AiPD: Autoinhibited Protein Database

Gene name	OFP5 (At4g18830, F13C5.5)
Protein name	Transcription repressor OFP5
Names	Ovate family protein 5, AtOFP5
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT4G18830
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

1-303 (Predicted disordered autoinhibitory region) PR

1-303 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q8VZN1-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
ENSVATH06719227	3	R>T	No	1000Genomes
ENSVATH06719228	9	P>H	No	1000Genomes
tmp_4_10337480_C_T	11	S>F	No	1000Genomes
ENSVATH11990053	21	A>T	No	1000Genomes
tmp_4_10337518_G_A	24	V>I	No	1000Genomes
tmp_4_10337548_T_C	34	S>P	No	1000Genomes
tmp_4_10337586_A_T	46	E>D	No	1000Genomes
ENSVATH00520908	51	N>K	No	1000Genomes
ENSVATH00520909	59	S>G	No	1000Genomes
ENSVATH06719229	64	R>Q	No	1000Genomes
tmp_4_10337660_G_A	71	S>N	No	1000Genomes
tmp_4_10337697_C_G	83	N>K	No	1000Genomes
tmp_4_10337809_G_A	121	V>M	No	1000Genomes
ENSVATH06719230	127	D>G	No	1000Genomes
tmp_4_10337863_G_A	139	V>M	No	1000Genomes
tmp_4_10337930_C_T	161	S>L	No	1000Genomes
ENSVATH00520910	167	V>F	No	1000Genomes
ENSVATH06719232	178	T>K	No	1000Genomes
ENSVATH06719232	178	T>R	No	1000Genomes
tmp_4_10337984_G_A	179	G>E	No	1000Genomes
tmp_4_10337994_T_A	182	S>R	No	1000Genomes
ENSVATH00520911	192	T>S	No	1000Genomes
ENSVATH06719234	194	T>A	No	1000Genomes
tmp_4_10338140_T_A	231	I>K	No	1000Genomes
ENSVATH02876895	235	E>G	No	1000Genomes
ENSVATH14249738	237	N>T	No	1000Genomes
tmp_4_10338160_A_C	238	K>Q	No	1000Genomes
ENSVATH06719235	249	K>N	No	1000Genomes
tmp_4_10338228_G_T	260	K>N	No	1000Genomes
tmp_4_10338251_A_C	268	H>P	No	1000Genomes
tmp_4_10338290_A_C	281	N>T	No	1000Genomes
tmp_4_10338412_T_C	322	C>R	No	1000Genomes
ENSVATH11990087	328	T>R	No	1000Genomes
ENSVATH02876896	344	N>D	No	1000Genomes
ENSVATH02876897	345	D>E	No	1000Genomes

Type	Name	Position	InterPro Accession
domain	Ovate protein family, C-terminal	284 - 345	IPR006458

		Description
EC Number
Subcellular Localization	Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
cortical cytoskeleton	The portion of the cytoskeleton that lies just beneath the plasma membrane.
nucleolus	A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

Name	Definition
No GO annotations for molecular function

Name	Definition
cortical microtubule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cell cortex, i.e. just beneath the plasma membrane of a cell.
embryo sac development	The process whose specific outcome is the progression of the embryo sac over time, from its formation to the mature structure. The process begins with the meiosis of the megasporocyte to form four haploid megaspores. Three of the megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. The two polar nuclei fuse resulting in a mononucleate diploid endosperm mother cell. The three antipodal cells degenerate.
negative regulation of DNA-templated transcription	Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q9LZW2	OFP1	Transcription repressor OFP1	Arabidopsis thaliana (Mouse-ear cress)	PR