Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9SW63

Entry ID Method Resolution Chain Position Source
AF-Q9SW63-F1 Predicted AlphaFoldDB

17 variants for Q9SW63

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_4_17389067_T_A 18 V>D No 1000Genomes
ENSVATH14349128 21 V>A No 1000Genomes
ENSVATH14349129 22 A>E No 1000Genomes
tmp_4_17389078_G_C 22 A>P No 1000Genomes
tmp_4_17389100_C_T 29 P>L No 1000Genomes
ENSVATH14349133 79 P>H No 1000Genomes
tmp_4_17389285_G_A 91 G>R No 1000Genomes
tmp_4_17389294_G_T 94 V>L No 1000Genomes
ENSVATH12446221 106 G>E No 1000Genomes
ENSVATH02968134 133 G>V No 1000Genomes
tmp_4_17389427_A_T 138 H>L No 1000Genomes
ENSVATH02968135 152 D>N No 1000Genomes
tmp_4_17389493_A_T 160 N>I No 1000Genomes
tmp_4_17389511_G_T 166 C>F No 1000Genomes
ENSVATH14349134 167 S>N No 1000Genomes
ENSVATH02968136 179 L>F No 1000Genomes
tmp_4_17389594_G_A 194 D>N No 1000Genomes

No associated diseases with Q9SW63

1 regional properties for Q9SW63

Type Name Position InterPro Accession
domain AP2/ERF domain 29 - 92 IPR001471

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
transcription cis-regulatory region binding Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.

3 GO annotations of biological process

Name Definition
ethylene-activated signaling pathway The series of molecular signals generated by the reception of ethylene (ethene, C2H4) by a receptor and ending with modulation of a cellular process, e.g. transcription.
negative regulation of DNA-templated transcription Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
positive regulation of leaf senescence Any process that activates or increases the frequency, rate or extent of leaf senescence.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O22174 ERF008 Ethylene-responsive transcription factor ERF008 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FH94 ERF010 Ethylene-responsive transcription factor ERF010 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SNE1 ERF011 Ethylene-responsive transcription factor ERF011 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
METATEVATV VSTPAVTVAA VATRKRDKPY KGIRMRKWGK WVAEIREPNK RSRIWLGSYS
70 80 90 100 110 120
TPEAAARAYD TAVFYLRGPS ARLNFPELLA GVTVTGGGGG GVNGGGDMSA AYIRRKAAEV
130 140 150 160 170 180
GAQVDALEAA GAGGNRHHHH HQHQRGNHDY VDNHSDYRIN DDLMECSSKE GFKRCNGSLE
190
RVDLNKLPDP ETSDDD