Q9LZN0
Gene name |
ROPGEF7 (At5g02010, T7H20.60) |
Protein name |
Rop guanine nucleotide exchange factor 7 |
Names |
AtRopGEF7, Rho of plants guanine nucleotide exchange factor 7 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G02010 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9LZN0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9LZN0-F1 | Predicted | AlphaFoldDB |
33 variants for Q9LZN0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH03005642 | 2 | D>G | No | 1000Genomes | |
| tmp_5_383512_A_T | 7 | N>I | No | 1000Genomes | |
| ENSVATH06906394 | 11 | V>L | No | 1000Genomes | |
| ENSVATH10492610 | 35 | P>R | No | 1000Genomes | |
| ENSVATH10492609 | 35 | P>T | No | 1000Genomes | |
| ENSVATH10492611 | 36 | S>C | No | 1000Genomes | |
| tmp_5_383667_A_C | 59 | K>Q | No | 1000Genomes | |
| ENSVATH03005648 | 123 | T>A | No | 1000Genomes | |
| ENSVATH10492613 | 133 | M>I | No | 1000Genomes | |
| tmp_5_384148_A_T | 145 | E>V | No | 1000Genomes | |
| ENSVATH06906402 | 182 | N>K | No | 1000Genomes | |
| tmp_5_384463_G_A | 192 | E>K | No | 1000Genomes | |
| ENSVATH00600837 | 240 | Q>H | No | 1000Genomes | |
| tmp_5_384627_G_C | 246 | Q>H | No | 1000Genomes | |
| tmp_5_384637_A_G | 250 | K>E | No | 1000Genomes | |
| tmp_5_384658_A_T | 257 | I>L | No | 1000Genomes | |
| tmp_5_384698_C_A | 270 | A>D | No | 1000Genomes | |
| tmp_5_384707_A_C | 273 | E>A | No | 1000Genomes | |
| ENSVATH13876216 | 307 | C>F | No | 1000Genomes | |
| ENSVATH06906406 | 351 | E>D | No | 1000Genomes | |
| tmp_5_385065_G_C | 364 | E>Q | No | 1000Genomes | |
| ENSVATH06906408 | 365 | L>R | No | 1000Genomes | |
| ENSVATH06906411 | 453 | K>R | No | 1000Genomes | |
| ENSVATH10492650 | 456 | A>T | No | 1000Genomes | |
| tmp_5_385455_C_G | 466 | S>R | No | 1000Genomes | |
| tmp_5_385466_C_T | 470 | S>L | No | 1000Genomes | |
| tmp_5_385481_G_A | 475 | R>Q | No | 1000Genomes | |
| tmp_5_385507_C_T | 484 | P>S | No | 1000Genomes | |
| ENSVATH06906412 | 508 | P>S | No | 1000Genomes | |
| ENSVATH00600843 | 512 | N>D | No | 1000Genomes | |
| ENSVATH10492652 | 515 | L>F | No | 1000Genomes | |
| ENSVATH03005654 | 515 | L>S | No | 1000Genomes | |
| tmp_5_385613_G_C | 519 | S>T | No | 1000Genomes |
No associated diseases with Q9LZN0
1 regional properties for Q9LZN0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | PRONE domain | 61 - 440 | IPR005512 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| guanyl-nucleotide exchange factor activity | Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| plant-type cell wall organization | A process that results in the assembly and arrangement of constituent parts of the cellulose and pectin-containing cell wall, or in the disassembly of the cellulose and pectin-containing cell wall. This process is carried out at the cellular level. An example of this process is found in Arabidopsis thaliana. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| F4J1G1 | ROPGEF13 | Rop guanine nucleotide exchange factor 13 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDGSSENLPE | VEEKGRESSC | CSSETTRQEE | EEQSPSCTED | FTASPVSSRW | SVKNIDGEKK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KIRSDSRVSE | VEMMKERFSK | LLLGEDMSGS | GNGVCTALAI | SNAITNLCAT | LFGQLWRLEP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LPTEKKEMWR | REMEWLLCVS | DHIVEMTPTW | QTFPDGTKLE | IMTCRPRSDL | YVNLPALRKL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DNMLLEILDS | FEETEFWYVD | QGIMAHESAA | DGSSSFRKSF | QRQEDKWWLP | VPRVSPGGLQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ENSRKQLQHK | RDCTNQILKA | AMAINSITLA | DMEIPESYLE | SLPRKGRSCL | GDLIYRYISS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DQFSPECLLD | CLDLSSEHQA | IEIANRVESS | IYLWHKRTNS | KPATNTKTSW | EMVKELMVDA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DKLELMADRA | ESLLLSLKQR | FPGLPQTALD | MSKIQYNKDI | GKSILESYSR | VLESLAFNIV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ARIDDLLFVD | DLTRHSSDQI | PTTLGNNGND | APKSIAVPVS | NYTTPSYSPS | KQELRSSITV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| PPSPSRFKIP | HSSSVKRVLT | AYVTKNEPRL | KNLPLERSSR | SSSSERLSLE | KCMKESLNVS |
| NLDPGI |