Q9M146
Gene name |
MGP4 |
Protein name |
UDP-D-xylose:L-fucose alpha-1,3-D-xylosyltransferase MGP4 |
Names |
Protein MALE GAMETOPHYTE DEFECTIVE 4, Rhamnogalacturonan xylosyltransferase MGP4 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT4G01220 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9M146
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9M146-F1 | Predicted | AlphaFoldDB |
22 variants for Q9M146
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH06411788 | 6 | F>L | No | 1000Genomes | |
| ENSVATH02608682 | 9 | Q>H | No | 1000Genomes | |
| tmp_4_515609_T_A | 14 | N>Y | No | 1000Genomes | |
| ENSVATH06411787 | 38 | L>I | No | 1000Genomes | |
| tmp_4_515524_C_A | 42 | G>V | No | 1000Genomes | |
| ENSVATH10488003 | 65 | F>L | No | 1000Genomes | |
| ENSVATH10488002 | 65 | F>S | No | 1000Genomes | |
| ENSVATH10488001 | 78 | W>L | No | 1000Genomes | |
| ENSVATH02608679 | 80 | D>G | No | 1000Genomes | |
| ENSVATH06411785 | 82 | S>A | No | 1000Genomes | |
| ENSVATH06411784 | 89 | F>L | No | 1000Genomes | |
| tmp_4_515381_C_T | 90 | V>I | No | 1000Genomes | |
| ENSVATH06411783 | 98 | V>I | No | 1000Genomes | |
| tmp_4_515213_C_A | 146 | A>S | No | 1000Genomes | |
| ENSVATH06411780 | 152 | A>S | No | 1000Genomes | |
| ENSVATH10488000 | 164 | Q>R | No | 1000Genomes | |
| tmp_4_514591_A_G | 180 | I>T | No | 1000Genomes | |
| tmp_4_514550_T_G | 194 | M>L | No | 1000Genomes | |
| ENSVATH02608645 | 226 | H>N | No | 1000Genomes | |
| tmp_4_514306_C_T | 247 | R>H | No | 1000Genomes | |
| ENSVATH02608643 | 250 | N>S | No | 1000Genomes | |
| ENSVATH00451397 | 288 | A>V | No | 1000Genomes |
No associated diseases with Q9M146
1 regional properties for Q9M146
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Nucleotide-diphospho-sugar transferase | 121 - 339 | IPR005069 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| Golgi trans cisterna | The Golgi cisterna farthest from the endoplasmic reticulum; the final processing compartment through which proteins pass before exiting the Golgi apparatus; the compartment in which N-linked protein glycosylation is completed. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| glycosyltransferase activity | Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor). |
| UDP-xylosyltransferase activity | Catalysis of the transfer of a xylosyl group from UDP-xylose to an acceptor molecule. |
| xylosyltransferase activity | Catalysis of the transfer of a xylosyl group to an acceptor molecule, typically another carbohydrate or a lipid. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| pollen tube development | The process whose specific outcome is the progression of a pollen tube over time, from its initial formation to a mature structure. |
| rhamnogalacturonan II biosynthetic process | The chemical reactions and pathways resulting in the formation of rhamnogalacturonan II, a low molecular mass (5 - 10KDa) pectic polysaccharide, conserved in the primary walls of dicotyledenous and monocotyledenous plants and gymnosperms. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9ZSJ2 | RGXT1 | UDP-D-xylose:L-fucose alpha-1,3-D-xylosyltransferase 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAQQKFLHQR | PIQNPFTNPF | SSSPLSTSSI | SNRPISLLSR | NGLLLLLALL | VILGVFLPWA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GSPLFPSPNK | LSPSQSKWRD | YSLPQAVKFV | AKNGTVIVCA | VSYPYLPFLN | NWLISVSRQK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| HQDQVLVIAE | DYATLYKVNE | KWPGHAVLIP | PALDSQTAHK | FGSQGFFNFT | ARRPQHLLEI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LELGYNVMYN | DVDMVWLQDP | FQYLEGKHDA | YFMDDMTAIK | PLDHSHDLPP | PGKKGRTYIC |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SCMIFLRPTN | GAKLLMKKWI | EELETQPWSR | AKKANDQPGF | NWALNKTANQ | VDMYLLSQAA |
| 310 | 320 | 330 | 340 | 350 | |
| FPTGGLYFKN | KTWVKETKGK | HAIIHNNYIV | GFEKKIKRFR | DFNLWLVDDH | ASESPLGKLE |