Q9SA65
PR
Gene name |
At1g03050 (F10O3.13) |
Protein name |
Putative clathrin assembly protein At1g03050 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G03050 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9SA65
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9SA65-F1 | Predicted | AlphaFoldDB |
58 variants for Q9SA65
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH04511757 | 10 | I>M | No | 1000Genomes | |
| ENSVATH04511758 | 12 | A>T | No | 1000Genomes | |
| ENSVATH00003594 | 16 | Q>K | No | 1000Genomes | |
| ENSVATH10512028 | 24 | V>F | No | 1000Genomes | |
| ENSVATH04511760 | 50 | E>G | No | 1000Genomes | |
| ENSVATH13850508 | 52 | K>R | No | 1000Genomes | |
| ENSVATH01007943 | 54 | I>F | No | 1000Genomes | |
| tmp_1_707913_A_C | 63 | Y>S | No | 1000Genomes | |
| ENSVATH10512029 | 92 | L>V | No | 1000Genomes | |
| tmp_1_708002_A_G | 93 | I>V | No | 1000Genomes | |
| tmp_1_708015_G_A | 97 | R>K | No | 1000Genomes | |
| tmp_1_708063_C_T | 113 | A>V | No | 1000Genomes | |
| tmp_1_708071_C_G | 116 | R>G | No | 1000Genomes | |
| tmp_1_708083_C_T | 120 | L>F | No | 1000Genomes | |
| tmp_1_708133_C_G | 136 | D>E | No | 1000Genomes | |
| ENSVATH04511766 | 167 | C>S | No | 1000Genomes | |
| ENSVATH04511767 | 213 | L>F | No | 1000Genomes | |
| tmp_1_708501_G_A | 221 | R>H | No | 1000Genomes | |
| ENSVATH04511770 | 231 | V>L | No | 1000Genomes | |
| ENSVATH13850510 | 274 | D>Y | No | 1000Genomes | |
| ENSVATH00003597 | 281 | K>N | No | 1000Genomes | |
| ENSVATH04511771 | 352 | E>K | No | 1000Genomes | |
| tmp_1_708996_G_A | 356 | E>K | No | 1000Genomes | |
| tmp_1_709002_G_A | 358 | E>K | No | 1000Genomes | |
| ENSVATH04511772 | 370 | P>L | No | 1000Genomes | |
| ENSVATH01007947 | 375 | D>E | No | 1000Genomes | |
| ENSVATH04511773 | 387 | V>M | No | 1000Genomes | |
| tmp_1_709142_T_A | 404 | N>K | No | 1000Genomes | |
| tmp_1_709140_A_T | 404 | N>Y | No | 1000Genomes | |
| tmp_1_709146_A_C | 406 | N>H | No | 1000Genomes | |
| tmp_1_709152_G_T | 408 | G>C | No | 1000Genomes | |
| ENSVATH13850512 | 423 | D>E | No | 1000Genomes | |
| tmp_1_709208_C_A | 426 | Y>* | No | 1000Genomes | |
| tmp_1_709222_G_A | 431 | G>D | No | 1000Genomes | |
| ENSVATH10512032 | 440 | A>T | No | 1000Genomes | |
| ENSVATH13850513 | 454 | Q>H | No | 1000Genomes | |
| tmp_1_709308_T_A | 460 | S>T | No | 1000Genomes | |
| ENSVATH04511775 | 462 | Q>H | No | 1000Genomes | |
| tmp_1_709315_A_C | 462 | Q>P | No | 1000Genomes | |
| tmp_1_709353_C_T | 475 | L>F | No | 1000Genomes | |
| tmp_1_709368_C_A | 480 | Q>K | No | 1000Genomes | |
| ENSVATH04511777 | 490 | T>I | No | 1000Genomes | |
| ENSVATH04511778 | 494 | Y>C | No | 1000Genomes | |
| ENSVATH04511778 | 494 | Y>S | No | 1000Genomes | |
| ENSVATH00003599 | 499 | S>N | No | 1000Genomes | |
| tmp_1_709443_T_C | 505 | F>L | No | 1000Genomes | |
| ENSVATH13850514 | 513 | A>V | No | 1000Genomes | |
| tmp_1_709619_C_A | 520 | A>E | No | 1000Genomes | |
| ENSVATH04511781 | 522 | S>* | No | 1000Genomes | |
| ENSVATH00003601 | 522 | S>A | No | 1000Genomes | |
| ENSVATH04511782 | 527 | N>I | No | 1000Genomes | |
| ENSVATH00003602 | 528 | A>V | No | 1000Genomes | |
| ENSVATH10512106 | 531 | I>N | No | 1000Genomes | |
| tmp_1_709666_C_A | 536 | P>T | No | 1000Genomes | |
| tmp_1_709684_G_A | 542 | A>T | No | 1000Genomes | |
| tmp_1_709699_G_T | 547 | A>S | No | 1000Genomes | |
| ENSVATH04511783 | 589 | Q>H | No | 1000Genomes | |
| tmp_1_709847_C_T | 596 | T>I | No | 1000Genomes |
No associated diseases with Q9SA65
Functions
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| clathrin-coated pit | A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes. |
| clathrin-coated vesicle | A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| pollen tube | A tubular cell projection that is part of a pollen tube cell and extends from a pollen grain. |
| pollen tube tip | The region at growing end of the pollen tube cell, where polarized growth occurs. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| 1-phosphatidylinositol binding | Binding to a phosphatidylinositol, a glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol. |
| clathrin heavy chain binding | Binding to a clathrin heavy chain. |
| phosphatidylinositol-4,5-bisphosphate binding | Binding to phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions. |
| SNARE binding | Binding to a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| clathrin coat assembly | The process that results in the assembly of clathrin triskelia into the ordered structure known as a clathrin cage. |
| clathrin-dependent endocytosis | An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles. |
| pollen tube growth | Growth of pollen via tip extension of the intine wall. |
| protein localization to plasma membrane | A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane. |
| vesicle budding from membrane | The evagination of a membrane, resulting in formation of a vesicle. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8H0W9 | At5g10410 | Putative clathrin assembly protein At5g10410 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGSSKFKRAI | GAVKDQTSVG | LAKVNGRSAS | LSELDVAIVK | ATRHEEFPAE | EKYIREILSL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TSYSRSYINA | CVSTLSRRLN | KTKCWTVALK | TLILIQRLLG | EGDQAYEQEI | FFATRRGTRL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LNMSDFRDVS | RSNSWDYSAF | VRTYALYLDE | RLDFRMQARH | GKRGVYCVGG | EADEEEQDQA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AADLSTAIVV | RSQPIAEMKT | EQIFIRIQHL | QQLLDRFLAC | RPTGNARNNR | VVIVALYPIV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KESFQIYYDV | TEIMGILIER | FMELDIPDSI | KVYDIFCRVS | KQFEELDQFY | SWCKNMGIAR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SSEYPEIEKI | TQKKLDLMDE | FIRDKSALEH | TKQSKSVKSE | ADEDDDEART | EEVNEEQEDM |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NAIKALPEPP | PKEEDDVKPE | EEAKEEVIIE | KKQEEMGDLL | DLGNTNGGEA | GQAGDSLALA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LFDGPYASGS | GSESGPGWEA | FKDDSADWET | ALVQTATNLS | GQKSELGGGF | DMLLLNGMYQ |
| 490 | 500 | 510 | 520 | 530 | 540 |
| HGAVNAAVKT | STAYGASGSA | SSMAFGSAGR | PAATMLALPA | PSTANGNAGN | INSPVPMDPF |
| 550 | 560 | 570 | 580 | 590 | |
| AASLEVAPPA | YVQMNDMEKK | QRMLMEEQMM | WDQYSRDGRQ | GHMNLRQNQN | QPYSYTPQY |