Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9SR06

Entry ID Method Resolution Chain Position Source
AF-Q9SR06-F1 Predicted AlphaFoldDB

13 variants for Q9SR06

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH02112429 14 S>G No 1000Genomes
tmp_3_1272345_T_A 24 K>M No 1000Genomes
ENSVATH10492023 68 P>L No 1000Genomes
tmp_3_1271500_C_T 119 A>T No 1000Genomes
tmp_3_1271488_T_C 123 N>D No 1000Genomes
ENSVATH05771088 192 E>D No 1000Genomes
ENSVATH13869414 207 A>T No 1000Genomes
ENSVATH05771086 211 M>V No 1000Genomes
tmp_3_1270790_C_T 263 D>N No 1000Genomes
tmp_3_1270426_T_C 355 K>R No 1000Genomes
ENSVATH05771079 374 V>I No 1000Genomes
ENSVATH02112398 414 Q>E No 1000Genomes
ENSVATH02112397 414 Q>L No 1000Genomes

No associated diseases with Q9SR06

3 regional properties for Q9SR06

Type Name Position InterPro Accession
domain Pre-mRNA cleavage complex subunit Clp1, C-terminal 330 - 442 IPR010655
domain Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain 137 - 325 IPR032319
domain Clp1, N-terminal beta-sandwich domain 27 - 115 IPR032324

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mRNA cleavage factor complex Any macromolecular complex involved in cleavage or polyadenylation of mRNA molecules.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
polynucleotide 5'-hydroxyl-kinase activity Catalysis of the reaction: NTP + 5'-dephosphopolynucleotide = NDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.

7 GO annotations of biological process

Name Definition
flower development The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem.
mRNA polyadenylation The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
mRNA processing Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
phyllome development The process whose specific outcome is the progression of a phyllome over time, from its formation to the mature structure. A phyllome is a collective term for all the different types of leaves appearing on plants.
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
tRNA splicing, via endonucleolytic cleavage and ligation Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.
vegetative to reproductive phase transition of meristem The process involved in transforming a meristem that produces vegetative structures, such as leaves, into a meristem that produces reproductive structures, such as a flower or an inflorescence.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q08685 CLP1 mRNA cleavage and polyadenylation factor CLP1 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
10 20 30 40 50 60
MAYGGPSMNP PALSGAVPGS ANLKQVKLER ESELRIEVSE EPLRLRVVNG TAEIFGSELP
70 80 90 100 110 120
PEIWRTFPPR MKFAVFTWYG ATIEMDGVTE TDYTADETPM VSYINVHAIL DARRRFAKAS
130 140 150 160 170 180
TSNDPESSQG PRVIVVGPTD SGKSTLTKML LSWAAKQGWR PTFVDLDVGQ GSITIPGSIA
190 200 210 220 230 240
AAPIEMPLDP VEGFPLDMAL VYYYGHASPN MNVELYKALV KELAQVLEKQ FVGNPESRAA
250 260 270 280 290 300
GMVINTMGWI EGIGYELLLH AIDTFNASVV LVLGQEKLFS RLKDVLRSKS NVDVVKLHKS
310 320 330 340 350 360
GGVVARVKEV RKRSRNFKIQ EYFYGLSKEL SPYANTSSFS DLQVFRIGGG PQAPKSALPA
370 380 390 400 410 420
GSTSVSNPLR VTPVNIDDRD LLHSVLAVSY AEEPDQIISS NVSGFVYVTE VNVQKKKITY
430 440
LAPSPGTLPS KLLVAGSLAW LESV