Q9QZE7
Gene name |
Tsnax (Trax) |
Protein name |
Translin-associated protein X |
Names |
Translin-associated factor X |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:53424 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9QZE7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9QZE7-F1 | Predicted | AlphaFoldDB |
15 variants for Q9QZE7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs48188750 | 5 | E>K | No | EVA | |
| rs579487096 | 35 | V>L | No | EVA | |
| rs864278405 | 62 | D>N | No | EVA | |
| rs3388997084 | 74 | L>H | No | EVA | |
| rs3389014591 | 92 | S>R | No | EVA | |
| rs580640164 | 169 | E>D | No | EVA | |
| rs584074143 | 182 | L>I | No | EVA | |
| rs3388989258 | 195 | T>N | No | EVA | |
| rs3389022897 | 206 | V>M | No | EVA | |
| rs3389025373 | 214 | P>H | No | EVA | |
| rs3389014624 | 218 | S>C | No | EVA | |
| rs3399707016 | 222 | R>C | No | EVA | |
| rs3389013757 | 241 | K>E | No | EVA | |
| rs3388997140 | 266 | E>D | No | EVA | |
| rs3389022840 | 290 | S>A | No | EVA |
No associated diseases with Q9QZE7
No regional properties for Q9QZE7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9QZE7 | |||
Functions
6 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| endoribonuclease complex | A protein complex which is capable of endoribonuclease activity. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| perinuclear region of cytoplasm | Cytoplasm situated near, or occurring around, the nucleus. |
7 GO annotations of molecular function
| Name | Definition |
|---|---|
| A2A adenosine receptor binding | Binding to an A2A adenosine receptor. |
| endoribonuclease activity | Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. |
| metal ion binding | Binding to a metal ion. |
| protein-containing complex binding | Binding to a macromolecular complex. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| sequence-specific DNA binding | Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
| single-stranded DNA binding | Binding to single-stranded DNA. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| cell differentiation | The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. |
| siRNA processing | A process leading to the generation of a functional small interfering RNA (siRNA). Includes the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides. May also include amplification of the siRNA by RNA-directed RNA polymerase. |
| spermatogenesis | The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q99598 | TSNAX | Translin-associated protein X | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNGKEGPGGF | RKRKHDTFPH | NQRREGKDAS | LSSPVMLAFK | SFQQELDARH | DKYERLVKLS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RDITVESKRT | IFLLHRITSA | PDMEEILTES | ESKLDGVRQK | ILQVAQELSG | EDMHQFHRAV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TTGLQEYVEA | VSFQHFIKTR | SLISMEEINK | QLTFTAEDSG | KESKTPPAEG | QEKQLVTWRL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KLTPVDYLLG | VADLTGELMR | MCINSVGNGD | IDTPFEVSQF | LRQVYDGFSF | IGNTGPYEVS |
| 250 | 260 | 270 | 280 | ||
| KKLYTLKQSL | AKVENACYAL | KVRGSEIPKH | MLADVFSVKT | DMIDQEESIS |