O80497
Gene name |
At2g44570 (F16B22.6) |
Protein name |
Endoglucanase 15 |
Names |
Endo-1,4-beta glucanase 15 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G44570 |
EC number |
3.2.1.4: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O80497
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O80497-F1 | Predicted | AlphaFoldDB |
54 variants for O80497
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH01987995 | 4 | I>L | No | 1000Genomes | |
| tmp_2_18396255_G_A | 5 | S>L | No | 1000Genomes | |
| tmp_2_18396256_A_G | 5 | S>P | No | 1000Genomes | |
| ENSVATH14615012 | 35 | G>R | No | 1000Genomes | |
| ENSVATH01987993 | 39 | T>M | No | 1000Genomes | |
| ENSVATH05716705 | 41 | S>N | No | 1000Genomes | |
| ENSVATH14615011 | 55 | L>F | No | 1000Genomes | |
| ENSVATH01987990 | 55 | L>S | No | 1000Genomes | |
| ENSVATH01987989 | 56 | D>N | No | 1000Genomes | |
| tmp_2_18396096_C_T | 58 | R>K | No | 1000Genomes | |
| ENSVATH01987988 | 60 | I>K | No | 1000Genomes | |
| ENSVATH01987988 | 60 | I>T | No | 1000Genomes | |
| ENSVATH13638084 | 67 | L>F | No | 1000Genomes | |
| tmp_2_18396066_C_T | 68 | R>K | No | 1000Genomes | |
| tmp_2_18396064_C_T | 69 | D>N | No | 1000Genomes | |
| tmp_2_18396057_G_A | 71 | S>F | No | 1000Genomes | |
| ENSVATH05716697 | 78 | T>S | No | 1000Genomes | |
| tmp_2_18395928_T_A | 82 | Y>F | No | 1000Genomes | |
| tmp_2_18395892_A_G | 94 | L>S | No | 1000Genomes | |
| tmp_2_18395878_T_C | 99 | T>A | No | 1000Genomes | |
| ENSVATH13638077 | 106 | V>I | No | 1000Genomes | |
| ENSVATH05716695 | 123 | A>E | No | 1000Genomes | |
| tmp_2_18395806_C_T | 123 | A>T | No | 1000Genomes | |
| ENSVATH05716694 | 126 | R>K | No | 1000Genomes | |
| tmp_2_18395769_G_A | 135 | A>V | No | 1000Genomes | |
| tmp_2_18395767_G_T | 136 | H>N | No | 1000Genomes | |
| ENSVATH05716692 | 141 | V>F | No | 1000Genomes | |
| ENSVATH13638075 | 177 | G>S | No | 1000Genomes | |
| tmp_2_18395586_G_A,C | 196 | A>G | No | 1000Genomes | |
| tmp_2_18395586_G_A,C | 196 | A>V | No | 1000Genomes | |
| ENSVATH05716689 | 197 | P>L | No | 1000Genomes | |
| tmp_2_18395572_C_G | 201 | A>P | No | 1000Genomes | |
| ENSVATH13638072 | 286 | A>T | No | 1000Genomes | |
| ENSVATH05716685 | 288 | V>I | No | 1000Genomes | |
| ENSVATH01987982 | 293 | L>I | No | 1000Genomes | |
| tmp_2_18395216_C_A | 294 | V>L | No | 1000Genomes | |
| tmp_2_18395197_T_G | 300 | K>T | No | 1000Genomes | |
| tmp_2_18395182_A_G | 305 | M>T | No | 1000Genomes | |
| tmp_2_18395161_G_A | 312 | A>V | No | 1000Genomes | |
| tmp_2_18395121_G_T | 325 | N>K | No | 1000Genomes | |
| ENSVATH05716684 | 326 | N>D | No | 1000Genomes | |
| ENSVATH14615009 | 328 | K>T | No | 1000Genomes | |
| ENSVATH13638070 | 329 | K>N | No | 1000Genomes | |
| tmp_2_18395041_G_A | 352 | A>V | No | 1000Genomes | |
| ENSVATH05716683 | 354 | A>S | No | 1000Genomes | |
| ENSVATH05716682 | 363 | A>S | No | 1000Genomes | |
| tmp_2_18394976_C_G | 374 | V>L | No | 1000Genomes | |
| ENSVATH14615008 | 377 | A>S | No | 1000Genomes | |
| tmp_2_18394675_G_A | 410 | P>L | No | 1000Genomes | |
| ENSVATH01987979 | 429 | P>L | No | 1000Genomes | |
| tmp_2_18394597_A_T | 436 | F>Y | No | 1000Genomes | |
| ENSVATH01987978 | 442 | N>K | No | 1000Genomes | |
| ENSVATH05716676 | 449 | L>V | No | 1000Genomes | |
| ENSVATH05716675 | 485 | L>V | No | 1000Genomes |
No associated diseases with O80497
Functions
| Description | ||
|---|---|---|
| EC Number | 3.2.1.4 | Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular region | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| cellulase activity | Catalysis of the endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cell wall organization | A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. |
| cellulose catabolic process | The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9STW8 | KOR3 | Endoglucanase 21 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSCISSQCFI | TIKSICIVLL | LSITCGAVSA | NSNYGEALTK | SLLYFEAQRS | GKLPLDQRVI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| WRGDSALRDG | SDAHVDLTGG | YYDAGDNMKF | GFPLAFTTTM | LAWSSVEMES | QLKAHQEHGN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TLAALRWATD | YLIKAHPEPN | VLYGQVGDAN | LDHACWMRPE | DMTTPRPSYR | IDPQHPGADL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AGETAAAMAA | ASLAFAPSDS | AYAKTLISHA | KELFEFAKDY | PGVYHNSIPN | AGGFYPSSGY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EDELLWAAAW | LHRATGDQTY | LDHLTQASNS | GGARSVFAWD | DKFLGAQVLV | AKLVFEGKVK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NEGKMIEYKS | MAEQFICNCA | QKGFNNVKKT | PGGLLWFLPW | DNLQYTATAS | FALATYAKYL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| EAAQTSIQCP | NGDVLQASDL | LNLARAQVDY | ILGSNPKKMS | YMVGYGTNYP | KRPHHRGASI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VSIKNDPKPV | TCNGGFEAWY | NNPKPNPNLL | VGAIVGGPDE | YDAYGDERSD | FQHGEPDTVT |
| 490 | |||||
| VAPLLGVLAA | IA |