Q7KKH3

PR
Gene name
Mys45A (CG8070)
Protein name
Protein SDA1 homolog
Names
Mystery protein 45A
Species
Drosophila melanogaster (Fruit fly)
KEGG Pathway
dme:Dmel_CG8070
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

514-591 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7KKH3

Entry ID Method Resolution Chain Position Source
AF-Q7KKH3-F1 Predicted AlphaFoldDB

No variants for Q7KKH3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7KKH3

No associated diseases with Q7KKH3

2 regional properties for Q7KKH3

Type Name Position InterPro Accession
domain SDA1, C-terminal domain 409 - 711 IPR007949
domain SDA1, N-terminal 62 - 113 IPR012977

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
ribosomal large subunit biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis.
ribosomal large subunit export from nucleus The directed movement of a ribosomal large subunit from the nucleus into the cytoplasm.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9NEU2 pro-3 Protein SDA1 homolog Caenorhabditis elegans PR
Q6NV26 sdad1 Protein SDA1 homolog Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MVRPNNNQLP ENLPQLQNLI KRDPESYSDE FHIQYQHFLS LLEVFALNPS EENKSLDDIV
70 80 90 100 110 120
MFVAQVAQCY PAVCEEFPKR LSDLLKNYAT VLDPAMRNCF VKALILLRNK NLVPALDILE
130 140 150 160 170 180
LFFQLLRCPD KNLRTFLQTH IVTDIKNMNA KHKDMKLNSS LQAFMYSMLK DANPKAAKMS
190 200 210 220 230 240
ADIMIELYKK NIWNDSKTVN VIATVGCFSK VTKVLVTSLK FFLGHDEEDE EEDTDSENEV
250 260 270 280 290 300
DLKGALMANR VNKKTKKRTK QLAQIKKQAV KAQKKKKNAP AFNFSGIHLV HNPQGMAEGL
310 320 330 340 350 360
FKQLQATNER FEVKLMHLDV ISRLIGIHDL FLFGFYPYIT RFLQPHQRQV TRVLQFAAQA
370 380 390 400 410 420
SHELVPGDII EPILKTIANN FITERNSSDV MAIGLNATRE ICMRCPLAMG EDLLQDLAMY
430 440 450 460 470 480
KTYKEKSVMM AARSLITLYR EQLPALLHKK DRGRQTEAQA ERKVRAYGER EVHDTVLGAE
490 500 510 520 530 540
ALLKDSKTID IESEDDTDSN DGEWVNVAHS DGEGGGADDD EEDEDEDEDD DDEDEDEENS
550 560 570 580 590 600
NDEENEDEDN SDEGVESGEE SAKAKKEKKD MRILNQKEAA QELALTRIFT DEDFKRINAA
610 620 630 640 650 660
NLKKTVTSAR KRPLEQDRAE FVKLNSIEMI YKKRKHDKES RLETVQAGRQ DRERFGWKDG
670 680 690 700 710
RVNEHCSKTN REKRKTKNFG MLRHKARSKV KKSFKDKQQA LRKHLLHQKK MK