Q9M1I1

PR
Gene name
At3g54460 (T14E10.30)
Protein name
F-box protein At3g54460
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT3G54460
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

44-144 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9M1I1

Entry ID Method Resolution Chain Position Source
AF-Q9M1I1-F1 Predicted AlphaFoldDB

103 variants for Q9M1I1

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH06314072 6 K>I No 1000Genomes
ENSVATH12757486 13 T>I No 1000Genomes
tmp_3_20167099_A_C 30 F>V No 1000Genomes
ENSVATH06314070 35 G>S No 1000Genomes
tmp_3_20167054_CATT_TATT,C 45 G>S No 1000Genomes
ENSVATH06314068 51 T>I No 1000Genomes
ENSVATH12757485 69 V>I No 1000Genomes
ENSVATH06314065 81 E>K No 1000Genomes
ENSVATH06314064 87 R>H No 1000Genomes
ENSVATH06314063 94 S>I No 1000Genomes
ENSVATH02503943 101 P>S No 1000Genomes
ENSVATH12757454 104 K>R No 1000Genomes
tmp_3_20166846_T_C 114 K>R No 1000Genomes
ENSVATH02503942 116 V>L No 1000Genomes
tmp_3_20166823_C_T 122 V>I No 1000Genomes
tmp_3_20166727_C_A 154 V>L No 1000Genomes
ENSVATH06314050 214 I>V No 1000Genomes
tmp_3_20166314_C_T 216 E>K No 1000Genomes
ENSVATH12757449 226 W>S No 1000Genomes
ENSVATH06314048 244 N>D No 1000Genomes
ENSVATH06314045 252 K>N No 1000Genomes
ENSVATH00419093 282 V>A No 1000Genomes
tmp_3_20166109_C_G 284 G>A No 1000Genomes
ENSVATH06314042 293 L>F No 1000Genomes
ENSVATH00419092 316 R>K No 1000Genomes
tmp_3_20166004_G_A 319 T>I No 1000Genomes
tmp_3_20165917_G_C 348 A>G No 1000Genomes
tmp_3_20165887_C_G 358 S>T No 1000Genomes
tmp_3_20165811_C_G 383 M>I No 1000Genomes
ENSVATH06314040 388 R>C No 1000Genomes
ENSVATH12757448 415 M>I No 1000Genomes
ENSVATH12757447 441 T>P No 1000Genomes
tmp_3_20165598_C_A 454 K>N No 1000Genomes
tmp_3_20165516_A_G 482 F>L No 1000Genomes
ENSVATH06314038 514 L>P No 1000Genomes
tmp_3_20165372_T_C 530 N>D No 1000Genomes
ENSVATH06314036 533 P>H No 1000Genomes
ENSVATH00419091 537 G>C No 1000Genomes
ENSVATH06314035 538 A>V No 1000Genomes
tmp_3_20165335_G_T 542 S>Y No 1000Genomes
ENSVATH12757427 546 E>K No 1000Genomes
tmp_3_20165270_T_C 564 R>G No 1000Genomes
tmp_3_20165257_G_A 568 T>I No 1000Genomes
ENSVATH14433329 569 D>G No 1000Genomes
ENSVATH00419090 575 D>N No 1000Genomes
ENSVATH00419089 581 D>E No 1000Genomes
ENSVATH06314033 616 D>N No 1000Genomes
tmp_3_20165050_C_G 637 G>A No 1000Genomes
ENSVATH06314032 638 A>S No 1000Genomes
ENSVATH14433327 651 S>N No 1000Genomes
ENSVATH12757394 696 L>I No 1000Genomes
tmp_3_20164868_C_A 698 A>S No 1000Genomes
ENSVATH14433325 701 F>I No 1000Genomes
tmp_3_20164843_C_T 706 R>Q No 1000Genomes
ENSVATH02503937 725 K>N No 1000Genomes
tmp_3_20164783_A_T 726 F>Y No 1000Genomes
ENSVATH06314030 759 V>I No 1000Genomes
ENSVATH06314029 762 T>S No 1000Genomes
ENSVATH06314028 778 S>F No 1000Genomes
tmp_3_20164580_G_T 794 P>T No 1000Genomes
ENSVATH14433293 831 V>I No 1000Genomes
ENSVATH00419088 840 G>D No 1000Genomes
tmp_3_20164430_T_A 844 S>C No 1000Genomes
ENSVATH06314025 846 T>A No 1000Genomes
tmp_3_20164409_T_C 851 M>V No 1000Genomes
tmp_3_20164376_G_T 862 L>I No 1000Genomes
tmp_3_20164343_T_A 873 N>Y No 1000Genomes
ENSVATH14433292 883 L>I No 1000Genomes
ENSVATH02503935 910 M>I No 1000Genomes
ENSVATH06314023 937 P>L No 1000Genomes
tmp_3_20164124_G_T 946 L>I No 1000Genomes
ENSVATH00419087 967 I>V No 1000Genomes
ENSVATH06314022 975 P>S No 1000Genomes
ENSVATH14433291 1012 A>G No 1000Genomes
tmp_3_20163914_T_C 1016 I>V No 1000Genomes
ENSVATH00419086 1031 W>S No 1000Genomes
ENSVATH06314020 1039 Q>H No 1000Genomes
ENSVATH00419084 1067 L>M No 1000Genomes
ENSVATH12757389 1069 L>I No 1000Genomes
tmp_3_20163633_T_C 1081 I>V No 1000Genomes
tmp_3_20163618_A_G 1086 Y>H No 1000Genomes
ENSVATH06314018 1095 T>A No 1000Genomes
tmp_3_20163537_T_C 1113 I>V No 1000Genomes
ENSVATH06314014 1150 N>Y No 1000Genomes
tmp_3_20163282_G_A 1170 P>L No 1000Genomes
ENSVATH02503931 1171 G>D No 1000Genomes
tmp_3_20163202_A_T 1197 L>M No 1000Genomes
ENSVATH06314012 1230 Y>C No 1000Genomes
tmp_3_20163012_T_C 1231 N>S No 1000Genomes
ENSVATH00419082 1238 M>K No 1000Genomes
ENSVATH14433287 1242 D>N No 1000Genomes
tmp_3_20162826_C_A 1266 V>F No 1000Genomes
ENSVATH06313999 1302 R>C No 1000Genomes
tmp_3_20162233_C_A 1318 K>N No 1000Genomes
ENSVATH02503925 1323 L>M No 1000Genomes
ENSVATH02503924 1325 G>A No 1000Genomes
ENSVATH12757372 1333 E>K No 1000Genomes
ENSVATH12757371 1338 R>L No 1000Genomes
tmp_3_20162109_C_A 1360 G>C No 1000Genomes
ENSVATH06313994 1362 M>I No 1000Genomes
tmp_3_20162090_G_C 1366 A>G No 1000Genomes
ENSVATH06313993 1368 Q>* No 1000Genomes
ENSVATH00419080 1373 K>Q No 1000Genomes

No associated diseases with Q9M1I1

6 regional properties for Q9M1I1

Type Name Position InterPro Accession
domain SNF2, N-terminal 333 - 983 IPR000330
domain Helicase, C-terminal 1185 - 1324 IPR001650
domain F-box domain 282 - 328 IPR001810
domain Zinc finger, CW-type 571 - 622 IPR011124
domain Helicase superfamily 1/2, ATP-binding domain 326 - 889 IPR014001
conserved_site Zinc finger, RING-type, conserved site 1063 - 1072 IPR017907

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
plasmodesma A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.

6 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP-dependent activity, acting on DNA Catalytic activity that acts to modify DNA, driven by ATP hydrolysis.
ATP-dependent chromatin remodeler activity An activity, driven by ATP hydrolysis, that modulates the contacts between histones and DNA, resulting in a change in chromosome architecture within the nucleosomal array, leading to chromatin remodeling.
helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q14527 HLTF Helicase-like transcription factor Homo sapiens (Human) PR
Q6PCN7 Hltf Helicase-like transcription factor Mus musculus (Mouse) PR
10 20 30 40 50 60
MADDHKLCGF LCTVLSVDSP DLLQSGSSCF IFNDGSVTGF KSENGLILSL TNPISNLQSL
70 80 90 100 110 120
ISSKGDHDVE NSGTIEDGRL ETPQKRRKCV EGESSGKRKT PKSKRRVLSG SKEKTVQGRK
130 140 150 160 170 180
RVKSIGMVNG SISVVQQLHA LVANKCLKII CRVVKVDKGE NGEERAVVLV DVYLPIELWS
190 200 210 220 230 240
GWQFPKSQAT AAALFKHLSC DWGLRVSILD GKSIWEEANG RIKAIWDLSD CHVFDCKLLC
250 260 270 280 290 300
NAPNSPKRRL FKLHEIFKSL PSPGNHDVSY SSRVLPSTDS CVSGVWDLSD DVLISILMKL
310 320 330 340 350 360
DTKDLFSIAA VCRLFRSLTS LIVPCMNLKL FPHQQAAVGW MLERERKAEV SSHPLYLSFD
370 380 390 400 410 420
TEDGFSFYVN AVTGDIITEA APMVKDFRGG MFCDEPGLGK TITALSLILK TQGTMADPPE
430 440 450 460 470 480
GLPIVWCTHK SDKKCAYYEY TSDQFTSNSM SAVKRFQSPS SCRNQVSFEA FRPLLESKSL
490 500 510 520 530 540
PFKQARLMDP DDQTLESKNS NFENEFETHI PASLDLKAQC RKSLGNVRKN LLPAYNGASE
550 560 570 580 590 600
LSEVMEAKRI SNWKKCGMIT GCKRKGLTDS DVESDIWMQC DSCSKWRRII DEGVSVTGSA
610 620 630 640 650 660
WFCSNNNDPA YQSCNDPEEL WDKSQPIKYL QGFYTKGASG EESDNISFFT SVLREHKSSV
670 680 690 700 710 720
SSTVKKALIW LAKLPLEKLS QMETVGLPGP VLGLKLDALG FQRIFRAFGL KSRVEKGVTK
730 740 750 760 770 780
WFYPKFLENL VFDVPALKVA LCQPLDTFRL YLSKATLIVV PTNLVNHWLT QIQKHVCSDQ
790 800 810 820 830 840
LRILVWADHI ELSPHSLAWD YDVVITTFSR LSAEWNPRKK SPLIQVHWLR VMLDEGHTLG
850 860 870 880 890 900
SSVSLTNKFQ MAVSLTACNR WLLTGTPTPN TPNSQLSHIQ PLLKFLHEEV YGENPKFWEA
910 920 930 940 950 960
GILRPFEAEM EEGRLRLLQL LQRCMISSRK KDLQMIPPCI KKVTYLNFLP GHARSYNELV
970 980 990 1000 1010 1020
ETVRRNILLA DWNDPSHVES LLNSKQWKFR SITISNVRLS CCVAGHIKMT DAGHDIKETM
1030 1040 1050 1060 1070 1080
DALLENDLDL WTEEYSFIQD SLIGGCNCKR CGEWCRLPVI TPCRHLLCLD CVALDSERCT
1090 1100 1110 1120 1130 1140
ISGCGYLYEM QTPETLARPE NPNPKWPVPK DLIELQPSYK QDDWNPDWQS TSSSKVSYLV
1150 1160 1170 1180 1190 1200
DRLRKLHEGN KKSILSFNKT DNDNLEDNPP GTSEAFLGKE LHGQDCGSQM VFVDKVLIFS
1210 1220 1230 1240 1250 1260
QFLEHIHVIE QQLTTAGIKF GKMYSPMQSY NKMKALAMFQ NDADCMALLM DGSGALGLDL
1270 1280 1290 1300 1310 1320
SFVTHVFLME PIWDKSLEEQ VISRAHRMGA KRPIFVETLT MRGTIEEQMM RFLEDAEKSD
1330 1340 1350 1360 1370
RLLSGDYIEA KQETTRSRRT LHDLVESNYL SHLSFVRSDG KMEFAASQLA GLKDHQLA