F4I1A6

PR
Gene name
TPPC (At1g22210, F16L1.6)
Protein name
Probable trehalose-phosphate phosphatase C
Names
AtTPPC, Trehalose 6-phosphate phosphatase
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT1G22210
EC number
3.1.3.12: Phosphoric monoester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-72 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for F4I1A6

Entry ID Method Resolution Chain Position Source
AF-F4I1A6-F1 Predicted AlphaFoldDB

31 variants for F4I1A6

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH01086879 4 T>K No 1000Genomes
ENSVATH01086880 6 I>V No 1000Genomes
ENSVATH04621788 8 G>R No 1000Genomes
ENSVATH04621789 16 S>F No 1000Genomes
tmp_1_7841572_G_A 19 D>N No 1000Genomes
ENSVATH01086882 25 V>A No 1000Genomes
ENSVATH04621791 26 R>I No 1000Genomes
ENSVATH00037073 34 V>I No 1000Genomes
ENSVATH01086894 60 R>H No 1000Genomes
ENSVATH01086893 60 R>S No 1000Genomes
ENSVATH11776519 92 E>D No 1000Genomes
tmp_1_7842207_G_A 96 V>I No 1000Genomes
ENSVATH04621802 115 D>E No 1000Genomes
tmp_1_7842265_A_G 115 D>G No 1000Genomes
ENSVATH00037075 119 S>G No 1000Genomes
tmp_1_7842562_C_G 153 Q>E No 1000Genomes
ENSVATH04621805 160 P>A No 1000Genomes
ENSVATH11776641 175 S>F No 1000Genomes
tmp_1_7842769_T_A 187 C>S No 1000Genomes
tmp_1_7842979_C_T 201 A>V No 1000Genomes
tmp_1_7843228_C_T 231 S>F No 1000Genomes
tmp_1_7843239_G_A 235 D>N No 1000Genomes
tmp_1_7843252_C_A 239 A>D No 1000Genomes
tmp_1_7843435_G_A 264 R>H No 1000Genomes
tmp_1_7843434_C_A 264 R>S No 1000Genomes
ENSVATH01086915 280 F>L No 1000Genomes
ENSVATH00037078 283 I>V No 1000Genomes
tmp_1_7843604_C_A 287 T>N No 1000Genomes
tmp_1_7843603_A_C 287 T>P No 1000Genomes
ENSVATH04621818 298 Q>R No 1000Genomes
tmp_1_7843798_A_G 317 T>A No 1000Genomes

No associated diseases with F4I1A6

No regional properties for F4I1A6

Type Name Position InterPro Accession
No domain, repeats, and functional sites for F4I1A6

Functions

Description
EC Number 3.1.3.12 Phosphoric monoester hydrolases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
trehalose-phosphatase activity Catalysis of the reaction: trehalose 6-phosphate + H2O = trehalose + phosphate.

1 GO annotations of biological process

Name Definition
trehalose biosynthetic process The chemical reactions and pathways resulting in the formation of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9SYM4 TPS1 Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SU39 TPPF Probable trehalose-phosphate phosphatase F Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MKITDISGKI ETLVDSLRDM SPTRVRSSFS DEHVSENDDE RSSWIALHPS ALDMFEQIMR
70 80 90 100 110 120
DAEGKQIIMF LDYDGTLSLI TEDHDRAYIT DEMREVVKEV ATYFKTAIIS GRSTDKVQSF
130 140 150 160 170 180
VKLTGIHYAG SHGMDIKGPT NTDQSNQEEV MFQPASDYLP MIDEVVNVLK EKTKSIPGAT
190 200 210 220 230 240
VEHNKFCLTV HFRRVDETGW AALAEQVRLV LIDYPKLRLT QGRKVLELRP SIKWDKGKAL
250 260 270 280 290 300
EFLLNSLGIA ESKDVLPVYI GDDRTDEDAF KVLCERGQGF GIIVSKTIKE TYASYSLQDP
310
SQVKEFLERL VKWKKQTLGE