Q9QZ09
Gene name |
Phtf1 |
Protein name |
Protein PHTF1 |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:18685 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9QZ09
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9QZ09-F1 | Predicted | AlphaFoldDB |
22 variants for Q9QZ09
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3393424958 | 40 | P>A | No | EVA | |
| rs3388658386 | 48 | P>L | No | EVA | |
| rs3388659269 | 57 | R>T | No | EVA | |
| rs3388651501 | 76 | K>R | No | EVA | |
| rs3388643711 | 89 | S>R | No | EVA | |
| rs3388655868 | 93 | Q>R | No | EVA | |
| rs3388652444 | 100 | F>Y | No | EVA | |
| rs3388651467 | 200 | F>S | No | EVA | |
| rs3388644291 | 226 | S>L | No | EVA | |
| rs3388636144 | 312 | L>F | No | EVA | |
| rs3388652473 | 348 | Q>* | No | EVA | |
| rs3388655575 | 360 | S>R | No | EVA | |
| rs3388644237 | 372 | R>* | No | EVA | |
| rs3388655556 | 374 | D>H | No | EVA | |
| rs3388656417 | 532 | N>K | No | EVA | |
| rs3388651392 | 588 | N>I | No | EVA | |
| rs3388656477 | 670 | K>N | No | EVA | |
| rs3388651377 | 697 | Q>* | No | EVA | |
| rs3388652461 | 700 | L>P | No | EVA | |
| rs3388658338 | 722 | Y>* | No | EVA | |
| rs3388653694 | 724 | L>M | No | EVA | |
| rs3388651460 | 757 | W>L | No | EVA |
No associated diseases with Q9QZ09
1 regional properties for Q9QZ09
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | PHTF1/2, N-terminal | 5 - 150 | IPR021980 |
Functions
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cis-Golgi network | The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum. |
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MASNERDAIS | WYQKKIGAYD | QQIWEKSIEQ | TQIKGFKNKP | KKMGHIKPDL | IDVDLIRGST |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FAKAKPEIPW | TSLTRKGLVR | VVFFPLFSSW | WIQVTSLRIF | VWLLLLYLMQ | VTAVVLYLLM |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PIVSASEVLG | PLCLMLLMGT | VHCQIVSTQI | TRPSGNNGNR | RRRKLRKTVN | GDGSRDNGNN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SPDKVRAVET | LESASSVGGF | WGTLFGNRIK | RVKLVSNKGT | ETDNDSGCFH | PILKKRQGRP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EIRMWQAREK | AKVSDGEKCR | REAYRRLGNG | ISDDLSSEED | GEARTQMILL | RRSVEGASSD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NGYEVKNRRS | ILSRHLNSQV | KKTTRWCHIV | RDSDSLAESE | FESAVFSQGS | RSGMSGGSRS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LNLSRRDSES | TRHDSETEDM | LWDDLLHGPE | CRSSVTSDSE | GAHVNTIHSG | TKRDPKEDVF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| QQNHLFWLQN | SSPASERVSA | IIWEGNECKK | MDMSVLEISG | IIMSRVNAYE | QGVGYQMLGN |
| 490 | 500 | 510 | 520 | 530 | 540 |
| AVTVGLALFP | FLYRLFREKS | FDQLKSISAE | EVLTLFCGAP | PVTPVVILSI | INFIERLCLT |
| 550 | 560 | 570 | 580 | 590 | 600 |
| WMFFFMMCVA | ERTYKQRFLF | AKLFSHITSA | RKARKYEIPH | FRLKKVENIK | IWLSLRSYLK |
| 610 | 620 | 630 | 640 | 650 | 660 |
| RRGPQRSVDV | VVSSVFLLTL | SIAFICCAQV | LQGHKTFLND | AYNWEFLIWE | TALLLFLLRL |
| 670 | 680 | 690 | 700 | 710 | 720 |
| ASLGSETNKK | YSNVSILLTE | QINLYLKMEK | KPNKKEQLTL | VNNVLKLSTK | LLKELDTPFR |
| 730 | 740 | 750 | 760 | ||
| LYGLTMNPLI | YNITRVVILS | AVSGVISDLL | GFNIRLWKIK | S |