Q9PUU8

PR
Gene name
CNMD
Protein name
Leukocyte cell-derived chemotaxin 1
Names
Chondromodulin
Species
Gallus gallus (Chicken)
KEGG Pathway
gga:395600
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-57 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9PUU8

Entry ID Method Resolution Chain Position Source
AF-Q9PUU8-F1 Predicted AlphaFoldDB

No variants for Q9PUU8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9PUU8

No associated diseases with Q9PUU8

1 regional properties for Q9PUU8

Type Name Position InterPro Accession
domain BRICHOS domain 103 - 200 IPR007084

Functions

Description
EC Number
Subcellular Localization
  • [Chondromodulin-1]: Secreted, extracellular space, extracellular matrix
  • Accumulated in the inter-territorial matrix of cartilage
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
endomembrane system A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
cartilage development The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P17404 CNMD Leukocyte cell-derived chemotaxin 1 Bos taurus (Bovine) PR
O75829 CNMD Leukocyte cell-derived chemotaxin 1 Homo sapiens (Human) PR
Q9Z1F6 Cnmd Leukocyte cell-derived chemotaxin 1 Mus musculus (Mouse) PR
P58239 cnmd Leukocyte cell-derived chemotaxin 1 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MAEGSEKVPI ARAGPEDVEQ GLPPAYTAAV PPPGPGRLLK AGATVLIAGA LLLLAGAIGA
70 80 90 100 110 120
FYFWKATERQ VYNVHYTMSI NGKVQDGSME IDAGNNLETF KTGSGSEEAV EVHDFQIGIT
130 140 150 160 170 180
GIRFAGGEKC YIKAQPKARV PEVDAMTKAS LSSDLEDEIM PVRFDENSLI WVAADEPIKH
190 200 210 220 230 240
NGFLSPKILE LCGDLPIFWL RPTYPKDKQR ERREMKRNKR QSESNFDAEH RAAAAEEVNT
250 260 270 280 290 300
RSTPTQLTQD LGPQSNETRP MQQESDQTLN PDNPYNQLEG EGMAFDPMLD HLGVCCIECR
310 320 330 340
RSYTQCQRIC EPLLGYYPWP YNYQGCRTAC RIIMPCSWWV ARIMGVV