Q9STW8
Gene name |
KOR3 (At4g24260, T22A6.90) |
Protein name |
Endoglucanase 21 |
Names |
Endo-1,4-beta glucanase 21 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT4G24260 |
EC number |
3.2.1.4: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9STW8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9STW8-F1 | Predicted | AlphaFoldDB |
52 variants for Q9STW8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH02919060 | 9 | G>V | No | 1000Genomes | |
| tmp_4_12580091_C_G | 15 | A>P | No | 1000Genomes | |
| ENSVATH00534954 | 34 | A>V | No | 1000Genomes | |
| tmp_4_12580018_G_C | 39 | P>R | No | 1000Genomes | |
| ENSVATH00534953 | 60 | V>A | No | 1000Genomes | |
| ENSVATH14291089 | 62 | L>I | No | 1000Genomes | |
| ENSVATH06766214 | 82 | T>S | No | 1000Genomes | |
| ENSVATH14291088 | 97 | P>L | No | 1000Genomes | |
| tmp_4_12579818_G_T | 106 | P>T | No | 1000Genomes | |
| tmp_4_12579805_G_C | 110 | T>S | No | 1000Genomes | |
| ENSVATH02919059 | 112 | A>S | No | 1000Genomes | |
| tmp_4_12579797_G_T | 113 | L>I | No | 1000Genomes | |
| tmp_4_12579790_G_A | 115 | T>I | No | 1000Genomes | |
| ENSVATH06766212 | 149 | D>N | No | 1000Genomes | |
| tmp_4_12579589_A_T | 156 | D>E | No | 1000Genomes | |
| tmp_4_12579517_C_T | 180 | M>I | No | 1000Genomes | |
| tmp_4_12579244_T_A | 246 | Y>F | No | 1000Genomes | |
| ENSVATH06766209 | 257 | K>R | No | 1000Genomes | |
| ENSVATH06766208 | 287 | D>E | No | 1000Genomes | |
| tmp_4_12579101_T_C | 294 | N>D | No | 1000Genomes | |
| tmp_4_12579082_T_G | 300 | K>T | No | 1000Genomes | |
| tmp_4_12579058_G_T | 308 | T>N | No | 1000Genomes | |
| ENSVATH06766207 | 311 | N>K | No | 1000Genomes | |
| ENSVATH02919056 | 327 | S>T | No | 1000Genomes | |
| ENSVATH06766205 | 364 | A>V | No | 1000Genomes | |
| ENSVATH12195805 | 369 | P>S | No | 1000Genomes | |
| tmp_4_12578870_A_C | 371 | Y>D | No | 1000Genomes | |
| tmp_4_12578844_C_G | 379 | K>N | No | 1000Genomes | |
| ENSVATH06766202 | 397 | G>E | No | 1000Genomes | |
| ENSVATH00534950 | 405 | S>T | No | 1000Genomes | |
| tmp_4_12578655_C_A | 414 | V>F | No | 1000Genomes | |
| ENSVATH06766201 | 421 | Y>F | No | 1000Genomes | |
| ENSVATH06766201 | 421 | Y>S | No | 1000Genomes | |
| ENSVATH00534948 | 437 | H>Y | No | 1000Genomes | |
| tmp_4_12578458_C_A | 453 | A>S | No | 1000Genomes | |
| tmp_4_12578373_C_T | 481 | R>H | No | 1000Genomes | |
| ENSVATH00534947 | 482 | N>D | No | 1000Genomes | |
| ENSVATH06766199 | 485 | R>K | No | 1000Genomes | |
| tmp_4_12578237_C_T | 499 | M>I | No | 1000Genomes | |
| tmp_4_12578232_T_A | 501 | Y>F | No | 1000Genomes | |
| tmp_4_12578227_C_T | 503 | V>M | No | 1000Genomes | |
| ENSVATH00534946 | 522 | K>E | No | 1000Genomes | |
| tmp_4_12578126_C_A | 536 | K>N | No | 1000Genomes | |
| tmp_4_12578125_T_G | 537 | S>R | No | 1000Genomes | |
| ENSVATH06766198 | 573 | L>Q | No | 1000Genomes | |
| tmp_4_12577974_G_A | 587 | S>L | No | 1000Genomes | |
| tmp_4_12577969_C_T | 589 | E>K | No | 1000Genomes | |
| ENSVATH06766197 | 594 | G>S | No | 1000Genomes | |
| tmp_4_12577938_G_A | 599 | T>I | No | 1000Genomes | |
| tmp_4_12577921_G_A | 605 | P>S | No | 1000Genomes | |
| tmp_4_12577907_C_T | 609 | M>I | No | 1000Genomes | |
| tmp_4_12577902_G_T | 611 | T>K | No | 1000Genomes |
No associated diseases with Q9STW8
Functions
| Description | ||
|---|---|---|
| EC Number | 3.2.1.4 | Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| cellulase activity | Catalysis of the endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| cell wall organization | A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. |
| cellulose catabolic process | The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation. |
| response to nematode | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a nematode. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| O80497 | At2g44570 | Endoglucanase 15 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MYGRDPWGGP | LEINAADSMT | DDDRSRNLQD | LDRATPSRPL | DETQQSWLLG | PKVLKKKKYV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DLGCILVSRK | IFLWTLGTIV | VTALLSGFIT | LIVKTLPHHH | HKEPPPDNYT | IALRTALKFF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NAQQSGKLPK | NIYNVSWRHD | SCLQDGKGDP | GQCYKDLVGG | YYDAGDSIKF | NFPMSYAMTM |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LSWSVIEYSA | KYQAAGELEH | VKELIKWGTD | YFLKTFNSSA | DNIYVMVEQV | GSGVSGRGSE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LHNDHYCWMR | PEDIHYKRTV | SQCYSSCSDL | AAEMAAALAS | ASIVFKDNRL | YSKNLVHGAK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TLYRFATTSR | NRYSQNGKES | SKFYNSSMFE | DELLWGGAWL | YYATGNVTYL | ERVTSHHMAE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KAGAFGNSPY | YGVFSWDNKL | PGAQLLLTRM | RLFLSPGYPY | EDMLSEFHNQ | TGRVMCSYLP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| YYKKFNRTNG | GLIQLNHGAP | QPLQYVANAA | FLAALFSDYL | EAADTPGWYC | GPNFYTTEFL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| RNFSRSQIDY | ILGKNPRKMS | YVVGYGQRYP | KQVHHRGASI | PKNMKETCTG | GFKWKKSKKN |
| 550 | 560 | 570 | 580 | 590 | 600 |
| NPNAINGAMV | AGPDKHDGFH | DIRTNYNYTE | PTLAGNAGLV | AALVALSGEK | AVGGIDKNTM |
| 610 | |||||
| FSAVPPLVMA | TPPPPAPWTP |