580 590 600
VKTHTAQEWA ETFVSELNDT VIEAQLRISK VPPELPQHDA IQRYSKSNNR LLILGFNATL
610 620 630 640 650 660
TEPVDNQGRR GDQIKEMDLN LHPELKGPLK ALCSDPSTTI VVLSGSSRSV LDKNFGEYDM
670 680 690 700 710 720
WLAAENGMFL RLTNGEWMTT MPEHLNMEWV DSVKHVFKYF TERTPRSHFE TRDTSLIWNY
730 740 750 760 770 780
KYADIEFGRL QARDLLQHLW TGPISNASVD VVQGSRSVEV RAVGVTKGAA IDRILGEIVH
790 800 810 820 830 840
SKSMTTPIDY VLCIGHFLGK DEDVYTFFEP ELPSDMPAIA RSRPSSDSGA KSSSGDRRPP
850 860 870 880 890 900
SKSTHNNNKS GSKSSSSSNS NNNNKSSQRS LQSERKSGSN HSLGNSRRPS PEKISWNVLD
910 920 930 940
LKGENYFSCA VGRTRTNARY LLGSPDDVVC FLEKLADTTS SP