Q9LZW2

PR
Gene name
OFP1 (At5g01840, T20L15.110)
Protein name
Transcription repressor OFP1
Names
Ovate family protein 1, AtOFP1
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT5G01840
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

2-107 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9LZW2

Entry ID Method Resolution Chain Position Source
AF-Q9LZW2-F1 Predicted AlphaFoldDB

34 variants for Q9LZW2

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH10488690 4 N>K No 1000Genomes
ENSVATH13874046 23 D>N No 1000Genomes
tmp_5_324667_C_T 39 T>I No 1000Genomes
ENSVATH10488691 41 S>A No 1000Genomes
ENSVATH00600548 49 P>S No 1000Genomes
ENSVATH10488692 64 R>P No 1000Genomes
ENSVATH06905474 75 H>Y No 1000Genomes
tmp_5_324796_G_A 82 G>E No 1000Genomes
tmp_5_324820_C_T 90 T>I No 1000Genomes
ENSVATH00600549 98 T>I No 1000Genomes
ENSVATH00600549 98 T>N No 1000Genomes
ENSVATH06905476 110 F>L No 1000Genomes
tmp_5_324897_T_A 116 S>T No 1000Genomes
tmp_5_324942_C_A 131 H>N No 1000Genomes
tmp_5_324970_A_G 140 K>R No 1000Genomes
tmp_5_324983_T_G 144 F>L No 1000Genomes
tmp_5_324990_C_G 147 P>A No 1000Genomes
ENSVATH10488694 151 E>K No 1000Genomes
tmp_5_325039_C_T 163 A>V No 1000Genomes
tmp_5_325041_C_G 164 R>G No 1000Genomes
tmp_5_325042_G_C 164 R>P No 1000Genomes
tmp_5_325051_C_T 167 A>V No 1000Genomes
ENSVATH13874048 168 V>G No 1000Genomes
ENSVATH06905478 169 N>S No 1000Genomes
ENSVATH13874050 191 R>G No 1000Genomes
ENSVATH10488726 196 A>G No 1000Genomes
tmp_5_325144_G_T 198 R>L No 1000Genomes
tmp_5_325231_G_A 227 R>K No 1000Genomes
ENSVATH06905483 240 L>I No 1000Genomes
tmp_5_325278_A_G 243 N>D No 1000Genomes
tmp_5_325351_C_T 267 P>L No 1000Genomes
tmp_5_325350_C_A 267 P>T No 1000Genomes
tmp_5_325354_A_T 268 H>L No 1000Genomes
ENSVATH10488729 270 K>I No 1000Genomes

No associated diseases with Q9LZW2

2 regional properties for Q9LZW2

Type Name Position InterPro Accession
domain Ovate protein family, C-terminal 201 - 262 IPR006458
domain DNA-binding domain, ovate family-like 1 - 45 IPR025830

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoskeleton A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

4 GO annotations of biological process

Name Definition
cortical microtubule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cell cortex, i.e. just beneath the plasma membrane of a cell.
DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
negative regulation of DNA-templated transcription Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
regulation of unidimensional cell growth Any process that modulates the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8VZN1 OFP5 Transcription repressor OFP5 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MGNNYRFKLS ELIPNAWFYK LRDMSKSKKK NLQSQPNSTT SKKKHHAVPT PTSTTPLSPR
70 80 90 100 110 120
PPRRPSHSSK APPSHPPRKS SGNRLRHRAT VDSKSSTTSG DSTTTETGSF SPDFRSDQVL
130 140 150 160 170 180
LPDESLTGSW HSPCSSKLSK TATFTPPPEL ELRPIITKTA ATARKTAVNS PAGVRLRMRS
190 200 210 220 230 240
PRISVSSSAR RSGSSARRSR AVVKASVDPK RDFKESMEEM IAENKIRATK DLEELLACYL
250 260
CLNSDEYHAI IINVFKQIWL DLNLPPPHSK