Q9NEU2

PR
Gene name
pro-3 (Y39B6A.14)
Protein name
Protein SDA1 homolog
Names
Proximal proliferation in germline protein 3
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_Y39B6A.14
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

571-787 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9NEU2

Entry ID Method Resolution Chain Position Source
AF-Q9NEU2-F1 Predicted AlphaFoldDB

No variants for Q9NEU2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9NEU2

No associated diseases with Q9NEU2

2 regional properties for Q9NEU2

Type Name Position InterPro Accession
domain SDA1, C-terminal domain 456 - 796 IPR007949
domain SDA1, N-terminal 99 - 150 IPR012977

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

5 GO annotations of biological process

Name Definition
cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
gonadal mesoderm development The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
ribosomal large subunit biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis.
ribosomal large subunit export from nucleus The directed movement of a ribosomal large subunit from the nucleus into the cytoplasm.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q7KKH3 Mys45A Protein SDA1 homolog Drosophila melanogaster (Fruit fly) PR
Q6NV26 sdad1 Protein SDA1 homolog Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MGKVSKSPGK GEKRIGKVGK KNGKSNAPTE GSNSGKASRF TMSERNLGLM QEIIRKDPES
70 80 90 100 110 120
YKEEFLEQFN YFVQTMKLLH LQPEQSRQEM QSLVDSVLFL SGLAKHYPKE SKQFSDSLFE
130 140 150 160 170 180
LLREQGAGLD PEVRMAFCKA LVLLRNQDMI DPIILMETFF ELVKVEDKVL RKFLLSSISA
190 200 210 220 230 240
HLKRVYHKKK DVKMLGKIQN LCFSKMKDSR SIVARAAQLV CIDAFRRKFW RDARTANVIA
250 260 270 280 290 300
QACFHKVAKI QVTSMKFFLG SENENGDAED SDEMDSDAED NTKTLKEVMT SFRNVKKTRK
310 320 330 340 350 360
REKNVERAKK MISKKKKAKK EGRSKECNLM AIQSLYDPQE FVDRLFGAVE AKKMDNFEVR
370 380 390 400 410 420
LFKIALCARI IGIHRLHTLS FYSYLHRFLQ PKQRDVTKIL LYAAQACHEM VPPDTVEQLI
430 440 450 460 470 480
RVIANNFVTD RNSPEAMTVG INAIREILSN CPFAATEELL RDLSEYKTYK NKNVSMAARS
490 500 510 520 530 540
LITLFRAVNP KLLARKDRGK PQEKDDEDEE YNGFARPKVH DFISGAEILD EDAADGEQGH
550 560 570 580 590 600
LEEDGTDSEL DVSDVDTDDV DTDDDADEPV AKKKRVEQKS VENDAESDAD DEEIEDEEEM
610 620 630 640 650 660
DDEEEEIEIS DEEEEEIDDE AEEEAVVEEE ASEAVEKDPK LKASKNSMDR IMTQEDFKNI
670 680 690 700 710 720
KAYQLKKQLI GEKRLKKQMG KGRSQADERI VDEMAEKLEL KRSSDGLARL SDIEHFYKKK
730 740 750 760 770 780
RQSKEERMAD VMAGRADEDY KFGRPKKNGA HVGRTNDQNS KKKVFAMVKN KIRGRNRQRS
790 800
FRDQQKSLRH YLMRQSGRKP Q