Q8CB19

PR
Gene name
Phtf2
Protein name
Protein PHTF2
Names
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:68770
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

259-335 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8CB19

Entry ID Method Resolution Chain Position Source
AF-Q8CB19-F1 Predicted AlphaFoldDB

No variants for Q8CB19

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8CB19

No associated diseases with Q8CB19

1 regional properties for Q8CB19

Type Name Position InterPro Accession
domain PHTF1/2, N-terminal 4 - 153 IPR021980

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8N3S3 PHTF2 Protein PHTF2 Homo sapiens (Human) PR
Q9QZ09 Phtf1 Protein PHTF1 Mus musculus (Mouse) PR
10 20 30 40 50 60
MASRVTDAIV WYQKKIGAYD QQIWEKSVEQ REIKGLRNKP KKTAHVKPDL IDVDLVRGSA
70 80 90 100 110 120
FAKAKPESPW TSLTRKGIVR VVFFPFFSRW WLQVTSRVIF SWLLVLYLLQ VAAIVLFCSA
130 140 150 160 170 180
PSPHSIPLTE VIGPIWLMLL LGTVHCQIVS TRTPKPPLGT GGKRRRKLRK AAHLEVHREG
190 200 210 220 230 240
DGSSTTDNTQ EGAVQSYGAG APYSVGTVFR DLWLAAFFLS GSKKAKNSID KSTETDNGYV
250 260 270 280 290 300
SLDGKRTVKS SEDGAQYHEL QCETVGPEDA AWATRTPRSV PAKDTQRKIT NVSDEVSSEE
310 320 330 340 350 360
GPETGYPLRG HVDRTSESGL RNRKPHHYKK HYANEDAPKS GTSCSSRCSS SRQDSESTRP
370 380 390 400 410 420
ESETEGVLWE DLLHCAECRS SCTSETDVGN PQINPCGKKE YRDDPFHQSH LPWLHSSHPG
430 440 450 460 470 480
LEKISAIVWE GNDCKKADMS VLEISGMIMN RVNNHVPGIG YQVFGNAISL ILGLTPFVFR
490 500 510 520 530 540
LSQATDLEQL TAHSASELYV IAFGSNEDVM VLSMVLISFV VRVSLVWIFF FLLCVAERTY
550 560 570 580 590 600
KQRLLFAKLF GHLTSARRAR KSEVPHFRLK KVQNIKMWLS LRSYLKRRGP QRSVDVIVSS
610 620 630 640 650 660
AFLLTISVVF ICCAQLLHVH EIFLDCHCNW ELVIWCISLT LFLLRFVTLG SETSKKYSNT
670 680 690 700 710 720
SILLTEQINL YLKMEKKPNK KEELTLVNNV LKLATKLLKE LDSPFRLYGL TMNPLLYNIT
730 740
QVVILSAVSG VISDLLGFNL KLWKIKS